Mutant p53 prolongs NF-κB activation and promotes chronic inflammation and inflammation-associated colorectal cancer T Cooks, IS Pateras, O Tarcic, H Solomon, AJ Schetter, S Wilder, ... Cancer cell 23 (5), 634-646, 2013 | 508 | 2013 |
Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 T Cooks, IS Pateras, LM Jenkins, KM Patel, AI Robles, J Morris, ... Nature communications 9 (1), 771, 2018 | 443 | 2018 |
p57KIP2: “Kip”ing the Cell under Control IS Pateras, K Apostolopoulou, K Niforou, A Kotsinas, VG Gorgoulis Molecular Cancer Research 7 (12), 1902-1919, 2009 | 199 | 2009 |
Dual function of p38α MAPK in colon cancer: suppression of colitis-associated tumor initiation but requirement for cancer cell survival J Gupta, I del Barco Barrantes, A Igea, S Sakellariou, IS Pateras, ... Cancer cell 25 (4), 484-500, 2014 | 190 | 2014 |
RNF20 links histone H2B ubiquitylation with inflammation and inflammation-associated cancer O Tarcic, IS Pateras, T Cooks, E Shema, J Kanterman, H Ashkenazi, ... Cell reports 14 (6), 1462-1476, 2016 | 150 | 2016 |
The DNA damage response and immune signaling alliance: Is it good or bad? Nature decides when and where IS Pateras, S Havaki, X Nikitopoulou, K Vougas, PA Townsend, ... Pharmacology & therapeutics 154, 36-56, 2015 | 144 | 2015 |
Validation and development of MTH1 inhibitors for treatment of cancer UW Berglund, K Sanjiv, H Gad, C Kalderen, T Koolmeister, T Pham, ... Annals of oncology 27 (12), 2275-2283, 2016 | 141 | 2016 |
Functional interplay between the DNA-damage-response kinase ATM and ARF tumour suppressor protein in human cancer G Velimezi, M Liontos, K Vougas, T Roumeliotis, J Bartkova, M Sideridou, ... Nature cell biology 15 (8), 967-977, 2013 | 130 | 2013 |
Downregulation of the KIP family members p27KIP1 and p57KIP2 by SKP2 and the role of methylation in p57KIP2 inactivation in nonsmall cell lung cancer IS Pateras, K Apostolopoulou, M Koutsami, K Evangelou, P Tsantoulis, ... International journal of cancer 119 (11), 2546-2556, 2006 | 99 | 2006 |
Mutant p53 gain of function underlies high expression levels of colorectal cancer stem cells markers H Solomon, N Dinowitz, IS Pateras, T Cooks, Y Shetzer, A Molchadsky, ... Oncogene 37 (12), 1669-1684, 2018 | 94 | 2018 |
Integrating the DNA damage and protein stress responses during cancer development and treatment VG Gorgoulis, DE Pefani, IS Pateras, IP Trougakos The Journal of pathology 246 (1), 12-40, 2018 | 93 | 2018 |
Inflammation, DNA Damage, Helicobacter pylori and Gastric Tumorigenesis P Kalisperati, E Spanou, IS Pateras, P Korkolopoulou, A Varvarigou, ... Frontiers in genetics 8, 20, 2017 | 89 | 2017 |
Gene amplification is a relatively frequent event leading to ZBTB7A (Pokemon) overexpression in non‐small cell lung cancer K Apostolopoulou, IS Pateras, K Evangelou, PK Tsantoulis, M Liontos, ... The Journal of Pathology: A Journal of the Pathological Society of Great …, 2007 | 83 | 2007 |
Centrosome abnormalities are frequently observed in non‐small‐cell lung cancer and are associated with aneuploidy and cyclin E overexpression MK Koutsami, PK Tsantoulis, M Kouloukoussa, K Apostolopoulou, ... The Journal of Pathology: A Journal of the Pathological Society of Great …, 2006 | 83 | 2006 |
The typhoid toxin promotes host survival and the establishment of a persistent asymptomatic infection L Del Bel Belluz, R Guidi, IS Pateras, L Levi, B Mihaljevic, SF Rouf, ... PLoS pathogens 12 (4), e1005528, 2016 | 79 | 2016 |
A single-nucleotide substitution mutator phenotype revealed by exome sequencing of human colon adenomas SI Nikolaev, SK Sotiriou, IS Pateras, F Santoni, S Sougioultzis, H Edgren, ... Cancer research 72 (23), 6279-6289, 2012 | 72 | 2012 |
The DNA damage checkpoint precedes activation of ARF in response to escalating oncogenic stress during tumorigenesis K Evangelou, J Bartkova, A Kotsinas, IS Pateras, M Liontos, G Velimezi, ... Cell Death & Differentiation 20 (11), 1485-1497, 2013 | 65 | 2013 |
Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability P Galanos, G Pappas, A Polyzos, A Kotsinas, I Svolaki, NN Giakoumakis, ... Genome biology 19, 1-18, 2018 | 63 | 2018 |
Age-associated inflammation connects RAS-induced senescence to stem cell dysfunction and epidermal malignancy L Golomb, A Sagiv, IS Pateras, A Maly, V Krizhanovsky, VG Gorgoulis, ... Cell Death & Differentiation 22 (11), 1764-1774, 2015 | 62 | 2015 |
How do cytokines trigger genomic instability? IL Aivaliotis, IS Pateras, M Papaioannou, C Glytsou, K Kontzoglou, ... BioMed Research International 2012 (1), 536761, 2012 | 61 | 2012 |