Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology R Channappanavar, S Perlman Seminars in immunopathology 39, 529-539, 2017 | 3053 | 2017 |
Dysregulated type I interferon and inflammatory monocyte-macrophage responses cause lethal pneumonia in SARS-CoV-infected mice R Channappanavar, AR Fehr, R Vijay, M Mack, J Zhao, DK Meyerholz, ... Cell host & microbe 19 (2), 181-193, 2016 | 1636 | 2016 |
Sex-based differences in susceptibility to severe acute respiratory syndrome coronavirus infection R Channappanavar, C Fett, M Mack, PP Ten Eyck, DK Meyerholz, ... The Journal of Immunology 198 (10), 4046-4053, 2017 | 1027 | 2017 |
IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes R Channappanavar, AR Fehr, J Zheng, C Wohlford-Lenane, ... The Journal of clinical investigation 129 (9), 3625-3639, 2019 | 637 | 2019 |
Airway memory CD4+ T cells mediate protective immunity against emerging respiratory coronaviruses J Zhao, J Zhao, AK Mangalam, R Channappanavar, C Fett, DK Meyerholz, ... Immunity 44 (6), 1379-1391, 2016 | 543 | 2016 |
T cell-mediated immune response to respiratory coronaviruses R Channappanavar, J Zhao, S Perlman Immunologic research 59, 118-128, 2014 | 518 | 2014 |
Virus-specific memory CD8 T cells provide substantial protection from lethal severe acute respiratory syndrome coronavirus infection R Channappanavar, C Fett, J Zhao, DK Meyerholz, S Perlman Journal of virology 88 (19), 11034-11044, 2014 | 491 | 2014 |
Middle East Respiratory Syndrome: Emergence of a Pathogenic Human Coronavirus PS Fehr AR, Channappanavar R Annual Reviews Medicine., 2016 | 362* | 2016 |
The conserved coronavirus macrodomain promotes virulence and suppresses the innate immune response during severe acute respiratory syndrome coronavirus infection AR Fehr, R Channappanavar, G Jankevicius, C Fett, J Zhao, J Athmer, ... MBio 7 (6), 10.1128/mbio. 01721-16, 2016 | 199 | 2016 |
MERS coronaviruses from camels in Africa exhibit region-dependent genetic diversity DKW Chu, KPY Hui, RAPM Perera, E Miguel, D Niemeyer, J Zhao, ... Proceedings of the National Academy of Sciences 115 (12), 3144-3149, 2018 | 192 | 2018 |
Coronaviruses: innate immunity, inflammasome activation, inflammatory cell death, and cytokines SJ Lee, R Channappanavar, TD Kanneganti Trends in immunology 41 (12), 1083-1099, 2020 | 187 | 2020 |
Mouse-adapted MERS coronavirus causes lethal lung disease in human DPP4 knockin mice K Li, CL Wohlford-Lenane, R Channappanavar, JE Park, JT Earnest, ... Proceedings of the National Academy of Sciences 114 (15), E3119-E3128, 2017 | 176 | 2017 |
Impaired NLRP3 inflammasome activation/pyroptosis leads to robust inflammatory cell death via caspase-8/RIPK3 during coronavirus infection M Zheng, EP Williams, RKS Malireddi, R Karki, B Banoth, A Burton, ... Journal of Biological Chemistry 295 (41), 14040-14052, 2020 | 175 | 2020 |
The nsp3 macrodomain promotes virulence in mice with coronavirus-induced encephalitis AR Fehr, J Athmer, R Channappanavar, JM Phillips, DK Meyerholz, ... Journal of virology 89 (3), 1523-1536, 2015 | 167 | 2015 |
Identification of an ideal adjuvant for receptor-binding domain-based subunit vaccines against Middle East respiratory syndrome coronavirus N Zhang, R Channappanavar, C Ma, L Wang, J Tang, T Garron, X Tao, ... Cellular & molecular immunology 13 (2), 180-190, 2016 | 146 | 2016 |
Human polyclonal immunoglobulin G from transchromosomic bovines inhibits MERS-CoV in vivo T Luke, H Wu, J Zhao, R Channappanavar, CM Coleman, JA Jiao, ... Science translational medicine 8 (326), 326ra21-326ra21, 2016 | 124 | 2016 |
Protective effect of intranasal regimens containing peptidic Middle East respiratory syndrome coronavirus fusion inhibitor against MERS-CoV infection R Channappanavar, L Lu, S Xia, L Du, DK Meyerholz, S Perlman, S Jiang The Journal of infectious diseases 212 (12), 1894-1903, 2015 | 106 | 2015 |
Age-related susceptibility to coronavirus infections: role of impaired and dysregulated host immunity R Channappanavar, S Perlman The Journal of clinical investigation 130 (12), 6204-6213, 2020 | 76 | 2020 |
Advancing age leads to predominance of inhibitory receptor expressing CD4 T cells R Channappanavar, BS Twardy, P Krishna, S Suvas Mechanisms of ageing and development 130 (10), 709-712, 2009 | 73 | 2009 |
The cellular redox environment alters antigen presentation JA Trujillo, NP Croft, NL Dudek, R Channappanavar, A Theodossis, ... Journal of Biological Chemistry 289 (40), 27979-27991, 2014 | 68 | 2014 |