Rupatadine, a new potent, orally active dual antagonist of histamine and platelet-activating factor (PAF) M Merlos, M Giral, D Balsa, R Ferrando, M Queralt, A Puigdemont, ... Journal of Pharmacology and Experimental Therapeutics 280 (1), 114-121, 1997 | 200 | 1997 |
A toxin–antitoxin module as a target for antimicrobial development VS Lioy, O Rey, D Balsa, T Pellicer, JC Alonso Plasmid 63 (1), 31-39, 2010 | 97 | 2010 |
One cannot rule them all: Are bacterial toxins-antitoxins druggable? WT Chan, D Balsa, M Espinosa FEMS microbiology reviews 39 (4), 522-540, 2015 | 90 | 2015 |
The chromosomal relBE2 toxin–antitoxin locus of Streptococcus pneumoniae: characterization and use of a bioluminescence resonance energy transfer assay to … C Nieto, T Pellicer, D Balsa, SK Christensen, K Gerdes, M Espinosa Molecular microbiology 59 (4), 1280-1296, 2006 | 69 | 2006 |
Variations in activity and inhibition with pH: the protonated amine is the substrate for monoamine oxidase, but uncharged inhibitors bind better TZE Jones, D Balsa, M Unzeta, RR Ramsay Journal of neural transmission 114, 707-712, 2007 | 44 | 2007 |
[(3-Pyridylalkyl) piperidylidene] benzocycloheptapyridine derivatives as dual antagonists of PAF and histamine E Carceller, M Merlos, M Giral, D Balsa, C Almansa, J Bartroli, ... Journal of medicinal chemistry 37 (17), 2697-2703, 1994 | 44 | 1994 |
The intestinal anti‐inflammatory effect of dersalazine sodium is related to a down‐regulation in IL‐17 production in experimental models of rodent colitis D Camuesco, ME Rodríguez‐Cabezas, N Garrido‐Mesa, M Cueto‐Sola, ... British journal of pharmacology 165 (3), 729-740, 2012 | 37 | 2012 |
Inhibition of Monoamine Oxidase from Bovine Retina by β‐Carbolines AF De Arribam, JM Lizcano, MD Balsa, M Unzeta Journal of pharmacy and pharmacology 46 (10), 809-813, 1994 | 37 | 1994 |
Characterization of monoamine oxidase activity present in human granulocytes and lymphocytes MD Balsa, N Gómez, M Unzeta Biochimica et Biophysica Acta (BBA)-General Subjects 992 (2), 140-144, 1989 | 35 | 1989 |
A comparative study of some kinetic and molecular properties of microsomal and mitochondrial monoamine oxidase N Gómez, D Balsa, M Unzeta Biochemical pharmacology 37 (18), 3407-3413, 1988 | 34 | 1988 |
The oxidation of dopamine by the semicarbazide-sensitive amine oxidase (SSAO) from rat vas deferens JM Lizcano, D Balsa, KF Tipton, M Unzeta Biochemical pharmacology 41 (8), 1107-1110, 1991 | 32 | 1991 |
Contribution of different amine oxidases to the metabolism of dopamine in bovine retina AF de Arriba, JM Lizcano, D Balsa, M Unzeta Biochemical pharmacology 42 (12), 2355-2361, 1991 | 29 | 1991 |
In vivo and in vitro pharmacological characterization of SVT‐40776, a novel M3 muscarinic receptor antagonist, for the treatment of overactive bladder C Salcedo, S Davalillo, J Cabellos, C Lagunas, D Balsa, ... British journal of pharmacology 156 (5), 807-817, 2009 | 27 | 2009 |
Bacterial toxin‐antitoxin systems as targets for the development of novel antibiotics JC Alonso, D Balsa, I Cherny, SK Christensen, M Espinosa, D Francuski, ... Enzyme‐Mediated Resistance to Antibiotics: Mechanisms, Dissemination, and …, 2007 | 27 | 2007 |
Effects of UR‐12633, a new antagonist of platelet‐activating factor, in rodent models of endotoxic shock M Giral, D Balsa, R Ferrando, M Merlos, J Garcia‐Rafanell, J Forn British journal of pharmacology 118 (5), 1223-1231, 1996 | 27 | 1996 |
Evaluation of responsive gene expression as a sensitive and specific biomarker in patients with ulcerative colitis J Román, N Planell, JJ Lozano, M Aceituno, M Esteller, C Pontes, D Balsa, ... Inflammatory bowel diseases 19 (2), 221-229, 2013 | 26 | 2013 |
The effect of side chain substitution at positions 2 and 3 of the heterocyclic ring of N-acetylenic analogues of tryptamine as monoamine oxidase inhibitors M Avila, MD Balsa, E Fernandez-Alvarez, KF Tipton, M Unzeta Biochemical pharmacology 45 (11), 2231-2237, 1993 | 26 | 1993 |
Design, Synthesis, and Structure−Activity Relationship Studies of Novel 1-[(1-Acyl-4-piperidyl)methyl]-1H-2-methylimidazo[4,5-c]pyridine Derivatives as Potent … E Carceller, M Merlos, M Giral, D Balsa, J García-Rafanell, J Forn Journal of medicinal chemistry 39 (2), 487-493, 1996 | 25 | 1996 |
Monoamine oxidase inhibitory potencies and selectivities of 2-[N-(2-propynyl)-aminomethyl]-1-methyl indole derivatives D Balsa, E Fernandez-Alverez, KF Tipton, M Unzeta Biochemical Society transactions 19 (1), 215-218, 1991 | 24 | 1991 |
1-alkyl-1-azoniabicyclo'2.2. 2 octane carbamate derivatives and their use as muscarinic receptor antagonists JLC Ruiz, CF Gallemi, AF Serrat, IJM Bono, DB Lopez, CL Arnal, CS Roca, ... US Patent 7,452,904, 2008 | 23 | 2008 |