Comparative mass spectrometry-based metabolomics strategies for the investigation of microbial secondary metabolites BC Covington, JA McLean, BO Bachmann Natural product reports 34 (1), 6-24, 2017 | 156 | 2017 |
Mapping microbial response metabolomes for induced natural product discovery DK Derewacz, BC Covington, JA McLean, BO Bachmann ACS chemical biology 10 (9), 1998-2006, 2015 | 100 | 2015 |
A natural product chemist's guide to unlocking silent biosynthetic gene clusters BC Covington, F Xu, MR Seyedsayamdost Annual review of biochemistry 90, 763-788, 2021 | 68 | 2021 |
Discovery and biosynthesis of streptosactin, a sactipeptide with an alternative topology encoded by commensal bacteria in the human microbiome LB Bushin, BC Covington, BE Rued, MJ Federle, MR Seyedsayamdost Journal of the American Chemical Society 142 (38), 16265-16275, 2020 | 53 | 2020 |
Total synthesis and stereochemical assignment of streptide NA Isley, Y Endo, ZC Wu, BC Covington, LB Bushin, MR Seyedsayamdost, ... Journal of the American Chemical Society 141 (43), 17361-17369, 2019 | 52 | 2019 |
Metabolic model for diversity-generating biosynthesis MD Tianero, E Pierce, S Raghuraman, D Sardar, JA McIntosh, ... Proceedings of the National Academy of Sciences 113 (7), 1772-1777, 2016 | 50 | 2016 |
Structuring microbial metabolic responses to multiplexed stimuli via self-organizing metabolomics maps CR Goodwin, BC Covington, DK Derewacz, CR McNees, JP Wikswo, ... Chemistry & biology 22 (5), 661-670, 2015 | 50 | 2015 |
Response of secondary metabolism of hypogean actinobacterial genera to chemical and biological stimuli BC Covington, JM Spraggins, AE Ynigez-Gutierrez, ZB Hylton, ... Applied and environmental microbiology 84 (19), e01125-18, 2018 | 38 | 2018 |
Quorum sensing in streptococcus mutans regulates production of tryglysin, a novel ras-ripp antimicrobial compound BE Rued, BC Covington, LB Bushin, G Szewczyk, I Laczkovich, ... MBio 12 (2), 10.1128/mbio. 02688-20, 2021 | 34 | 2021 |
Unlocking cryptic metabolites with mass spectrometry-guided transposon mutant selection A Yoshimura, BC Covington, É Gallant, C Zhang, A Li, ... ACS chemical biology 15 (10), 2766-2774, 2020 | 19 | 2020 |
Bicyclostreptins are radical SAM enzyme-modified peptides with unique cyclization motifs LB Bushin, BC Covington, KA Clark, A Caruso, MR Seyedsayamdost Nature Chemical Biology 18 (10), 1135-1143, 2022 | 18 | 2022 |
MetEx, a metabolomics explorer application for natural product discovery BC Covington, MR Seyedsayamdost ACS chemical biology 16 (12), 2825-2833, 2021 | 17 | 2021 |
Biosynthesis-guided discovery reveals enteropeptins as alternative sactipeptides containing N-methylornithine KA Clark, BC Covington, MR Seyedsayamdost Nature chemistry 14 (12), 1390-1398, 2022 | 9 | 2022 |
Vitamin B3 Triggers Biosynthesis of Secondary Metabolite Dormancy Signals in Streptococcus suis BC Covington, MR Seyedsayamdost Journal of the American Chemical Society 144 (33), 14997-15001, 2022 | 5 | 2022 |
Biosynthesis-Guided Discovery of Enteropeptins, Unusual Sactipeptides Containing an N-Methylornithine KA Clark, BC Covington, MR Seyedsayamdost | 4 | 2021 |
Guidelines for metabolomics-guided transposon mutagenesis for microbial natural product discovery BC Covington, MR Seyedsayamdost Methods in enzymology 665, 305-323, 2022 | 2 | 2022 |
Antibacterial agents MR Seyedsayamdost, MJ Federle, BC Covington, LB Bushin, J Ambrose US Patent App. 18/266,325, 2024 | | 2024 |
Metabolomics Explorer (MetEx) for Cryptic Natural Products or Antibiotic Drug Discovery M Seyedsayamdost, B Covington | | 2021 |
Tryglysin A and B Novel, Selective, and Potent Antibacterial Agents Against Streptococcus Bacteria M Seyedsayamdost, M Federle, B Covington, L Bushin, B Rued, ... | | 2021 |
Total Synthesis of (–)-Streptide EM Carreira, N Sievertsen Synfacts 16 (02), 0133, 2020 | | 2020 |