| Mechanism of isoniazid‐induced hepatotoxicity: then and now I Metushi, J Uetrecht, E Phillips British journal of clinical pharmacology 81 (6), 1030-1036, 2016 | 238 | 2016 |
| A fresh look at the mechanism of isoniazid‐induced hepatotoxicity IG Metushi, P Cai, X Zhu, T Nakagawa, JP Uetrecht Clinical Pharmacology & Therapeutics 89 (6), 911-914, 2011 | 222 | 2011 |
| Treatment of PD‐1−/− mice with amodiaquine and anti‐CTLA4 leads to liver injury similar to idiosyncratic liver injury in patients IG Metushi, MA Hayes, J Uetrecht Hepatology 61 (4), 1332-1342, 2015 | 153 | 2015 |
| T cell–mediated hypersensitivity reactions to drugs R Pavlos, S Mallal, D Ostrov, S Buus, I Metushi, B Peters, E Phillips Annual review of medicine 66 (1), 439-454, 2015 | 153 | 2015 |
| Automated benchmarking of peptide-MHC class I binding predictions T Trolle, IG Metushi, JA Greenbaum, Y Kim, J Sidney, O Lund, A Sette, ... Bioinformatics 31 (13), 2174-2181, 2015 | 144 | 2015 |
| Detection of anti‐isoniazid and anti‐cytochrome P450 antibodies in patients with isoniazid‐induced liver failure IG Metushi, C Sanders, TALFS Group, WM Lee, J Uetrecht Hepatology, 2014 | 143 | 2014 |
| Direct oxidation and covalent binding of isoniazid to rodent liver and human hepatic microsomes: humans are more like mice than rats IG Metushi, T Nakagawa, J Uetrecht Chemical research in toxicology 25 (11), 2567-2576, 2012 | 112 | 2012 |
| Near death from a novel synthetic opioid labeled U-47700: emergence of a new opioid class A Schneir, IG Metushi, C Sloane, DJ Benaron, RL Fitzgerald Clinical Toxicology 55 (1), 51-54, 2017 | 71 | 2017 |
| Animal models of idiosyncratic drug reactions W Ng, ARM Lobach, X Zhu, X Chen, F Liu, IG Metushi, A Sharma, J Li, ... Advances in pharmacology 63, 81-135, 2012 | 69 | 2012 |
| Development of a novel mouse model of amodiaquine-induced liver injury with a delayed onset IG Metushi, P Cai, D Dervovic, F Liu, A Lobach, T Nakagawa, J Uetrecht Journal of immunotoxicology 12 (3), 247-260, 2015 | 43 | 2015 |
| Assessment and comparison of vitreous humor as an alternative matrix for forensic toxicology screening by GC–MS IG Metushi, RL Fitzgerald, IM McIntyre Journal of Analytical Toxicology 40 (4), 243-247, 2016 | 42 | 2016 |
| Mild isoniazid-induced liver injury in humans is associated with an increase in Th17 cells and T cells producing IL-10 IG Metushi, X Zhu, X Chen, MA Gardam, J Uetrecht Chemical research in toxicology 27 (4), 683-689, 2014 | 41 | 2014 |
| Isoniazid-induced liver injury and immune response in mice IG Metushi, J Uetrecht Journal of immunotoxicology 11 (4), 383-392, 2014 | 34 | 2014 |
| High-dose loperamide abuse–associated ventricular arrhythmias CW O’Connell, AA Schricker, AB Schneir, IG Metushi, ... HeartRhythm case reports 2 (3), 232-236, 2016 | 23 | 2016 |
| Lack of liver injury in Wistar rats treated with the combination of isoniazid and rifampicin IG Metushi, J Uetrecht Molecular and cellular biochemistry 387, 9-17, 2014 | 22 | 2014 |
| Evaluation of the Waters MassTrak LC–MS/MS assay for tacrolimus and a comparison to the Abbott architect immunoassay A Saitman, IG Metushi, DS Mason, RL Fitzgerald Therapeutic Drug Monitoring 38 (3), 300-304, 2016 | 21 | 2016 |
| Acyclovir has low but detectable influence on HLA-B* 57: 01 specificity without inducing hypersensitivity IG Metushi, A Wriston, P Banerjee, BO Gohlke, AM English, A Lucas, ... PLoS One 10 (5), e0124878, 2015 | 18 | 2015 |
| Titanium (IV) complexes of disulfide-linked schiff bases A Donzelli, I Metushi, PG Potvin Inorganic Chemistry 51 (9), 5138-5145, 2012 | 16 | 2012 |
| Protein Targets of Isoniazid-Reactive Metabolites in Mouse Liver in Vivo YM Koen, NA Galeva, IG Metushi, J Uetrecht, RP Hanzlik Chemical Research in Toxicology 29 (6), 1064-1072, 2016 | 15 | 2016 |
| IgG3 Is the Dominant Subtype of Anti-isoniazid Antibodies in Patients with Isoniazid-Induced Liver Failure IG Metushi, WM Lee, J Uetrecht Chemical Research in Toxicology 27 (5), 738-740, 2014 | 15 | 2014 |
