Identification of potent COVID-19 main protease (Mpro) inhibitors from natural polyphenols: an in silico strategy unveils a hope against CORONA S Adem, V Eyupoglu, I Sarfraz, A Rasul, M Ali Preprints 2020, 2020030333, 2020 | 259 | 2020 |
Caffeic acid derivatives (CAFDs) as inhibitors of SARS-CoV-2: CAFDs-based functional foods as a potential alternative approach to combat COVID-19 Ş Adem, V Eyupoglu, I Sarfraz, A Rasul, AF Zahoor, M Ali, M Abdalla, ... Phytomedicine 85, 153310, 2021 | 122 | 2021 |
Synthesis, spectroscopic characterizations, enzyme inhibition, molecular docking study and DFT calculations of new Schiff bases of sulfa drugs S Alyar, T Şen, ÜÖ Özmen, H Alyar, Ş Adem, C Şen Journal of Molecular Structure 1185, 416-424, 2019 | 67 | 2019 |
Ginkgetin: A natural biflavone with versatile pharmacological activities M Adnan, A Rasul, G Hussain, MA Shah, MK Zahoor, H Anwar, I Sarfraz, ... Food and Chemical Toxicology 145, 111642, 2020 | 66 | 2020 |
Synthesis, spectroscopic characterizations, carbonic anhydrase II inhibitory activity, anticancer activity and docking studies of new Schiff bases of sulfa drugs S Alyar, ÜÖ Özmen, Ş Adem, H Alyar, E Bilen, K Kaya Journal of Molecular Structure 1223, 128911, 2021 | 53 | 2021 |
Purification of rat kidney glucose 6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase, and glutathione reductase enzymes using 2′, 5′-ADP Sepharose 4B affinity in a … S Adem, M Ciftci Protein Expression and Purification 81 (1), 1-4, 2012 | 52 | 2012 |
Hispolon: A natural polyphenol and emerging cancer killer by multiple cellular signaling pathways A Sarfraz, A Rasul, I Sarfraz, MA Shah, G Hussain, N Shafiq, M Masood, ... Environmental Research 190, 110017, 2020 | 48 | 2020 |
Synthesis, characterization, antimicrobial activity, carbonic anhydrase enzyme inhibitor effects, and computational studies on new Schiff bases of Sulfa drugs and their Pd (II … S Alyar, C Şen, H Alyar, Ş Adem, A Kalkanci, UO Ozdemir Journal of Molecular Structure 1171, 214-222, 2018 | 48 | 2018 |
6-Phosphogluconate dehydrogenase fuels multiple aspects of cancer cells: from cancer initiation to metastasis and chemoresistance I Sarfraz, A Rasul, G Hussain, MA Shah, FA Zahoor, M Asrar, Z Selamoglu, ... BioFactors, 2020 | 45 | 2020 |
The isolation of secondary metabolites from Rheum ribes L. and the synthesis of new semi-synthetic anthraquinones: Isolation, synthesis and biological activity IH Gecibesler, F Disli, S Bayindir, M Toprak, AR Tufekci, AS Yaglıoglu, ... Food Chemistry 342, 128378, 2021 | 40 | 2021 |
In vitro effects of some flavonoids and phenolic acids on human pyruvate kinase isoenzyme M2 E Aslan, C Guler, S Adem Journal of enzyme inhibition and medicinal chemistry 31 (2), 314-317, 2016 | 39 | 2016 |
Investigation of the effects of some phenolic compounds on the Activities of glucose‐6‐phosphate dehydrogenase and 6‐Phosphogluconate dehydrogenase from human erythrocytes S Adem, V Comakli, M Kuzu, R Demirdag Journal of biochemical and molecular toxicology 28 (11), 510-514, 2014 | 37 | 2014 |
Physcion and physcion 8-O-β-D-glucopyranoside: natural anthraquinones with potential anticancer activities M Adnan, A Rasul, G Hussain, MA Shah, I Sarfraz, B Nageen, A Riaz, ... Current Drug Targets 22 (5), 488-504, 2021 | 32 | 2021 |
Purification and biochemical characterization of glucose 6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase and glutathione reductase from rat lung and inhibition … S Adem, M Ciftci Journal of enzyme inhibition and medicinal chemistry 31 (6), 1342-1348, 2016 | 32 | 2016 |
Synthesis, characterization, antimicrobial activity and carbonic anhydrase enzyme inhibitor effects of salicilaldehyde-N-methyl p-toluenesulfonylhydrazone and its Palladium (II … S Alyar, Ş Adem Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 131, 294-302, 2014 | 28 | 2014 |
Multidimensional in silico strategy for identification of natural polyphenols-based SARS-CoV-2 main protease (Mpro) inhibitors to unveil a hope against COVID-19 Ş Adem, V Eyupoglu, IM Ibrahim, I Sarfraz, A Rasul, M Ali, AA Elfiky Computers in biology and medicine 145, 105452, 2022 | 25 | 2022 |
Germacrone: A potent secondary metabolite with therapeutic potential in metabolic diseases, cancer and viral infections A Riaz, A Rasul, N Kanwal, G Hussain, MA Shah, I Sarfraz, R Ishfaq, ... Current Drug Metabolism 21 (14), 1079-1090, 2020 | 25 | 2020 |
Synthesis, characterization, molecular docking and in vitro screening of new metal complexes with coumarin Schiff base as anticholine esterase and antipancreatic cholesterol … Ö Şahin, Ü Özmen Özdemir, N Seferoğlu, Ş Adem, Z Seferoğlu Journal of Biomolecular Structure and Dynamics 40 (10), 4460-4474, 2022 | 24 | 2022 |
In vitro effects of some flavones on human pyruvate kinase isoenzyme M2 E Aslan, S Adem Journal of Biochemical and Molecular Toxicology 29 (3), 109-113, 2015 | 24 | 2015 |
Phytochemical composition, antioxidant, enzyme inhibition, antimicrobial effects, and molecular docking studies of Centaurea sivasica Ü Yırtıcı, A Ergene, MN Atalar, Ş Adem South African Journal of Botany 144, 58-71, 2022 | 23 | 2022 |