Localization of a novel v-erbB-related gene, c-erbB-2, on human chromosome 17 and its amplification in a gastric cancer cell line SI Fukushige, KI Matsubara, M Yoshida, M Sasaki, T Suzuki, K Semba, ... Molecular and cellular biology, 1986 | 528 | 1986 |
Two erbA homologs encoding proteins with different T3 binding capacities are transcribed from opposite DNA strands of the same genetic locus N Miyajima, R Horiuchi, Y Shibuya, S Fukushige, K Matsubara, ... Cell 57 (1), 31-39, 1989 | 308 | 1989 |
Genomic targeting with a positive-selection lox integration vector allows highly reproducible gene expression in mammalian cells. S Fukushige, B Sauer Proceedings of the National Academy of Sciences 89 (17), 7905-7909, 1992 | 306 | 1992 |
The yes-related cellular gene lyn encodes a possible tyrosine kinase similar to p56lck Y Yamanashi, SI Fukushige, K Semba, J Sukegawa, N Miyajima, ... Molecular and cellular biology, 1987 | 288 | 1987 |
Isolation and characterization of the active cDNA of the human cell cycle gene (RCC1) involved in the regulation of onset of chromosome condensation. M Ohtsubo, R Kai, N Furuno, T Sekiguchi, M Sekiguchi, H Hayashida, ... Genes & development 1 (6), 585-593, 1987 | 268 | 1987 |
Identification of two novel members of erbA superfamily by molecular cloning: the gene products of the two are highly related to each other N Miyajtma, Y Kandowaki, S Fukushige, S Shimizu, K Semba, ... Nucleic acids research 16 (23), 11057-11074, 1988 | 240 | 1988 |
Product modularity for life cycle design Y Umeda, S Fukushige, K Tonoike, S Kondoh CIRP annals 57 (1), 13-16, 2008 | 187 | 2008 |
The interacting domains of three MutL heterodimers in man: hMLH1 interacts with 36 homologous amino acid residues within hMLH3, hPMS1 and hPMS2 E Kondo, A Horii, S Fukushige Nucleic acids research 29 (8), 1695-1702, 2001 | 162 | 2001 |
The Thymine DNA Glycosylase MBD4 Represses Transcription and Is Associated with Methylated p16INK4a and hMLH1 Genes E Kondo, Z Gu, A Horii, S Fukushige Molecular and cellular biology 25 (11), 4388-4396, 2005 | 159 | 2005 |
Chromosomal translocation and inverted duplication associated with integrated hepatitis B virus in hepatocellular carcinomas T Tokino, S Fukushige, T Nakamura, T Nagaya, T Murotsu, K Shiga, ... Journal of virology 61 (12), 3848-3854, 1987 | 148 | 1987 |
Frequent gain of copy number on the long arm of chromosome 20 in human pancreatic adenocarcinoma S Fukushige, FM Waldman, M Kimura, T Abe, T Furukawa, M Sunamura, ... Genes, Chromosomes and Cancer 19 (3), 161-169, 1997 | 145 | 1997 |
Primary structure of human pancreatic secretory trypsin inhibitor (PSTI) gene A Horii, T Kobayashi, N Tomita, T Yamamoto, S Fukushige, T Murotsu, ... Biochemical and biophysical research communications 149 (2), 635-641, 1987 | 132 | 1987 |
DCK is frequently inactivated in acquired gemcitabine-resistant human cancer cells Y Saiki, Y Yoshino, H Fujimura, T Manabe, Y Kudo, M Shimada, N Mano, ... Biochemical and biophysical research communications 421 (1), 98-104, 2012 | 126 | 2012 |
Infrequent somatic mutations of thep73genein various human cancers S Han, S Semba, T Abe, N Makino, T Furukawa, S Fukushige, ... European Journal of Surgical Oncology (EJSO) 25 (2), 194-198, 1999 | 122 | 1999 |
DNA methylation in cancer: a gene silencing mechanism and the clinical potential of its biomarkers S Fukushige, A Horii The Tohoku journal of experimental medicine 229 (3), 173-185, 2013 | 113 | 2013 |
Genomic analysis of DUSP6, a dual specificity MAP kinase phosphatase, in pancreatic cancer T Furukawa, T Yatsuoka, EM Youssef, T Abe, T Yokoyama, S Fukushige, ... Cytogenetics and cell genetics 82 (3-4), 156-159, 1998 | 97 | 1998 |
A yeast two-hybrid assay provides a simple way to evaluate the vast majority of hMLH1 germ-line mutations E Kondo, H Suzuki, A Horii, S Fukushige Cancer research 63 (12), 3302-3308, 2003 | 92 | 2003 |
Molecular cloning of an oncogene from a human hepatocellular carcinoma. T Ochiya, A Fujiyama, S Fukushige, I Hatada, K Matsubara Proceedings of the National Academy of Sciences 83 (14), 4993-4997, 1986 | 91 | 1986 |
Structure of human cholecystokinin gene and its chromosomal location T Yoosuke, F Shinichi, M Tomoaki, M Kenichi Gene 50 (1-3), 353-360, 1986 | 90 | 1986 |
Adenovirus-mediated delivery of the PTEN gene inhibits cell growth by induction of apoptosis in endometrial cancer. A Sakurada, H Hamada, S Fukushige, T Yokoyama, K Yoshinaga, ... International journal of oncology 15 (6), 1069-1143, 1999 | 82 | 1999 |