Molecular mimicry of host sialylated glycans allows a bacterial pathogen to engage neutrophil Siglec-9 and dampen the innate immune response AF Carlin, S Uchiyama, YC Chang, AL Lewis, V Nizet, A Varki Blood, The Journal of the American Society of Hematology 113 (14), 3333-3336, 2009 | 461 | 2009 |
The Ashwell receptor mitigates the lethal coagulopathy of sepsis PK Grewal, S Uchiyama, D Ditto, N Varki, DT Le, V Nizet, JD Marth Nature medicine 14 (6), 648-655, 2008 | 428 | 2008 |
Invariant natural killer T cells recognize glycolipids from pathogenic Gram-positive bacteria Y Kinjo, P Illarionov, JL Vela, B Pei, E Girardi, X Li, Y Li, M Imamura, ... Nature immunology 12 (10), 966-974, 2011 | 405 | 2011 |
The surface-anchored NanA protein promotes pneumococcal brain endothelial cell invasion S Uchiyama, AF Carlin, A Khosravi, S Weiman, A Banerjee, D Quach, ... The Journal of experimental medicine 206 (9), 1845, 2009 | 203 | 2009 |
Streptolysin O Rapidly Impairs Neutrophil Oxidative Burst and Antibacterial Responses to Group A Streptococcus S Uchiyama, S Döhrmann, AM Timmer, N Dixit, M Ghochani, T Bhandari, ... Frontiers in immunology 6, 581, 2015 | 105 | 2015 |
Activation of brain endothelium by pneumococcal neuraminidase NanA promotes bacterial internalization A Banerjee, NM Van Sorge, TR Sheen, S Uchiyama, TJ Mitchell, ... Cellular microbiology 12 (11), 1576-1588, 2010 | 99 | 2010 |
DNase Sda1 Allows Invasive M1T1 Group A Streptococcus to Prevent TLR9-Dependent Recognition S Uchiyama, F Andreoni, RA Schuepbach, V Nizet, AS Zinkernagel PLoS pathogens 8 (6), e1002736, 2012 | 97 | 2012 |
Inducing host protection in pneumococcal sepsis by preactivation of the Ashwell-Morell receptor PK Grewal, PV Aziz, S Uchiyama, GR Rubio, RD Lardone, D Le, NM Varki, ... Proceedings of the National Academy of Sciences 110 (50), 20218-20223, 2013 | 88 | 2013 |
Leukocyte inflammatory responses provoked by pneumococcal sialidase YC Chang, S Uchiyama, A Varki, V Nizet MBio 3 (1), 10.1128/mbio. 00220-11, 2012 | 72 | 2012 |
Increased Neutrophil Extracellular Trap–Mediated Staphylococcus aureus Clearance Through Inhibition of Nuclease Activity by Clindamycin and Immunoglobulin K Schilcher, F Andreoni, S Uchiyama, T Ogawa, RA Schuepbach, ... The Journal of infectious diseases 210 (3), 473-482, 2014 | 65 | 2014 |
O-Acetylation of sialic acid on Group B Streptococcus inhibits neutrophil suppression and virulence S Weiman, S Uchiyama, FYC Lin, D Chaffin, A Varki, V Nizet, AL Lewis The Biochemical journal 428 (2), 163, 2010 | 48 | 2010 |
Importance of Toll-Like Receptor 9 in Host Defense against M1T1 Group A Streptococcus Infections AS Zinkernagel, P Hruz, S Uchiyama, M von Köckritz-Blickwede, ... Journal of innate immunity 4 (2), 213-218, 2012 | 39 | 2012 |
Oropharyngeal group A streptococcal colonization disrupts latent Epstein-Barr virus infection S Ueda, S Uchiyama, T Azzi, C Gysin, C Berger, M Bernasconi, ... The Journal of infectious diseases 209 (2), 255-264, 2014 | 34 | 2014 |
Evolutionary inactivation of a sialidase in group B Streptococcus M Yamaguchi, Y Hirose, M Nakata, S Uchiyama, Y Yamaguchi, K Goto, ... Scientific reports 6 (1), 28852, 2016 | 27 | 2016 |
Brain Abscess Caused by Streptococcus pyogenes in a Previously Healthy Child W Dehority, S Uchiyama, A Khosravi, V Nizet Journal of clinical microbiology 44 (12), 4613-4615, 2006 | 20 | 2006 |
The IL-8 protease SpyCEP is detrimental for Group A Streptococcus host-cells interaction and biofilm formation F Andreoni, T Ogawa, M Ogawa, J Madon, S Uchiyama, RA Schuepbach, ... Frontiers in microbiology 5, 339, 2014 | 19 | 2014 |
Coiled-coil irregularities of the M1 protein structure promote M1–fibrinogen interaction and influence group A Streptococcus host cell interactions and virulence S Uchiyama, F Andreoni, C Zürcher, K Schilcher, M Ender, J Madon, ... Journal of Molecular Medicine 91, 861-869, 2013 | 17 | 2013 |
The Ashwell-Morell receptor mitigates the lethal coagulopathy of sepsis PK Grewal, S Uchiyama, D Ditto, N Varki, DT Le, V Nizet, JD Marth EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 39, 31-31, 2009 | 2 | 2009 |