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Slava Epelman
Slava Epelman
University Health Network
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Origin and functions of tissue macrophages
S Epelman, KJ Lavine, GJ Randolph
Immunity 41 (1), 21-35, 2014
17582014
Embryonic and adult-derived resident cardiac macrophages are maintained through distinct mechanisms at steady state and during inflammation
S Epelman, KJ Lavine, AE Beaudin, DK Sojka, JA Carrero, B Calderon, ...
Immunity 40 (1), 91-104, 2014
14852014
Origin, fate and dynamics of macrophages at central nervous system interfaces
T Goldmann, P Wieghofer, MJC Jordão, F Prutek, N Hagemeyer, ...
Nature immunology 17 (7), 797-805, 2016
10782016
Distinct macrophage lineages contribute to disparate patterns of cardiac recovery and remodeling in the neonatal and adult heart
KJ Lavine, S Epelman, K Uchida, KJ Weber, CG Nichols, JD Schilling, ...
Proceedings of the National Academy of Sciences 111 (45), 16029-16034, 2014
7482014
Self-renewing resident cardiac macrophages limit adverse remodeling following myocardial infarction
SA Dick, JA Macklin, S Nejat, A Momen, X Clemente-Casares, ...
Nature immunology 20 (1), 29-39, 2019
6752019
Chronic heart failure and inflammation: what do we really know?
SA Dick, S Epelman
Circulation research 119 (1), 159-176, 2016
6662016
Role of innate and adaptive immune mechanisms in cardiac injury and repair
S Epelman, PP Liu, DL Mann
Nature Reviews Immunology 15 (2), 117-129, 2015
6432015
The human heart contains distinct macrophage subsets with divergent origins and functions
G Bajpai, C Schneider, N Wong, A Bredemeyer, M Hulsmans, ...
Nature medicine 24 (8), 1234-1245, 2018
5602018
Tissue resident CCR2− and CCR2+ cardiac macrophages differentially orchestrate monocyte recruitment and fate specification following myocardial injury
G Bajpai, A Bredemeyer, W Li, K Zaitsev, AL Koenig, I Lokshina, J Mohan, ...
Circulation research 124 (2), 263-278, 2019
5392019
Self-renewing resident arterial macrophages arise from embryonic CX3CR1+ precursors and circulating monocytes immediately after birth
S Ensan, A Li, R Besla, N Degousee, J Cosme, M Roufaiel, EA Shikatani, ...
Nature immunology 17 (2), 159-168, 2016
3752016
The pancreas anatomy conditions the origin and properties of resident macrophages
B Calderon, JA Carrero, ST Ferris, DK Sojka, L Moore, S Epelman, ...
The Journal of experimental medicine 212 (10), 1497, 2015
3222015
Detection of soluble angiotensin-converting enzyme 2 in heart failure: insights into the endogenous counter-regulatory pathway of the renin-angiotensin-aldosterone system
S Epelman, WHW Tang, SY Chen, F Van Lente, GS Francis, S Sen
Journal of the American College of Cardiology 52 (9), 750-754, 2008
3112008
Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis
I Sergin, TD Evans, X Zhang, S Bhattacharya, CJ Stokes, E Song, S Ali, ...
Nature communications 8 (1), 15750, 2017
2942017
Primitive embryonic macrophages are required for coronary development and maturation
J Leid, J Carrelha, H Boukarabila, S Epelman, SEW Jacobsen, KJ Lavine
Circulation research 118 (10), 1498-1511, 2016
2772016
Three tissue resident macrophage subsets coexist across organs with conserved origins and life cycles
SA Dick, A Wong, H Hamidzada, S Nejat, R Nechanitzky, S Vohra, ...
Science immunology 7 (67), eabf7777, 2022
2592022
Induction of lysosomal biogenesis in atherosclerotic macrophages can rescue lipid-induced lysosomal dysfunction and downstream sequelae
R Emanuel, I Sergin, S Bhattacharya, JN Turner, S Epelman, C Settembre, ...
Arteriosclerosis, thrombosis, and vascular biology 34 (9), 1942-1952, 2014
2302014
Soluble angiotensin-converting enzyme 2 in human heart failure: relation with myocardial function and clinical outcomes
S Epelman, K Shrestha, RW Troughton, GS Francis, S Sen, AL Klein, ...
Journal of cardiac failure 15 (7), 565-571, 2009
2222009
Effect of convalescent plasma on organ support–free days in critically ill patients with COVID-19: a randomized clinical trial
H Abdelhady, M Abdelrazik, Z Abdi, D Abdo, A Abdulle, L Abel, ...
Jama 326 (17), 1690-1702, 2021
1992021
Necrotic myocardial cells release damage‐associated molecular patterns that provoke fibroblast activation in vitro and trigger myocardial inflammation and fibrosis in vivo
W Zhang, KJ Lavine, S Epelman, SA Evans, CJ Weinheimer, PM Barger, ...
Journal of the American Heart Association 4 (6), e001993, 2015
1912015
The Macrophage in Cardiac Homeostasis and Disease: JACC Macrophage in CVD Series (Part 4)
KJ Lavine, AR Pinto, S Epelman, BJ Kopecky, X Clemente-Casares, ...
Journal of the American College of Cardiology 72 (18), 2213-2230, 2018
1902018
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