The blood–brain barrier R Daneman, A Prat Cold Spring Harbor perspectives in biology 7 (1), a020412, 2015 | 2976 | 2015 |
Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation H Kebir, K Kreymborg, I Ifergan, A Dodelet-Devillers, R Cayrol, M Bernard, ... Nature medicine 13 (10), 1173-1175, 2007 | 2021 | 2007 |
Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor V Rothhammer, ID Mascanfroni, L Bunse, MC Takenaka, JE Kenison, ... Nature medicine 22 (6), 586-597, 2016 | 1204 | 2016 |
The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence JI Alvarez, A Dodelet-Devillers, H Kebir, I Ifergan, PJ Fabre, S Terouz, ... Science 334 (6063), 1727-1731, 2011 | 850 | 2011 |
Preferential recruitment of interferon‐γ–expressing TH17 cells in multiple sclerosis H Kebir, I Ifergan, JI Alvarez, M Bernard, J Poirier, N Arbour, P Duquette, ... Annals of Neurology: Official Journal of the American Neurological …, 2009 | 661 | 2009 |
An updated histological classification system for multiple sclerosis lesions T Kuhlmann, S Ludwin, A Prat, J Antel, W Brück, H Lassmann Acta neuropathologica 133, 13-24, 2017 | 606 | 2017 |
Glial influence on the blood brain barrier JI Alvarez, T Katayama, A Prat Glia 61 (12), 1939-1958, 2013 | 594 | 2013 |
How do immune cells overcome the blood–brain barrier in multiple sclerosis? C Larochelle, JI Alvarez, A Prat FEBS letters 585 (23), 3770-3780, 2011 | 551 | 2011 |
Brain‐immune connection: immuno‐regulatory properties of CNS‐resident cells B Becher, A Prat, JP Antel Glia 29 (4), 293-304, 2000 | 515 | 2000 |
Activated leukocyte cell adhesion molecule promotes leukocyte trafficking into the central nervous system R Cayrol, K Wosik, JL Berard, A Dodelet-Devillers, I Ifergan, H Kebir, ... Nature immunology 9 (2), 137-145, 2008 | 477 | 2008 |
Association of initial disease-modifying therapy with later conversion to secondary progressive multiple sclerosis JWL Brown, A Coles, D Horakova, E Havrdova, G Izquierdo, A Prat, ... Jama 321 (2), 175-187, 2019 | 474 | 2019 |
Regulation of astrocyte activation by glycolipids drives chronic CNS inflammation L Mayo, SA Trauger, M Blain, M Nadeau, B Patel, JI Alvarez, ... Nature medicine 20 (10), 1147-1156, 2014 | 438 | 2014 |
Glial cell influence on the human blood‐brain barrier A Prat, K Biernacki, K Wosik, JP Antel Glia 36 (2), 145-155, 2001 | 429 | 2001 |
Proinflammatory GM-CSF–producing B cells in multiple sclerosis and B cell depletion therapy R Li, A Rezk, Y Miyazaki, E Hilgenberg, H Touil, P Shen, CS Moore, ... Science translational medicine 7 (310), 310ra166-310ra166, 2015 | 417 | 2015 |
Defining secondary progressive multiple sclerosis J Lorscheider, K Buzzard, V Jokubaitis, T Spelman, E Havrdova, ... Brain 139 (9), 2395-2405, 2016 | 401 | 2016 |
Disruption of central nervous system barriers in multiple sclerosis JI Alvarez, R Cayrol, A Prat Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1812 (2), 252-264, 2011 | 392 | 2011 |
Control of tumor-associated macrophages and T cells in glioblastoma via AHR and CD39 MC Takenaka, G Gabriely, V Rothhammer, ID Mascanfroni, MA Wheeler, ... Nature neuroscience 22 (5), 729-740, 2019 | 389 | 2019 |
Immunologic privilege in the central nervous system and the blood–brain barrier LL Muldoon, JI Alvarez, DJ Begley, RJ Boado, GJ Del Zoppo, ND Doolittle, ... Journal of Cerebral Blood Flow & Metabolism 33 (1), 13-21, 2013 | 347 | 2013 |
MAFG-driven astrocytes promote CNS inflammation MA Wheeler, IC Clark, EC Tjon, Z Li, SEJ Zandee, CP Couturier, ... Nature 578 (7796), 593-599, 2020 | 341 | 2020 |
Transcriptome analysis reveals nonfoamy rather than foamy plaque macrophages are proinflammatory in atherosclerotic murine models K Kim, D Shim, JS Lee, K Zaitsev, JW Williams, KW Kim, MY Jang, ... Circulation research 123 (10), 1127-1142, 2018 | 340 | 2018 |