COVID-19: drug targets and potential treatments C Gil, T Ginex, I Maestro, V Nozal, L Barrado-Gil, MÁ Cuesta-Geijo, ... Journal of medicinal chemistry 63 (21), 12359-12386, 2020 | 435 | 2020 |
Is it reliable to take the molecular docking top scoring position as the best solution without considering available structural data? D Ramírez, J Caballero Molecules 23 (5), 1038, 2018 | 428 | 2018 |
Is It Reliable to Use Common Molecular Docking Methods for Comparing the Binding Affinities of Enantiomer Pairs for Their Protein Target? D Ramírez, J Caballero International Journal of Molecular Sciences 17 (525), 2016 | 161 | 2016 |
Origin and evolution of transporter substrate specificity within the NPF family ME Jørgensen, D Xu, C Crocoll, HA Ernst, D Ramírez, MS Motawia, ... Elife 6, e19466, 2017 | 91 | 2017 |
Kv1. 5 blockers preferentially inhibit TASK-1 channels: TASK-1 as a target against atrial fibrillation and obstructive sleep apnea? AK Kiper, S Rinné, C Rolfes, D Ramírez, G Seebohm, MF Netter, ... Pflügers Archiv-European Journal of Physiology 467, 1081-1090, 2015 | 70 | 2015 |
Computational methods applied to rational drug design D Ramírez The Open Medicinal Chemistry Journal 10, 7, 2016 | 63 | 2016 |
Conotoxins as Tools to Understand the Physiological Function of Voltage-Gated Calcium (CaV) Channels D Ramírez, W Gonzalez, RA Fissore, I Carvacho Marine drugs 15 (10), 313, 2017 | 50 | 2017 |
Novel alkylimidazolium ionic liquids as an antibacterial alternative to pathogens of the skin and soft tissue infections O Forero Doria, R Castro, M Gutierrez, D Gonzalez Valenzuela, L Santos, ... Molecules 23 (9), 2354, 2018 | 49 | 2018 |
CoaTx-II, a new dimeric Lys49 phospholipase A2 from Crotalus oreganus abyssus snake venom with bactericidal potential: Insights into its structure and biological roles JR Almeida, M Lancellotti, AM Soares, LA Calderón, D Ramírez, ... Toxicon 120, 147-158, 2016 | 48 | 2016 |
Novel N‐allyl/propargyl tetrahydroquinolines: Synthesis via Three‐component Cationic Imino Diels–Alder Reaction, Binding Prediction, and Evaluation as … YA Rodríguez, M Gutiérrez, D Ramírez, J Alzate‐Morales, CC Bernal, ... Chemical biology & drug design 88 (4), 498-510, 2016 | 43 | 2016 |
HCN channels: new therapeutic targets for pain treatment D Ramírez, R Zúñiga, G Concha, L Zúñiga Molecules 23 (9), 2094, 2018 | 40 | 2018 |
Targeting nuclear protein TDP-43 by cell division cycle kinase 7 inhibitors: A new therapeutic approach for amyotrophic lateral sclerosis E Rojas-Prats, L Martinez-Gonzalez, C Gonzalo-Consuegra, NF Liachko, ... European Journal of Medicinal Chemistry 210, 112968, 2021 | 39 | 2021 |
Computational studies of snake venom toxins PG Ojeda, D Ramírez, J Alzate-Morales, J Caballero, Q Kaas, ... Toxins 10 (1), 8, 2017 | 39 | 2017 |
TDP-43 modulation by tau-tubulin kinase 1 inhibitors: A new avenue for future amyotrophic lateral sclerosis therapy V Nozal, L Martínez-González, M Gomez-Almeria, C Gonzalo-Consuegra, ... Journal of Medicinal Chemistry 65 (2), 1585-1607, 2022 | 31 | 2022 |
The interplay of the metallosensor CueR with two distinct CopZ chaperones defines copper homeostasis in Pseudomonas aeruginosa L Novoa-Aponte, D Ramírez, JM Argüello Journal of Biological Chemistry 294 (13), 4934-4945, 2019 | 30 | 2019 |
K2P channels in plants and animals W González, B Valdebenito, J Caballero, G Riadi, J Riedelsberger, ... Pflügers Archiv-European Journal of Physiology 467, 1091-1104, 2015 | 29 | 2015 |
Host-directed FDA-approved drugs with antiviral activity against SARS-CoV-2 identified by hierarchical in silico/in vitro screening methods T Ginex, U Garaigorta, D Ramírez, V Castro, V Nozal, I Maestro, ... Pharmaceuticals 14 (4), 332, 2021 | 27 | 2021 |
From kinase inhibitors to multitarget ligands as powerful drug leads for Alzheimer's disease using protein‐templated synthesis V Nozal, A García‐Rubia, EP Cuevas, C Pérez, C Tosat‐Bitrián, ... Angewandte Chemie 133 (35), 19493-19503, 2021 | 25 | 2021 |
The molecular basis for an allosteric inhibition of K+-flux gating in K2P channels S Rinne, AK Kiper, KS Vowinkel, D Ramírez, M Schewe, M Bedoya, ... Elife 8, e39476, 2019 | 25 | 2019 |
Side Fenestrations Provide an “anchor” for a Stable Binding of A1899 to the Pore of TASK-1 Potassium Channels D Ramírez, B Arévalo, G Martínez, S Rinné, FV Sepúlveda, N Decher, ... Molecular Pharmaceutics 14 (7), 2197-2208, 2017 | 22 | 2017 |