Living with heterogeneities in bioreactors: understanding the effects of environmental gradients on cells AR Lara, E Galindo, OT Ramírez, LA Palomares Molecular biotechnology 34 (3), 355-381, 2006 | 444 | 2006 |
Replacement of the glucose phosphotransferase transport system by galactose permease reduces acetate accumulation and improves process performance of Escherichia coli for … R De Anda, AR Lara, V Hernández, V Hernández-Montalvo, G Gosset, ... Metabolic engineering 8 (3), 281-290, 2006 | 167 | 2006 |
Metabolic variability in bioprocessing: implications of microbial phenotypic heterogeneity F Delvigne, Q Zune, AR Lara, W Al-Soud, SJ Sørensen Trends in Biotechnology 32 (12), 608-616, 2014 | 127 | 2014 |
Transcriptional and metabolic response of recombinant Escherichia coli to spatial dissolved oxygen tension gradients simulated in a scale‐down system AR Lara, L Leal, N Flores, G Gosset, F Bolívar, OT Ramírez Biotechnology and bioengineering 93 (2), 372-385, 2006 | 114 | 2006 |
Utility of an Escherichia coli strain engineered in the substrate uptake system for improved culture performance at high glucose and cell concentrations: An … AR Lara, L Caspeta, G Gosset, F Bolívar, OT Ramírez Biotechnology and bioengineering 99 (4), 893-901, 2008 | 91 | 2008 |
Producción de proteínas recombinantes en Escherichia coli ÁR Lara Revista mexicana de ingeniería química 10 (2), 209-223, 2011 | 89* | 2011 |
Fast dynamic response of the fermentative metabolism of Escherichia coli to aerobic and anaerobic glucose pulses AR Lara, H Taymaz‐Nikerel, MR Mashego, WM Van Gulik, JJ Heijnen, ... Biotechnology and Bioengineering 104 (6), 1153-1161, 2009 | 88 | 2009 |
Engineering Escherichia coli to increase plasmid DNA production in high cell-density cultivations in batch mode GM Borja, E Meza Mora, B Barrón, G Gosset, OT Ramírez, AR Lara Microbial Cell Factories 11, 1-9, 2012 | 84 | 2012 |
Metabolic Engineering of Escherichia coli for l-Tyrosine Production by Expression of Genes Coding for the Chorismate Mutase Domain of the Native Chorismate Mutase … MI Chavez-Bejar, AR Lara, H Lopez, G Hernández-Chávez, A Martinez, ... Applied and Environmental Microbiology 74 (10), 3284-3290, 2008 | 73 | 2008 |
High cell-density processes in batch mode of a genetically engineered Escherichia coli strain with minimized overflow metabolism using a pressurized bioreactor I Knabben, L Regestein, F Marquering, S Steinbusch, AR Lara, J Büchs Journal of biotechnology 150 (1), 73-79, 2010 | 68 | 2010 |
Plasmid DNA production for therapeutic applications AR Lara, OT Ramírez Recombinant Gene Expression, 271-303, 2012 | 67 | 2012 |
Engineering Escherichia coli to improve culture performance and reduce formation of by‐products during recombinant protein production under transient intermittent anaerobic … AR Lara, C Vazquez‐Limón, G Gosset, F Bolívar, A López‐Munguía, ... Biotechnology and bioengineering 94 (6), 1164-1175, 2006 | 63 | 2006 |
Modification of glucose import capacity in Escherichia coli: physiologic consequences and utility for improving DNA vaccine production LG Fuentes, AR Lara, LM Martínez, OT Ramírez, A Martínez, F Bolívar, ... Microbial cell factories 12, 1-11, 2013 | 50 | 2013 |
Aerobic expression of Vitreoscilla hemoglobin efficiently reduces overflow metabolism in Escherichia coli TE Pablos, JC Sigala, S Le Borgne, AR Lara Biotechnology journal 9 (6), 791-799, 2014 | 38 | 2014 |
High cell-density cultivation in batch mode for plasmid DNA production by a metabolically engineered E. coli strain with minimized overflow metabolism R Soto, L Caspeta, B Barrón, G Gosset, OT Ramírez, AR Lara Biochemical engineering journal 56 (3), 165-171, 2011 | 38 | 2011 |
Comparison of oxygen enriched air vs. pressure cultivations to increase oxygen transfer and to scale‐up plasmid DNA production fermentations AR Lara, I Knabben, L Regestein, J Sassi, L Caspeta, OT Ramírez, ... Engineering in Life Sciences 11 (4), 382-386, 2011 | 36 | 2011 |
Effect of growth rate on plasmid DNA production and metabolic performance of engineered Escherichia coli strains M Wunderlich, H Taymaz-Nikerel, G Gosset, OT Ramírez, AR Lara Journal of bioscience and bioengineering 117 (3), 336-342, 2014 | 35 | 2014 |
Bioreactor scale‐down LA Palomares, AR Lara, OT RamÍRez Encyclopedia of industrial biotechnology: bioprocess, bioseparation, and …, 2009 | 35 | 2009 |
Characterization of Endogenous and Reduced Promoters for Oxygen-Limited Processes Using Escherichia coli AR Lara, KE Jaén, JC Sigala, M Mühlmann, L Regestein, J Büchs ACS synthetic biology 6 (2), 344-356, 2017 | 29 | 2017 |
Microbial population heterogeneity versus bioreactor heterogeneity: evaluation of Redox Sensor Green as an exogenous metabolic biosensor J Baert, A Delepierre, S Telek, P Fickers, D Toye, A Delamotte, AR Lara, ... Engineering in Life Sciences 16 (7), 643-651, 2016 | 29 | 2016 |