Targeted therapeutics and novel signaling pathways in non-alcohol-associated fatty liver/steatohepatitis (NAFL/NASH) X Xu, KL Poulsen, L Wu, S Liu, T Miyata, Q Song, Q Wei, C Zhao, C Lin, ... Signal transduction and targeted therapy 7 (1), 287, 2022 | 131 | 2022 |
MLKL-dependent signaling regulates autophagic flux in a murine model of non-alcohol-associated fatty liver and steatohepatitis X Wu, KL Poulsen, C Sanz-Garcia, E Huang, MR McMullen, ... Journal of hepatology 73 (3), 616-627, 2020 | 116 | 2020 |
Hepatocyte-derived macrophage migration inhibitory factor mediates alcohol-induced liver injury in mice and patients V Marin, K Poulsen, G Odena, MR McMullen, J Altamirano, P Sancho-Bru, ... Journal of hepatology 67 (5), 1018-1025, 2017 | 65 | 2017 |
Effect of acid suppressants on the risk of COVID-19: a propensity score-matched study using UK Biobank X Fan, Z Liu, T Miyata, S Dasarathy, DM Rotroff, X Wu, KL Poulsen, ... Gastroenterology 160 (1), 455, 2021 | 42 | 2021 |
Complement Factor D protects mice from ethanol-induced inflammation and liver injury RL McCullough, MR McMullen, MM Sheehan, KL Poulsen, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 315 (1 …, 2018 | 40 | 2018 |
Hepatic recruitment of eosinophils and their protective function during acute liver injury L Xu, Y Yang, Y Wen, JM Jeong, C Emontzpohl, CL Atkins, Z Sun, ... Journal of hepatology 77 (2), 344-352, 2022 | 38 | 2022 |
The non-transcriptional activity of IRF3 modulates hepatic immune cell populations in acute-on-chronic ethanol administration in mice C Sanz-Garcia, KL Poulsen, D Bellos, H Wang, MR McMullen, X Li, ... Journal of hepatology 70 (5), 974-984, 2019 | 36 | 2019 |
Trovafloxacin enhances lipopolysaccharide-stimulated production of tumor necrosis factor-α by macrophages: role of the DNA damage response KL Poulsen, J Olivero-Verbel, KM Beggs, PE Ganey, RA Roth Journal of Pharmacology and Experimental Therapeutics 350 (1), 164-170, 2014 | 32 | 2014 |
Gut microbial trimethylamine is elevated in alcohol-associated hepatitis and contributes to ethanol-induced liver injury in mice RN Helsley, T Miyata, A Kadam, V Varadharajan, N Sangwan, EC Huang, ... Elife 11, e76554, 2022 | 27 | 2022 |
Inhibition of IRAK4 kinase activity improves ethanol-induced liver injury in mice H Wang, H Zhou, Q Zhang, KL Poulsen, V Taylor, MR McMullen, ... Journal of hepatology 73 (6), 1470-1481, 2020 | 27 | 2020 |
Alcohol consumption is associated with poor prognosis in obese patients with COVID-19: a Mendelian randomization study using UK Biobank X Fan, Z Liu, KL Poulsen, X Wu, T Miyata, S Dasarathy, DM Rotroff, ... Nutrients 13 (5), 1592, 2021 | 25 | 2021 |
Anaphylatoxin receptors C3aR and C5aR1 are important factors that influence the impact of ethanol on the adipose secretome RL McCullough, MR McMullen, KL Poulsen, A Kim, ME Medof, LE Nagy Frontiers in Immunology 9, 2133, 2018 | 25 | 2018 |
Novel role of macrophage migration inhibitory factor in upstream control of the unfolded protein response after ethanol feeding in mice KL Poulsen, MR McMullen, E Huang, CD Kibler, MM Sheehan, L Leng, ... Alcoholism: Clinical and Experimental Research 43 (7), 1439-1451, 2019 | 24 | 2019 |
Trovafloxacin-induced replication stress sensitizes HepG2 cells to tumor necrosis factor-alpha-induced cytotoxicity mediated by extracellular signal-regulated kinase and ataxia … KM Beggs, AR Maiuri, AM Fullerton, KL Poulsen, AB Breier, PE Ganey, ... Toxicology 331, 35-46, 2015 | 24 | 2015 |
Diagnostic and prognostic significance of complement in patients with alcohol‐associated hepatitis X Fan, RL McCullough, E Huang, A Bellar, A Kim, KL Poulsen, ... Hepatology 73 (3), 983-997, 2021 | 21 | 2021 |
Trovafloxacin potentiation of lipopolysaccharide-induced tumor necrosis factor release from RAW 264.7 cells requires extracellular signal-regulated kinase and c-Jun N-Terminal … KL Poulsen, RP Albee, PE Ganey, RA Roth Journal of Pharmacology and Experimental Therapeutics 349 (2), 185-191, 2014 | 19 | 2014 |
Radiofrequency ablation remodels the tumor microenvironment and promotes neutrophil-mediated abscopal immunomodulation in pancreatic cancer EY Faraoni, BJ O'Brien, LN Strickland, BK Osborn, V Mota, J Chaney, ... Cancer immunology research 11 (1), 4-12, 2023 | 17 | 2023 |
CD73-dependent adenosine signaling through Adora2b drives immunosuppression in ductal pancreatic cancer EY Faraoni, K Singh, V Chandra, O Le Roux, Y Dai, I Sahin, BJ O'Brien, ... Cancer research 83 (7), 1111-1127, 2023 | 12 | 2023 |
The effects of obesity and metabolic abnormalities on severe COVID-19-related outcomes after vaccination: A population-based study X Fan, J Han, E Zhao, J Fang, D Wang, Y Cheng, Y Shi, Z Wang, Z Yao, ... Cell Metabolism 35 (4), 585-600. e5, 2023 | 10 | 2023 |
Role of the chemokine system in liver fibrosis: a narrative review KL Poulsen, CK Cajigas-Du Ross, JK Chaney, LE Nagy Digestive medicine research 5, 2022 | 10 | 2022 |