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Tom N. Grossmann
Tom N. Grossmann
Professor of Biomimetic Chemistry, Vrije Universiteit Amsterdam
在 vu.nl 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Structure‐based design of inhibitors of protein–protein interactions: mimicking peptide binding epitopes
M Pelay‐Gimeno, A Glas, O Koch, TN Grossmann
Angewandte Chemie International Edition 54 (31), 8896-8927, 2015
7122015
Modulators of protein–protein interactions
LG Milroy, TN Grossmann, S Hennig, L Brunsveld, C Ottmann
Chemical reviews 114 (9), 4695-4748, 2014
4972014
Synthesis of all-hydrocarbon stapled α-helical peptides by ring-closing olefin metathesis
YW Kim, TN Grossmann, GL Verdine
Nature protocols 6 (6), 761-771, 2011
4432011
New modalities for challenging targets in drug discovery
E Valeur, SM Guéret, H Adihou, R Gopalakrishnan, M Lemurell, ...
Angewandte Chemie International Edition 56 (35), 10294-10323, 2017
3582017
Hydrocarbon stapled peptides as modulators of biological function
PM Cromm, J Spiegel, TN Grossmann
ACS chemical biology 10 (6), 1362-1375, 2015
2942015
Inhibition of oncogenic Wnt signaling through direct targeting of β-catenin
TN Grossmann, JTH Yeh, BR Bowman, Q Chu, RE Moellering, ...
Proceedings of the National Academy of Sciences 109 (44), 17942-17947, 2012
2872012
Small-molecule modulation of Ras signaling
J Spiegel, PM Cromm, G Zimmermann, TN Grossmann, H Waldmann
Nature chemical biology 10 (8), 613-622, 2014
2692014
Towards understanding cell penetration by stapled peptides
Q Chu, RE Moellering, GJ Hilinski, YW Kim, TN Grossmann, JTH Yeh, ...
MedChemComm 6 (1), 111-119, 2015
2612015
Plant cysteine oxidases are dioxygenases that directly enable arginyl transferase-catalysed arginylation of N-end rule targets
MD White, M Klecker, RJ Hopkinson, DA Weits, C Mueller, C Naumann, ...
Nature communications 8 (1), 14690, 2017
1902017
DNA-catalyzed transfer of a reporter group
TN Grossmann, O Seitz
Journal of the American Chemical Society 128 (49), 15596-15597, 2006
1602006
Constrained peptides with target‐adapted cross‐links as inhibitors of a pathogenic protein–protein interaction
A Glas, D Bier, G Hahne, C Rademacher, C Ottmann, TN Grossmann
Angewandte Chemie International Edition 53 (9), 2489-2493, 2014
1562014
Triplex molecular beacons as modular probes for DNA detection
TN Grossmann, L Röglin, O Seitz
Angewandte Chemie International Edition 46 (27), 5223-5225, 2007
1442007
Bifunctional stapled polypeptides and uses thereof
GL Verdine, TN Grossmann, RE Moellering, THJ Yeh, YRY Liang, Y Oak
US Patent 9,163,330, 2015
1352015
Achieving turnover in DNA‐templated reactions
TN Grossmann, A Strohbach, O Seitz
ChemBioChem 9 (14), 2185-2192, 2008
1322008
Cell permeable stapled peptide inhibitor of Wnt signaling that targets β-catenin protein-protein interactions
L Dietrich, B Rathmer, K Ewan, T Bange, S Heinrichs, TC Dale, D Schade, ...
Cell chemical biology 24 (8), 958-968. e5, 2017
1202017
Proteomimetics as protein-inspired scaffolds with defined tertiary folding patterns
WS Horne, TN Grossmann
Nature chemistry 12 (4), 331-337, 2020
1142020
Direct Targeting of Rab‐GTPase–Effector Interactions
J Spiegel, PM Cromm, A Itzen, RS Goody, TN Grossmann, H Waldmann
Angewandte Chemie International Edition 53 (9), 2498-2503, 2014
1042014
Orthogonal ring-closing alkyne and olefin metathesis for the synthesis of small GTPase-targeting bicyclic peptides
PM Cromm, S Schaubach, J Spiegel, A Fürstner, TN Grossmann, ...
Nature communications 7 (1), 11300, 2016
1032016
Nucleic acid templated reactions: consequences of probe reactivity and readout strategy for amplified signaling and sequence selectivity
TN Grossmann, O Seitz
Chemistry–A European Journal 15 (27), 6723-6730, 2009
882009
Reversible covalent inhibition of a protein target
CU Lee, TN Grossmann
Angewandte Chemie International Edition 35 (51), 8699-8700, 2012
852012
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