Activation of proto-oncogenes by disruption of chromosome neighborhoods D Hnisz, AS Weintraub, DS Day, AL Valton, RO Bak, CH Li, J Goldmann, ... Science 351 (6280), 1454-1458, 2016 | 1085 | 2016 |
Systematic identification of culture conditions for induction and maintenance of naive human pluripotency TW Theunissen, BE Powell, H Wang, M Mitalipova, DA Faddah, J Reddy, ... Cell stem cell 15 (4), 471-487, 2014 | 970 | 2014 |
Control of cell identity genes occurs in insulated neighborhoods in mammalian chromosomes JM Dowen, ZP Fan, D Hnisz, G Ren, BJ Abraham, LN Zhang, ... Cell 159 (2), 374-387, 2014 | 945 | 2014 |
3D chromosome regulatory landscape of human pluripotent cells X Ji, DB Dadon, BE Powell, ZP Fan, D Borges-Rivera, S Shachar, ... Cell stem cell 18 (2), 262-275, 2016 | 442 | 2016 |
A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation CK Kaufman, C Mosimann, ZP Fan, S Yang, AJ Thomas, J Ablain, JL Tan, ... Science 351 (6272), aad2197, 2016 | 399 | 2016 |
Lineage regulators direct BMP and Wnt pathways to cell-specific programs during differentiation and regeneration E Trompouki, TV Bowman, LN Lawton, ZP Fan, DC Wu, A DiBiase, ... Cell 147 (3), 577-589, 2011 | 363 | 2011 |
Core transcriptional regulatory circuit controlled by the TAL1 complex in human T cell acute lymphoblastic leukemia T Sanda, LN Lawton, MI Barrasa, ZP Fan, H Kohlhammer, A Gutierrez, ... Cancer cell 22 (2), 209-221, 2012 | 355 | 2012 |
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells KA Lawson, CM Sousa, X Zhang, E Kim, R Akthar, JJ Caumanns, Y Yao, ... Nature 586 (7827), 120-126, 2020 | 301 | 2020 |
Single-molecule mRNA detection and counting in mammalian tissue A Lyubimova, S Itzkovitz, JP Junker, ZP Fan, X Wu, A Van Oudenaarden Nature protocols 8 (9), 1743-1758, 2013 | 213 | 2013 |
Genome-wide localization of small molecules L Anders, MG Guenther, J Qi, ZP Fan, JJ Marineau, PB Rahl, J Loven, ... Nature biotechnology 32 (1), 92-96, 2014 | 191 | 2014 |
A systematic approach to identify candidate transcription factors that control cell identity AC D’Alessio, ZP Fan, KJ Wert, P Baranov, MA Cohen, JS Saini, E Cohick, ... Stem cell reports 5 (5), 763-775, 2015 | 174 | 2015 |
Selective HDAC1/HDAC2 inhibitors induce neuroblastoma differentiation SM Frumm, ZP Fan, KN Ross, JR Duvall, S Gupta, L VerPlank, BC Suh, ... Chemistry & biology 20 (5), 713-725, 2013 | 114 | 2013 |
Nanog-like regulates endoderm formation through the Mxtx2-Nodal pathway C Xu, ZP Fan, P Müller, R Fogley, A DiBiase, E Trompouki, ... Developmental cell 22 (3), 625-638, 2012 | 104 | 2012 |
The rate of protein synthesis in hematopoietic stem cells is limited partly by 4E-BPs RAJ Signer, L Qi, Z Zhao, D Thompson, AA Sigova, ZP Fan, ... Genes & development 30 (15), 1698-1703, 2016 | 99 | 2016 |
Stress from nucleotide depletion activates the transcriptional regulator HEXIM1 to suppress melanoma JL Tan, RD Fogley, RA Flynn, J Ablain, S Yang, V Saint-André, ZP Fan, ... Molecular cell 62 (1), 34-46, 2016 | 81 | 2016 |
Catalytic and stereoselective iodination of prochiral C–H bonds R Giri, X Chen, XS Hao, JJ Li, J Liang, ZP Fan, JQ Yu Tetrahedron: Asymmetry 16 (21), 3502-3505, 2005 | 79 | 2005 |
Direct lineage conversion of adult mouse liver cells and B lymphocytes to neural stem cells JP Cassady, AC D’Alessio, S Sarkar, VS Dani, ZP Fan, K Ganz, ... Stem cell reports 3 (6), 948-956, 2014 | 73 | 2014 |
A chemical biology screen identifies a vulnerability of neuroendocrine cancer cells to SQLE inhibition CE Mahoney, D Pirman, V Chubukov, T Sleger, S Hayes, ZP Fan, ... Nature communications 10 (1), 96, 2019 | 72 | 2019 |
Differential aspartate usage identifies a subset of cancer cells particularly dependent on OGDH EL Allen, DB Ulanet, D Pirman, CE Mahoney, J Coco, Y Si, Y Chen, ... Cell reports 17 (3), 876-890, 2016 | 68 | 2016 |
Picometer-scale conformational heterogeneity separates functional from nonfunctional states of a photoreceptor protein PD Coureux, ZP Fan, V Stojanoff, UK Genick Structure 16 (6), 863-872, 2008 | 26 | 2008 |