Patient-derived tumour xenografts as models for oncology drug development JJ Tentler, AC Tan, CD Weekes, A Jimeno, S Leong, TM Pitts, JJ Arcaroli, ... Nature reviews Clinical oncology 9 (6), 338-350, 2012 | 1393 | 2012 |
Caspase 3–mediated stimulation of tumor cell repopulation during cancer radiotherapy Q Huang, F Li, X Liu, W Li, W Shi, FF Liu, B O'sullivan, Z He, Y Peng, ... Nature medicine 17 (7), 860-866, 2011 | 921 | 2011 |
Ensemble machine learning on gene expression data for cancer classification AC Tan, D Gilbert University of Glasgow, 2003 | 579 | 2003 |
A DNA methylation fingerprint of 1628 human samples AF Fernandez, Y Assenov, JI Martin-Subero, B Balint, R Siebert, ... Genome research 22 (2), 407-419, 2012 | 476 | 2012 |
Simple decision rules for classifying human cancers from gene expression profiles AC Tan, DQ Naiman, L Xu, RL Winslow, D Geman Bioinformatics 21 (20), 3896-3904, 2005 | 474 | 2005 |
Genetic analysis of 779 advanced differentiated and anaplastic thyroid cancers N Pozdeyev, LM Gay, ES Sokol, R Hartmaier, KE Deaver, S Davis, ... Clinical Cancer Research 24 (13), 3059-3068, 2018 | 467 | 2018 |
Optimizing the detection of lung cancer patients harboring anaplastic lymphoma kinase (ALK) gene rearrangements potentially suitable for ALK inhibitor treatment DR Camidge, SA Kono, A Flacco, AC Tan, RC Doebele, Q Zhou, L Crino, ... Clinical Cancer Research 16 (22), 5581-5590, 2010 | 427 | 2010 |
Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2 TR Lyons, J O'brien, VF Borges, MW Conklin, PJ Keely, KW Eliceiri, ... Nature medicine 17 (9), 1109-1115, 2011 | 390 | 2011 |
DSigDB: drug signatures database for gene set analysis M Yoo, J Shin, J Kim, KA Ryall, K Lee, S Lee, M Jeon, J Kang, AC Tan Bioinformatics 31 (18), 3069-3071, 2015 | 372 | 2015 |
The miR-106b-25 cluster targets Smad7, activates TGF-β signaling, and induces EMT and tumor initiating cell characteristics downstream of Six1 in human breast cancer AL Smith, R Iwanaga, DJ Drasin, DS Micalizzi, RL Vartuli, AC Tan, ... Oncogene 31 (50), 5162-5171, 2012 | 363 | 2012 |
Tumor engraftment in nude mice and enrichment in stroma-related gene pathways predict poor survival and resistance to gemcitabine in patients with pancreatic cancer I Garrido-Laguna, M Uson, NV Rajeshkumar, AC Tan, E De Oliveira, ... Clinical Cancer Research 17 (17), 5793-5800, 2011 | 271 | 2011 |
A mechanism of resistance to gefitinib mediated by cellular reprogramming and the acquisition of an FGF2-FGFR1 autocrine growth loop KE Ware, TK Hinz, E Kleczko, KR Singleton, LA Marek, BA Helfrich, ... Oncogenesis 2 (3), e39-e39, 2013 | 254 | 2013 |
AMPK/FIS1-mediated mitophagy is required for self-renewal of human AML stem cells S Pei, M Minhajuddin, B Adane, N Khan, BM Stevens, SC Mack, S Lai, ... Cell stem cell 23 (1), 86-100. e6, 2018 | 230 | 2018 |
Resistance to radiotherapy and PD-L1 blockade is mediated by TIM-3 upregulation and regulatory T-cell infiltration A Oweida, MK Hararah, A Phan, D Binder, S Bhatia, S Lennon, ... Clinical Cancer Research 24 (21), 5368-5380, 2018 | 225 | 2018 |
Plasma-based circulating MicroRNA biomarkers for Parkinson's disease SK Khoo, D Petillo, UJ Kang, JH Resau, B Berryhill, J Linder, L Forsgren, ... Journal of Parkinson's disease 2 (4), 321-331, 2012 | 219 | 2012 |
Direct reprogramming of human fibroblasts into dopaminergic neuron-like cells X Liu, F Li, EA Stubblefield, B Blanchard, TL Richards, GA Larson, Y He, ... Cell research 22 (2), 321-332, 2012 | 217 | 2012 |
Fibroblast subtypes regulate responsiveness of luminal breast cancer to estrogen HM Brechbuhl, J Finlay-Schultz, TM Yamamoto, AE Gillen, DM Cittelly, ... Clinical Cancer Research 23 (7), 1710-1721, 2017 | 214 | 2017 |
GSEA-InContext: identifying novel and common patterns in expression experiments RK Powers, A Goodspeed, H Pielke-Lombardo, AC Tan, JC Costello Bioinformatics 34 (13), i555-i564, 2018 | 186 | 2018 |
Characterizing DNA methylation patterns in pancreatic cancer genome AC Tan, A Jimeno, SH Lin, J Wheelhouse, F Chan, A Solomon, ... Molecular oncology 3 (5-6), 425-438, 2009 | 186 | 2009 |
Multi-class protein fold classification using a new ensemble machine learning approach AC Tan, D Gilbert, Y Deville Genome Informatics 14, 206-217, 2003 | 178 | 2003 |