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Aik Choon Tan
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Patient-derived tumour xenografts as models for oncology drug development
JJ Tentler, AC Tan, CD Weekes, A Jimeno, S Leong, TM Pitts, JJ Arcaroli, ...
Nature reviews Clinical oncology 9 (6), 338-350, 2012
13932012
Caspase 3–mediated stimulation of tumor cell repopulation during cancer radiotherapy
Q Huang, F Li, X Liu, W Li, W Shi, FF Liu, B O'sullivan, Z He, Y Peng, ...
Nature medicine 17 (7), 860-866, 2011
9212011
Ensemble machine learning on gene expression data for cancer classification
AC Tan, D Gilbert
University of Glasgow, 2003
5792003
A DNA methylation fingerprint of 1628 human samples
AF Fernandez, Y Assenov, JI Martin-Subero, B Balint, R Siebert, ...
Genome research 22 (2), 407-419, 2012
4762012
Simple decision rules for classifying human cancers from gene expression profiles
AC Tan, DQ Naiman, L Xu, RL Winslow, D Geman
Bioinformatics 21 (20), 3896-3904, 2005
4742005
Genetic analysis of 779 advanced differentiated and anaplastic thyroid cancers
N Pozdeyev, LM Gay, ES Sokol, R Hartmaier, KE Deaver, S Davis, ...
Clinical Cancer Research 24 (13), 3059-3068, 2018
4672018
Optimizing the detection of lung cancer patients harboring anaplastic lymphoma kinase (ALK) gene rearrangements potentially suitable for ALK inhibitor treatment
DR Camidge, SA Kono, A Flacco, AC Tan, RC Doebele, Q Zhou, L Crino, ...
Clinical Cancer Research 16 (22), 5581-5590, 2010
4272010
Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2
TR Lyons, J O'brien, VF Borges, MW Conklin, PJ Keely, KW Eliceiri, ...
Nature medicine 17 (9), 1109-1115, 2011
3902011
DSigDB: drug signatures database for gene set analysis
M Yoo, J Shin, J Kim, KA Ryall, K Lee, S Lee, M Jeon, J Kang, AC Tan
Bioinformatics 31 (18), 3069-3071, 2015
3722015
The miR-106b-25 cluster targets Smad7, activates TGF-β signaling, and induces EMT and tumor initiating cell characteristics downstream of Six1 in human breast cancer
AL Smith, R Iwanaga, DJ Drasin, DS Micalizzi, RL Vartuli, AC Tan, ...
Oncogene 31 (50), 5162-5171, 2012
3632012
Tumor engraftment in nude mice and enrichment in stroma-related gene pathways predict poor survival and resistance to gemcitabine in patients with pancreatic cancer
I Garrido-Laguna, M Uson, NV Rajeshkumar, AC Tan, E De Oliveira, ...
Clinical Cancer Research 17 (17), 5793-5800, 2011
2712011
A mechanism of resistance to gefitinib mediated by cellular reprogramming and the acquisition of an FGF2-FGFR1 autocrine growth loop
KE Ware, TK Hinz, E Kleczko, KR Singleton, LA Marek, BA Helfrich, ...
Oncogenesis 2 (3), e39-e39, 2013
2542013
AMPK/FIS1-mediated mitophagy is required for self-renewal of human AML stem cells
S Pei, M Minhajuddin, B Adane, N Khan, BM Stevens, SC Mack, S Lai, ...
Cell stem cell 23 (1), 86-100. e6, 2018
2302018
Resistance to radiotherapy and PD-L1 blockade is mediated by TIM-3 upregulation and regulatory T-cell infiltration
A Oweida, MK Hararah, A Phan, D Binder, S Bhatia, S Lennon, ...
Clinical Cancer Research 24 (21), 5368-5380, 2018
2252018
Plasma-based circulating MicroRNA biomarkers for Parkinson's disease
SK Khoo, D Petillo, UJ Kang, JH Resau, B Berryhill, J Linder, L Forsgren, ...
Journal of Parkinson's disease 2 (4), 321-331, 2012
2192012
Direct reprogramming of human fibroblasts into dopaminergic neuron-like cells
X Liu, F Li, EA Stubblefield, B Blanchard, TL Richards, GA Larson, Y He, ...
Cell research 22 (2), 321-332, 2012
2172012
Fibroblast subtypes regulate responsiveness of luminal breast cancer to estrogen
HM Brechbuhl, J Finlay-Schultz, TM Yamamoto, AE Gillen, DM Cittelly, ...
Clinical Cancer Research 23 (7), 1710-1721, 2017
2142017
GSEA-InContext: identifying novel and common patterns in expression experiments
RK Powers, A Goodspeed, H Pielke-Lombardo, AC Tan, JC Costello
Bioinformatics 34 (13), i555-i564, 2018
1862018
Characterizing DNA methylation patterns in pancreatic cancer genome
AC Tan, A Jimeno, SH Lin, J Wheelhouse, F Chan, A Solomon, ...
Molecular oncology 3 (5-6), 425-438, 2009
1862009
Multi-class protein fold classification using a new ensemble machine learning approach
AC Tan, D Gilbert, Y Deville
Genome Informatics 14, 206-217, 2003
1782003
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