| Engineered CRISPR–Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing BP Kleinstiver, AA Sousa, RT Walton, YE Tak, JY Hsu, K Clement, ... Nature biotechnology 37 (3), 276-282, 2019 | 584 | 2019 |
| Making sense of GWAS: using epigenomics and genome engineering to understand the functional relevance of SNPs in non-coding regions of the human genome YG Tak, PJ Farnham Epigenetics & chromatin 8, 1-18, 2015 | 376 | 2015 |
| Inducible and multiplex gene regulation using CRISPR–Cpf1-based transcription factors YE Tak, BP Kleinstiver, JK Nuñez, JY Hsu, JE Horng, J Gong, ... Nature methods 14 (12), 1163-1166, 2017 | 209 | 2017 |
| Cell type-specific binding patterns reveal that TCF7L2 can be tethered to the genome by association with GATA3 S Frietze, R Wang, L Yao, YG Tak, Z Ye, M Gaddis, H Witt, PJ Farnham, ... Genome biology 13, 1-18, 2012 | 127 | 2012 |
| Functional annotation of colon cancer risk SNPs L Yao, YG Tak, BP Berman, PJ Farnham Nature communications 5 (1), 5114, 2014 | 126 | 2014 |
| Identification of activated enhancers and linked transcription factors in breast, prostate, and kidney tumors by tracing enhancer networks using epigenetic traits SK Rhie, Y Guo, YG Tak, L Yao, H Shen, GA Coetzee, PW Laird, ... Epigenetics & chromatin 9, 1-17, 2016 | 58 | 2016 |
| Effects on the transcriptome upon deletion of a distal element cannot be predicted by the size of the H3K27Ac peak in human cells YG Tak, Y Hung, L Yao, MR Grimmer, A Do, MS Bhakta, H O'Geen, ... Nucleic acids research 44 (9), 4123-4133, 2016 | 40 | 2016 |
| Enhanced responses to angiogenic cues underlie the pathogenesis of hereditary hemorrhagic telangiectasia 2 EJ Choi, YH Kim, S Choe, YG Tak, EM Garrido-Martin, M Chang, YJ Lee, ... PLoS One 8 (5), e63138, 2013 | 35 | 2013 |
| Augmenting and directing long-range CRISPR-mediated activation in human cells YE Tak, JE Horng, NT Perry, HT Schultz, S Iyer, Q Yao, LS Zou, MJ Aryee, ... Nature methods 18 (9), 1075-1081, 2021 | 21 | 2021 |
| Functional annotation of colon cancer risk SNPs. Nat Commun 5: 5114 L Yao, YG Tak, BP Berman, PJ Farnham | 5 | 2014 |
| Genome-wide functional perturbation of human microsatellite repeats using engineered zinc finger transcription factors YE Tak, G Boulay, L Lee, S Iyer, NT Perry, HT Schultz, SP Garcia, L Broye, ... Cell genomics 2 (4), 2022 | 4 | 2022 |
| CRISPR PERSIST-On enables heritable and fine-tunable human gene activation YE Tak, JY Hsu, J Shih, HT Schultz, IT Nguyen, KC Lam, L Pinello, ... bioRxiv, 2024.04. 26.590475, 2024 | | 2024 |
| Inducible, Tunable, and Multiplex Human Gene Regulation Using CRISPR-Cpf1 YE Tak, B Kleinstiver, JK Joung US Patent App. 18/304,187, 2023 | | 2023 |
| High-resolution CTCF footprinting reveals impact of chromatin state on cohesin extrusion dynamics CE Sept, YE Tak, CG Cerda-Smith, HM Hutchinson, V Goel, M Blanchette, ... bioRxiv, 2023 | | 2023 |
| Systems and Methods for Stable and Heritable Alteration by Precision Editing (SHAPE) JK Joung, L Pinello, J Hsu, J Grunewald, YE Tak, MN Hamid US Patent App. 17/928,105, 2023 | | 2023 |
| Inducible, tunable, and multiplex human gene regulation using CRISPR-Cpf1 YE Tak, B Kleinstiver, JK Joung US Patent 11,667,677, 2023 | | 2023 |
| System and method for activating gene expression JK Joung, YE Tak US Patent App. 17/779,372, 2023 | | 2023 |
| Augmenting and directing long-range CRISPR-mediated activation in human cells (vol 18, pg 1075, 2021) YE Tak, JE Horng, NT Perry, HT Schultz, S Iyer, Q Yao, LS Zou, MJ Aryee, ... NATURE METHODS 19 (7), 899-899, 2022 | | 2022 |
| Author Correction: Augmenting and directing long-range CRISPR-mediated activation in human cells YE Tak, JE Horng, NT Perry, HT Schultz, S Iyer, Q Yao, LS Zou, MJ Aryee, ... Nature methods 19 (7), 899, 2022 | | 2022 |
| Enhancing Genome Editing with Engineered CRISPR Nucleases RT Walton, AA Sousa, MM Welch, YE Tak, JY Hsu, K Clement, JE Horng, ... MOLECULAR THERAPY 27 (4), 104-105, 2019 | | 2019 |
