The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups C Curtis, SP Shah, SF Chin, G Turashvili, OM Rueda, MJ Dunning, ... Nature 486 (7403), 346-352, 2012 | 6037 | 2012 |
Analysis of circulating tumor DNA to monitor metastatic breast cancer SJ Dawson, DWY Tsui, M Murtaza, H Biggs, OM Rueda, SF Chin, ... New England Journal of Medicine 368 (13), 1199-1209, 2013 | 2488 | 2013 |
The clonal and mutational evolution spectrum of primary triple-negative breast cancers SP Shah, A Roth, R Goya, A Oloumi, G Ha, Y Zhao, G Turashvili, J Ding, ... Nature 486 (7403), 395-399, 2012 | 2291 | 2012 |
The somatic mutation profiles of 2,433 breast cancers refine their genomic and transcriptomic landscapes B Pereira, SF Chin, OM Rueda, HKM Vollan, E Provenzano, HA Bardwell, ... Nature communications 7 (1), 1-16, 2016 | 1598 | 2016 |
Progesterone receptor modulates ERα action in breast cancer H Mohammed, IA Russell, R Stark, OM Rueda, TE Hickey, GA Tarulli, ... Nature 523 (7560), 313-317, 2015 | 746 | 2015 |
Interrogating open issues in cancer precision medicine with patient-derived xenografts AT Byrne, DG Alférez, F Amant, D Annibali, J Arribas, AV Biankin, A Bruna, ... Nature Reviews Cancer 17 (4), 254-268, 2017 | 660 | 2017 |
Multifocal clonal evolution characterized using circulating tumour DNA in a case of metastatic breast cancer M Murtaza, SJ Dawson, K Pogrebniak, OM Rueda, E Provenzano, J Grant, ... Nature communications 6 (1), 8760, 2015 | 508 | 2015 |
Quantitative image analysis of cellular heterogeneity in breast tumors complements genomic profiling Y Yuan, H Failmezger, OM Rueda, HR Ali, S Gräf, SF Chin, RF Schwarz, ... Science translational medicine 4 (157), 157ra143-157ra143, 2012 | 465 | 2012 |
A biobank of breast cancer explants with preserved intra-tumor heterogeneity to screen anticancer compounds A Bruna, OM Rueda, W Greenwood, AS Batra, M Callari, RN Batra, ... Cell 167 (1), 260-274. e22, 2016 | 453 | 2016 |
Endogenous purification reveals GREB1 as a key estrogen receptor regulatory factor H Mohammed, C D’Santos, AA Serandour, HR Ali, GD Brown, A Atkins, ... Cell reports 3 (2), 342-349, 2013 | 403 | 2013 |
A new genome‐driven integrated classification of breast cancer and its implications SJ Dawson, OM Rueda, S Aparicio, C Caldas The EMBO journal 32 (5), 617-628, 2013 | 396 | 2013 |
RAD51 foci as a functional biomarker of homologous recombination repair and PARP inhibitor resistance in germline BRCA-mutated breast cancer C Cruz, M Castroviejo-Bermejo, S Gutiérrez-Enríquez, A Llop-Guevara, ... Annals of Oncology 29 (5), 1203-1210, 2018 | 352 | 2018 |
TP53 Mutation Spectrum in Breast Cancer Is Subtype Specific and Has Distinct Prognostic Relevance L Silwal-Pandit, HKM Vollan, SF Chin, OM Rueda, S McKinney, T Osako, ... Clinical Cancer Research 20 (13), 3569-3580, 2014 | 313 | 2014 |
Dynamics of breast-cancer relapse reveal late-recurring ER-positive genomic subgroups OM Rueda, SJ Sammut, JA Seoane, SF Chin, JL Caswell-Jin, M Callari, ... Nature 567 (7748), 399-404, 2019 | 309 | 2019 |
Copynumber: Efficient algorithms for single- and multi-track copy number segmentation G Nilsen, K Liestøl, P Van Loo, HK Moen Vollan, MB Eide, OM Rueda, ... BMC genomics 13, 1-16, 2012 | 302 | 2012 |
Expansion sequencing: Spatially precise in situ transcriptomics in intact biological systems S Alon, DR Goodwin, A Sinha, AT Wassie, F Chen, ER Daugharthy, ... Science 371 (6528), eaax2656, 2021 | 292 | 2021 |
Multi-omic machine learning predictor of breast cancer therapy response SJ Sammut, M Crispin-Ortuzar, SF Chin, E Provenzano, HA Bardwell, ... Nature 601 (7894), 623-629, 2022 | 279 | 2022 |
Genome-driven integrated classification of breast cancer validated in over 7,500 samples HR Ali, OM Rueda, SF Chin, C Curtis, MJ Dunning, SAJR Aparicio, ... Genome biology 15, 1-14, 2014 | 243 | 2014 |
Imaging mass cytometry and multiplatform genomics define the phenogenomic landscape of breast cancer HR Ali, HW Jackson, VRT Zanotelli, E Danenberg, JR Fischer, H Bardwell, ... Nature Cancer 1 (2), 163-175, 2020 | 242 | 2020 |
Master regulators of FGFR2 signalling and breast cancer risk MNC Fletcher, MAA Castro, X Wang, I De Santiago, M O’Reilly, SF Chin, ... Nature communications 4 (1), 2464, 2013 | 210 | 2013 |