The vaccine adjuvant monophosphoryl lipid A as a TRIF-biased agonist of TLR4 V Mata-Haro, C Cekic, M Martin, PM Chilton, CR Casella, TC Mitchell Science 316 (5831), 1628-1632, 2007 | 1036 | 2007 |
Purinergic regulation of the immune system C Cekic, J Linden Nature Reviews Immunology 16 (3), 177-192, 2016 | 778 | 2016 |
Patrolling monocytes control tumor metastasis to the lung RN Hanna, C Cekic, D Sag, R Tacke, GD Thomas, H Nowyhed, E Herrley, ... Science 350 (6263), 985-990, 2015 | 478 | 2015 |
Myeloid Expression of Adenosine A2A Receptor Suppresses T and NK Cell Responses in the Solid Tumor Microenvironment C Cekic, YJ Day, D Sag, J Linden Cancer research 74 (24), 7250-7259, 2014 | 297 | 2014 |
Adenosine A2B Receptor Blockade Slows Growth of Bladder and Breast Tumors C Cekic, D Sag, Y Li, D Theodorescu, RM Strieter, J Linden The Journal of Immunology, 2012 | 230 | 2012 |
Regulation of lymphocyte function by adenosine J Linden, C Cekic Arteriosclerosis, thrombosis, and vascular biology 32 (9), 2097-2103, 2012 | 180 | 2012 |
The cholesterol transporter ABCG1 links cholesterol homeostasis and tumour immunity D Sag, C Cekic, R Wu, J Linden, CC Hedrick Nature communications 6 (1), 6354, 2015 | 179 | 2015 |
Adenosine A2A Receptors Intrinsically Regulate CD8+ T Cells in the Tumor Microenvironment C Cekic, J Linden Cancer research 74 (24), 7239-7249, 2014 | 177 | 2014 |
Extracellular adenosine regulates naive T cell development and peripheral maintenance C Cekic, D Sag, YJ Day, J Linden Journal of Experimental Medicine 210 (12), 2693-2706, 2013 | 125 | 2013 |
Selective activation of the p38 MAPK pathway by synthetic monophosphoryl lipid A C Cekic, CR Casella, CA Eaves, A Matsuzawa, H Ichijo, TC Mitchell Journal of Biological Chemistry 284 (46), 31982-31991, 2009 | 116 | 2009 |
IFN-β production by TLR4-stimulated innate immune cells is negatively regulated by GSK3-β H Wang, CA Garcia, K Rehani, C Cekic, P Alard, DF Kinane, T Mitchell, ... The Journal of Immunology 181 (10), 6797-6802, 2008 | 95 | 2008 |
The Expression of Adenosine A2B Receptor on Antigen-Presenting Cells Suppresses CD8+ T-cell Responses and Promotes Tumor Growth S Chen, I Akdemir, J Fan, J Linden, B Zhang, C Cekic Cancer immunology research 8 (8), 1064-1074, 2020 | 53 | 2020 |
Reactivation of cAMP pathway by PDE4D inhibition represents a novel druggable axis for overcoming tamoxifen resistance in ER-positive breast cancer RR Mishra, N Belder, SA Ansari, M Kayhan, H Bal, U Raza, PG Ersan, ... Clinical Cancer Research 24 (8), 1987-2001, 2018 | 48 | 2018 |
MyD88-dependent SHIP1 regulates proinflammatory signaling pathways in dendritic cells after monophosphoryl lipid A stimulation of TLR4 C Cekic, CR Casella, D Sag, F Antignano, J Kolb, J Suttles, MR Hughes, ... The Journal of Immunology 186 (7), 3858-3865, 2011 | 47 | 2011 |
Adenosine receptor signaling targets both PKA and Epac pathways to polarize dendritic cells to a suppressive phenotype M Kayhan, A Koyas, I Akdemir, AC Savas, C Cekic The Journal of Immunology 203 (12), 3247-3255, 2019 | 31 | 2019 |
Targeting adenosine with adenosine deaminase 2 to inhibit growth of solid tumors L Wang, LM Londono, J Cowell, O Saatci, M Aras, PG Ersan, S Serra, ... Cancer Research 81 (12), 3319-3332, 2021 | 23 | 2021 |
Interleukin-7 protects CD8+ T cells from adenosine-mediated immunosuppression A Koyas, S Tucer, M Kayhan, AC Savas, I Akdemir, C Cekic Science Signaling 14 (674), eabb1269, 2021 | 16 | 2021 |
Ecto-5′-Nucleotidase (CD73) Regulates the Survival of CD8+ T Cells MV Rosemblatt, B Parra-Tello, P Briceño, E Rivas-Yáñez, S Tucer, ... Frontiers in Cell and Developmental Biology 9, 647058, 2021 | 8 | 2021 |
Modulation of myeloid cells by adenosine signaling C Cekic Current Opinion in Pharmacology 53, 134-145, 2020 | 5 | 2020 |
Methods and compositions for treating cancer TVK George A. Gaitanaris, Marc A. Gavin, Robert H. LEMUS, Caglar CEKIC ... WO Patent WO2023039578A1, 2023 | | 2023 |