First bispecific inhibitors of the epidermal growth factor receptor kinase and the NF-κB activity as novel anticancer agents MM Hamed, SS Darwish, J Herrmann, AH Abadi, M Engel Journal of medicinal chemistry 60 (7), 2853-2868, 2017 | 33 | 2017 |
Development of novel 2, 4-bispyridyl thiophene–based compounds as highly potent and selective Dyrk1A inhibitors. Part I: benzamide and benzylamide derivatives SS Darwish, M Abdel-Halim, M Salah, AH Abadi, W Becker, M Engel European Journal of Medicinal Chemistry 157, 1031-1050, 2018 | 23 | 2018 |
Development of novel amide–derivatized 2, 4-bispyridyl thiophenes as highly potent and selective Dyrk1A inhibitors. Part II: Identification of the cyclopropylamide moiety as a … SS Darwish, M Abdel-Halim, AK ElHady, M Salah, AH Abadi, W Becker, ... European Journal of Medicinal Chemistry 158, 270-285, 2018 | 20 | 2018 |
Pharmacological inhibition of protein kinase C (PKC) ζ downregulates the expression of cytokines involved in the pathogenesis of chronic obstructive pulmonary disease (COPD) M Abdel-Halim, SS Darwish, AK ElHady, J Hoppstädter, AH Abadi, ... European Journal of Pharmaceutical Sciences 93, 405-409, 2016 | 15 | 2016 |
Novel 6-hydroxybenzothiazol-2-carboxamides as potent and selective monoamine oxidase B inhibitors endowed with neuroprotective activity OM Al-Saad, M Gabr, SS Darwish, M Rullo, L Pisani, DV Miniero, ... European Journal of Medicinal Chemistry 269, 116266, 2024 | 3 | 2024 |
From EGFR kinase inhibitors to anti-inflammatory drugs: Optimization and biological evaluation of (4-(phenylamino) quinazolinyl)-phenylthiourea derivatives as novel NF-κB … RA Wagdy, PJ Chen, MM Hamed, SS Darwish, SH Chen, AH Abadi, ... Bioorganic Chemistry 127, 105977, 2022 | 2 | 2022 |
Development of (4-Phenylamino) quinazoline Alkylthiourea Derivatives as Novel NF-κB Inhibitors SS Darwish, PJ Chen, MM Hamed, RA Wagdy, SH Chen, AH Abadi, ... Pharmaceuticals 15 (7), 778, 2022 | 2 | 2022 |
Dual targeting of inflammation and β-cell dysfunction for therapy of diabetes mellitus F Mustafa, M Abdel-Halim, R Abdel-Moniem, S Aziz, SS Darwish, ... Journal of Drug Delivery Science and Technology 97, 105718, 2024 | | 2024 |
N-Benzylated 5-Hydroxybenzothiophene-2-carboxamides as Multi-Targeted Clk/Dyrk Inhibitors and Potential Anticancer Agents N Mostafa, PJ Chen, SS Darwish, YC Su, MH Shiao, GA Piazza, AH Abadi, ... Cancers 16 (11), 2033, 2024 | | 2024 |
Design and Synthesis and Biological Evaluation of Novel Dyrk1A/1B kinase Inhibitors. S Darwish German University in Cairo, 2018 | | 2018 |
Design and Synthesis of Novel Quinazoline Derivatives as Potential Dual EGFR/NF-κB Inhibitors German University in Cairo, 2014 | | 2014 |