Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects EM Jimenez-Mateos, T Engel, P Merino-Serrais, RC McKiernan, ... Nature medicine 18 (7), 1087-1094, 2012 | 510 | 2012 |
Alterations in cholesterol metabolism as a risk factor for developing Alzheimer’s disease: Potential novel targets for treatment R Loera-Valencia, J Goikolea, C Parrado-Fernandez, P Merino-Serrais, ... The Journal of steroid biochemistry and molecular biology 190, 104-114, 2019 | 199 | 2019 |
Widespread changes in dendritic spines in a model of Alzheimer's disease S Knafo, L Alonso-Nanclares, J Gonzalez-Soriano, P Merino-Serrais, ... Cerebral Cortex 19 (3), 586-592, 2009 | 154 | 2009 |
The influence of phospho-tau on dendritic spines of cortical pyramidal neurons in patients with Alzheimer’s disease P Merino-Serrais, R Benavides-Piccione, L Blazquez-Llorca, ... Brain 136 (6), 1913-1928, 2013 | 152 | 2013 |
Antagomirs targeting microRNA-134 increase hippocampal pyramidal neuron spine volume in vivo and protect against pilocarpine-induced status epilepticus EM Jimenez-Mateos, T Engel, P Merino-Serrais, I Fernaud-Espinosa, ... Brain Structure and Function 220, 2387-2399, 2015 | 118 | 2015 |
Tau hyperphosphorylation induces oligomeric insulin accumulation and insulin resistance in neurons P Rodriguez-Rodriguez, A Sandebring-Matton, P Merino-Serrais, ... Brain 140 (12), 3269-3285, 2017 | 98 | 2017 |
27-Hydroxycholesterol impairs neuronal glucose uptake through an IRAP/GLUT4 system dysregulation MAM Ismail, L Mateos, S Maioli, P Merino-Serrais, Z Ali, M Lodeiro, ... Journal of Experimental Medicine 214 (3), 699-717, 2017 | 77 | 2017 |
Morphological alterations to neurons of the amygdala and impaired fear conditioning in a transgenic mouse model of Alzheimer's disease S Knafo, C Venero, P Merino‐Serrais, I Fernaud‐Espinosa, ... The Journal of Pathology: A Journal of the Pathological Society of Great …, 2009 | 75 | 2009 |
Aggregation of the inflammatory S100A8 precedes Aβ plaque formation in transgenic APP mice: positive feedback for S100A8 and Aβ productions M Lodeiro, E Puerta, MAM Ismail, P Rodriguez-Rodriguez, A Rönnbäck, ... Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2017 | 74 | 2017 |
Alterations in brain leptin signalling in spite of unchanged CSF leptin levels in Alzheimer's disease S Maioli, M Lodeiro, P Merino‐Serrais, F Falahati, W Khan, E Puerta, ... Aging cell 14 (1), 122-129, 2015 | 71 | 2015 |
27-Hydroxycholesterol induces aberrant morphology and synaptic dysfunction in hippocampal neurons P Merino-Serrais, R Loera-Valencia, P Rodriguez-Rodriguez, ... Cerebral cortex 29 (1), 429-446, 2019 | 60 | 2019 |
Combination of apolipoprotein E4 and high carbohydrate diet reduces hippocampal BDNF and arc levels and impairs memory in young mice S Maioli, E Puerta, P Merino-Serrais, L Fusari, F Gil-Bea, R Rimondini, ... Journal of Alzheimer's Disease 32 (2), 341-355, 2012 | 58 | 2012 |
Facilitation of AMPA receptor synaptic delivery as a molecular mechanism for cognitive enhancement S Knafo, C Venero, C Sánchez-Puelles, I Pereda-Peréz, A Franco, ... PLoS biology 10 (2), e1001262, 2012 | 54 | 2012 |
Abnormal tau phosphorylation in the thorny excrescences of CA3 hippocampal neurons in patients with Alzheimer's disease L Blazquez-Llorca, V Garcia-Marin, P Merino-Serrais, J Ávila, J DeFelipe Journal of Alzheimer's Disease 26 (4), 683-698, 2011 | 53 | 2011 |
Synaptic changes in the dentate gyrus of APP/PS1 transgenic mice revealed by electron microscopy L Alonso-Nanclares, P Merino-Serrais, S Gonzalez, J DeFelipe Journal of Neuropathology & Experimental Neurology 72 (5), 386-395, 2013 | 52 | 2013 |
Layer‐specific alterations to CA1 dendritic spines in a mouse model of Alzheimer's disease P Merino‐Serrais, S Knafo, L Alonso‐Nanclares, I Fernaud‐Espinosa, ... Hippocampus 21 (10), 1037-1044, 2011 | 51 | 2011 |
A brain atlas of synapse protein lifetime across the mouse lifespan E Bulovaite, Z Qiu, M Kratschke, A Zgraj, DG Fricker, EJ Tuck, R Gokhale, ... Neuron 110 (24), 4057-4073. e8, 2022 | 36 | 2022 |
Lithium treatment reverses irradiation-induced changes in rodent neural progenitors and rescues cognition G Zanni, S Goto, AF Fragopoulou, G Gaudenzi, V Naidoo, E Di Martino, ... Molecular psychiatry 26 (1), 322-340, 2021 | 36 | 2021 |
Hypercholesterolemia and 27-hydroxycholesterol increase S100A8 and RAGE expression in the brain: a link between cholesterol, Alarmins, and neurodegeneration R Loera-Valencia, MAM Ismail, J Goikolea, M Lodeiro, L Mateos, ... Molecular neurobiology 58 (12), 6063-6076, 2021 | 24 | 2021 |
Dendritic spines are lost in clusters in Alzheimer’s disease M Mijalkov, G Volpe, I Fernaud-Espinosa, J DeFelipe, JB Pereira, ... Scientific Reports 11 (1), 12350, 2021 | 24 | 2021 |