Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients JC Holter, SE Pischke, E de Boer, A Lind, S Jenum, AR Holten, K Tonby, ... Proceedings of the National Academy of Sciences 117 (40), 25018-25025, 2020 | 330 | 2020 |
Properdin binding to complement activating surfaces depends on initial C3b deposition M Harboe, C Johnson, S Nymo, K Ekholt, C Schjalm, JK Lindstad, ... Proceedings of the National Academy of Sciences 114 (4), E534-E539, 2017 | 83 | 2017 |
Increased interleukin-6 and macrophage chemoattractant protein-1 are associated with respiratory failure in COVID-19 M Jøntvedt Jørgensen, JC Holter, EE Christensen, C Schjalm, K Tonby, ... Scientific reports 10 (1), 21697, 2020 | 79 | 2020 |
Complement activation is associated with poor outcome after out-of-hospital cardiac arrest V Chaban, ER Nakstad, H Stær-Jensen, C Schjalm, I Seljeflot, J Vaage, ... Resuscitation 166, 129-136, 2021 | 18 | 2021 |
A conformational change of complement C5 is required for thrombin-mediated cleavage, revealed by a novel ex vivo human whole blood model preserving full thrombin activity PH Nilsson, C Johnson, QH Quach, A Macpherson, O Durrant, ... The Journal of Immunology 207 (6), 1641-1651, 2021 | 17 | 2021 |
Increased local inflammatory response to MOC31PE immunotoxin after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy EB Thorgersen, J Asvall, IS Frøysnes, C Schjalm, SG Larsen, S Dueland, ... Annals of Surgical Oncology 28 (9), 5252-5262, 2021 | 15 | 2021 |
Rapid systemic surge of IL-33 after severe human trauma: a prospective observational study O Sundnes, W Ottestad, C Schjalm, P Lundbäck, L la Cour Poulsen, ... Molecular Medicine 27, 1-10, 2021 | 12 | 2021 |
Age-dependent development of liver fibrosis in Glmp gt/gt mice CK Nesset, XY Kong, M Damme, C Schjalm, N Roos, EM Løberg, ... Fibrogenesis & tissue repair 9, 1-13, 2016 | 11 | 2016 |
Combined inhibition of C5 and CD14 attenuates systemic inflammation in a piglet model of meconium aspiration syndrome AM Thomas, C Schjalm, PH Nilsson, PHH Lindenskov, R Rørtveit, ... Neonatology 113 (4), 322-330, 2018 | 10 | 2018 |
Ficolins do not alter host immune responses to lipopolysaccharide-induced inflammation in vivo N Genster, O Østrup, C Schjalm, T Eirik Mollnes, JB Cowland, P Garred Scientific Reports 7 (1), 3852, 2017 | 10 | 2017 |
Lack of the lysosomal membrane protein, GLMP, in mice results in metabolic dysregulation in liver XY Kong, ET Kase, A Herskedal, C Schjalm, M Damme, CK Nesset, ... PLoS One 10 (6), e0129402, 2015 | 10 | 2015 |
Rickettsia conorii is a potent complement activator in vivo and combined inhibition of complement and CD14 is required for attenuation of the cytokine response ex vivo K Otterdal, A Portillo, E Astrup, JK Ludviksen, C Schjalm, D Raoult, ... Clinical Microbiology and Infection 22 (8), 734. e1-734. e6, 2016 | 9 | 2016 |
Intracellular complement component 3 attenuated ischemia-reperfusion injury in the isolated buffer-perfused mouse heart and is associated with improved metabolic homeostasis MK Torp, T Ranheim, C Schjalm, M Hjorth, CM Heiestad, KT Dalen, ... Frontiers in Immunology 13, 870811, 2022 | 8 | 2022 |
Open chest and pericardium facilitate transpulmonary passage of venous air emboli BS Storm, PS Halvorsen, H Skulstad, K Dybwik, C Schjalm, ... Acta Anaesthesiologica Scandinavica 65 (5), 648-655, 2021 | 7 | 2021 |
Circulating cell-free DNA is elevated in community-acquired bacterial pneumonia and predicts short-term outcome WW Siljan, JC Holter, SH Nymo, C Schjalm, F Müller, PA Jenum, ... Journal of Infection 73 (4), 383-386, 2016 | 7 | 2016 |
The complement component C5 is not responsible for the alternative pathway activity in rabbit erythrocyte hemolytic assays during eculizumab treatment LP van den Heuvel, NCAJ van de Kar, C Duineveld, A Sarlea, ... Cellular & Molecular Immunology 17 (6), 653-655, 2020 | 6 | 2020 |
Complement activation in 22q11. 2 deletion syndrome D Grinde, T Øverland, K Lima, C Schjalm, TE Mollnes, TG Abrahamsen Journal of Clinical Immunology 40, 515-523, 2020 | 6 | 2020 |
Complement component C3 and the TLR co-receptor CD14 are not involved in angiotensin II induced cardiac remodelling N Shahini, C Schjalm, PH Nilsson, MF Holt, JDS Øgaard, E Lien, ... Biochemical and Biophysical Research Communications 523 (4), 867-873, 2020 | 6 | 2020 |
Vitamin C, hydrocortisone, and the combination thereof significantly inhibited two of nine inflammatory markers induced by Escherichia coli but not by staphylococcus aureus … PMC Medeiros, C Schjalm, D Christiansen, M Sokolova, SE Pischke, ... Shock 57 (1), 72-80, 2022 | 4 | 2022 |
High serum CXCL10 in Rickettsia conorii infection is endothelial cell mediated subsequent to whole blood activation K Otterdal, A Portillo, E Astrup, J Ludviksen, G Davì, S Holm, F Santilli, ... Cytokine 83, 269-274, 2016 | 4 | 2016 |