The shared frameshift mutation landscape of microsatellite-unstable cancers suggests immunoediting during tumor evolution A Ballhausen, MJ Przybilla, M Jendrusch, S Haupt, E Pfaffendorf, ... Nature Communications 11 (1), 4740, 2020 | 111 | 2020 |
Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium P Møller, T Seppälä, JG Dowty, S Haupt, M Dominguez-Valentin, L Sunde, ... Hereditary cancer in clinical practice 20 (1), 36, 2022 | 35 | 2022 |
Mortality by age, gene and gender in carriers of pathogenic mismatch repair gene variants receiving surveillance for early cancer diagnosis and treatment: a report from the … M Dominguez-Valentin, S Haupt, TT Seppälä, JR Sampson, L Sunde, ... EClinicalMedicine 58, 2023 | 33 | 2023 |
Age‐dependent performance of BRAF mutation testing in Lynch syndrome diagnostics H Bläker, S Haupt, M Morak, E Holinski‐Feder, A Arnold, D Horst, ... International Journal of Cancer, 0 | 23 | |
Opportunities and challenges in machine learning‐based newborn screening—A systematic literature review E Zaunseder, S Haupt, U Mütze, SF Garbade, S Kölker, V Heuveline JIMD reports 63 (3), 250-261, 2022 | 21 | 2022 |
Mathematical modeling of multiple pathways in colorectal carcinogenesis using dynamical systems with Kronecker structure S Haupt, A Zeilmann, A Ahadova, H Bläker, M von Knebel Doeberitz, ... PLOS Computational Biology 17 (5), e1008970, 2021 | 18 | 2021 |
Hiflow3–technical report on release 2.0 S Gawlok, P Gerstner, S Haupt, V Heuveline, J Kratzke, P Lösel, K Mang, ... Preprint Series of the Engineering Mathematics and Computing Lab, 2017 | 16 | 2017 |
Dominantly inherited micro-satellite instable cancer–the four Lynch syndromes-an EHTG, PLSD position statement P Møller, TT Seppälä, A Ahadova, EJ Crosbie, E Holinski-Feder, R Scott, ... Hereditary Cancer in Clinical Practice 21 (1), 19, 2023 | 13 | 2023 |
A “two-in-one hit” model of shortcut carcinogenesis in MLH1 lynch syndrome carriers A Ahadova, A Stenzinger, T Seppälä, R Hüneburg, M Kloor, H Bläker, ... Gastroenterology 165 (1), 267-270. e4, 2023 | 13 | 2023 |
Machine Learning Methods Improve Specificity in Newborn Screening for Isovaleric Aciduria E Zaunseder, U Mütze, SF Garbade, S Haupt, P Feyh, GF Hoffmann, ... Metabolites 13 (2), 304, 2023 | 11 | 2023 |
Is HLA type a possible cancer risk modifier in Lynch syndrome? A Ahadova, J Witt, S Haupt, R Gallon, R Hüneburg, J Nattermann, ... International Journal of Cancer 152 (10), 2024-2031, 2023 | 10 | 2023 |
The shared neoantigen landscape of MSI cancers reflects immunoediting during tumor evolution A Ballhausen, MJ Przybilla, M Jendrusch, S Haupt, E Pfaffendorf, ... BioRxiv, 691469, 2019 | 7 | 2019 |
A simple approach for detecting HLA‐A*02 alleles in archival formalin‐fixed paraffin‐embedded tissue samples and an application example for studying cancer … J Witt, S Haupt, A Ahadova, L Bohaumilitzky, V Fuchs, A Ballhausen, ... HLA 101 (1), 24-33, 2023 | 4 | 2023 |
A computational model for investigating the evolution of colonic crypts during Lynch syndrome carcinogenesis S Haupt, N Gleim, A Ahadova, H Bläker, M von Knebel Doeberitz, M Kloor, ... Computational and Systems Oncology 1 (2), e1020, 2021 | 4 | 2021 |
Incidences of colorectal adenomas and cancers under colonoscopy surveillance suggest an accelerated “Big Bang” pathway to CRC in three of the four Lynch syndromes P Møller, S Haupt, A Ahadova, M Kloor, JR Sampson, L Sunde, T Seppälä, ... Hereditary Cancer in Clinical Practice 22 (1), 6, 2024 | 3 | 2024 |
BRAF mutation testing of MSI CRCs in Lynch syndrome diagnostics: performance and efficiency according to patient’s age H Bläker, S Haupt, M Morak, E Holinski-Feder, A Arnold, D Horst, ... medRxiv, 19009274, 2019 | 1 | 2019 |
Deep Learning and Explainable Artificial Intelligence for Improving Specificity and Detecting Metabolic Patterns in Newborn Screening E Zaunseder, U Mütze, SF Garbade, S Haupt, S Kölker, V Heuveline 2023 IEEE Symposium Series on Computational Intelligence (SSCI), 1566-1571, 2023 | | 2023 |
Mortality by age, gene and gender in carriers of pathogenic mismatch repair gene variants receiving surveillance for early cancer diagnosis and treatment: A report from the … M Dominguez-Valentin, S Haupt, TT Seppälä, JR Sampson, L Sunde, ... DOI: https://doi. org/10.1016/j. eclinm, 101909, 2023 | | 2023 |
Mathematical modeling of Lynch syndrome carcinogenesis S Haupt | | 2023 |
Unraveling the black boxes in early cancer development using mathematical modeling at different scales S Haupt, A Zeilmann, N Gleim, A Ahadova, H Bläker, ... 2022 Virtual Joint Mathematics Meetings (JMM 2022), 2022 | | 2022 |