In vitro cytotoxicity and in vivo efficacy, pharmacokinetics, and metabolism of 10074-G5, a novel small-molecule inhibitor of c-Myc/Max dimerization DM Clausen, J Guo, RA Parise, JH Beumer, MJ Egorin, JS Lazo, ... Journal of Pharmacology and Experimental Therapeutics 335 (3), 715-727, 2010 | 140 | 2010 |
A cell-targeted photodynamic nanomedicine strategy for head and neck cancers A Master, A Malamas, R Solanki, DM Clausen, JL Eiseman, A Sen Gupta Molecular pharmaceutics 10 (5), 1988-1997, 2013 | 75 | 2013 |
Intracellular metalloprotease activity controls intraneuronal Aβ aggregation and limits secretion of Aβ via exosomes J Pacheco-Quinto, D Clausen, R Pérez-González, H Peng, A Meszaros, ... The FASEB Journal 33 (3), 3758, 2019 | 42 | 2019 |
In vitro cytotoxicity, pharmacokinetics, tissue distribution, and metabolism of small-molecule protein kinase D inhibitors, kb-NB142-70 and kb-NB165-09, in mice bearing human … J Guo, DM Clausen, JH Beumer, RA Parise, MJ Egorin, ... Cancer chemotherapy and pharmacology 71, 331-344, 2013 | 30 | 2013 |
Specificity and diagnostic utility of cerebrospinal fluid CXCL13 in lyme neuroborreliosis EA Eckman, DM Clausen, AR Herdt, J Pacheco-Quinto, JJ Halperin Clinical Infectious Diseases 72 (10), 1719-1726, 2021 | 25 | 2021 |
Plasma pharmacokinetics and oral bioavailability of the 3, 4, 5, 6-tetrahydrouridine (THU) prodrug, triacetyl-THU (taTHU), in mice JH Beumer, JL Eiseman, JA Gilbert, JL Holleran, AE Yellow-Duke, ... Cancer chemotherapy and pharmacology 67, 421-430, 2011 | 20 | 2011 |
Analysis of Disialyllacto-N-Tetraose (DSLNT) content in milk from mothers of preterm infants D Hassinger, DM Clausen, S Nitka, A Herdt, I Griffin Journal of Human Lactation 36 (2), 291-298, 2020 | 18 | 2020 |
Vascular endothelial growth factor associated dissimilar cerebrovascular phenotypes in two different mouse models of Alzheimer's Disease NM Tataryn, V Singh, JP Dyke, HE Berk-Rauch, DM Clausen, E Aronowitz, ... Neurobiology of aging 107, 96-108, 2021 | 14 | 2021 |
Osmolality of commonly used oral medications in the neonatal intensive care unit DD Shah, A Kuzmov, D Clausen, A Siu, CA Robinson, K Kimler, R Meyers, ... The Journal of Pediatric Pharmacology and Therapeutics 26 (2), 172-178, 2021 | 9 | 2021 |
Effects of the aldehyde dehydrogenase inhibitor disulfiram on the plasma pharmacokinetics, metabolism, and toxicity of benzaldehyde dimethane sulfonate (NSC281612, DMS612, BEN … RA Parise, JH Beumer, DM Clausen, LH Rigatti, JA Ziegler, M Gasparetto, ... Cancer chemotherapy and pharmacology 72, 1195-1204, 2013 | 7 | 2013 |
Nascent Aβ42 Fibrillization in Synaptic Endosomes Precedes Plaque Formation in a Mouse Model of Alzheimer's-like β-Amyloidosis EA Eckman, DM Clausen, S Solé-Domėnech, CW Lee, C Sinobas-Pereira, ... Journal of Neuroscience 43 (50), 8812-8824, 2023 | 3 | 2023 |
Association of circulating FGF-21 levels in the first week of life and postnatal growth in hospitalized preterm infants KE Joung, D Clausen, A Herdt, A Presti, R Snyder, C Peters, H Christou, ... Metabolism Open 5, 100030, 2020 | 3 | 2020 |
In vitro cytotoxicity and in vivo efficacy, pharmacokinetics, and metabolism of pyrazole-based small molecule inhibitors of MDM2/4–p53 interaction SM Christner, DM Clausen, JH Beumer, RA Parise, J Guo, Y Huang, ... Cancer chemotherapy and pharmacology 76, 287-299, 2015 | 3 | 2015 |
Metabolism Open KE Joung, D Clausen, A Herdt, A Presti, R Snyder, C Peters, H Christou, ... | | 2020 |
Pharmacological chaperone therapeutics for Krabbe disease CW Lee, A Manavalan, D Clausen Molecular Genetics and Metabolism 126 (2), S92, 2019 | | 2019 |
P1‐215: DISRUPTION OF INTRACELLULAR PROTEOLYSIS TRIGGERS THE OLIGOMERIZATION OF AN ENDOGENOUS POOL OF Aβ J Pacheco-Quinto, D Clausen, H Peng, E Eckman Alzheimer's & Dementia 14 (7S_Part_6), P361-P361, 2018 | | 2018 |
Cytotoxicity in vitro, pharmacokinetics and tissue distribution of Link-N3 and Link-F3, two bivalent small molecules inhibitors of c-Myc/Max interactions in C.B-17 … J Guo, DM Clausen, EV Prochownik, SJ Metallo, RA Parise, JH Beumer, ... Cancer Research 73 (8_Supplement), 1019-1019, 2013 | | 2013 |
Novel small molecule inhibitors of MDM2/4-p53 interaction, YH264 and its ethyl ester YH263: preclinical evaluation SM Christner, DM Clausen, JH Beumer, RA Parise, Y Huang, ... Cancer Research 72 (8_Supplement), 4726-4726, 2012 | | 2012 |
Modulation of DMS612 (BEN) pharmacokinetics and metabolism in mice by disulfiram, and aldehyde dehydrogenase inhibitor RA Parise, J Beumer, D Clausen, M Egorin, J Covey, J Eiseman Cancer Research 71 (8_Supplement), 5465-5465, 2011 | | 2011 |
Plasma pharmacokinetics and metabolism of benzaldehyde dimethane sulfonate (NSC281612, DMS612, BEN) in mice RA Parise, JL Eiseman, MJ Egorin, DM Clausen, JM Covey, JH Beumer Cancer Research 70 (8_Supplement), 3524-3524, 2010 | | 2010 |