Mediation of poly (ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor SW Yu, H Wang, MF Poitras, C Coombs, WJ Bowers, HJ Federoff, ... Science 297 (5579), 259-263, 2002 | 2305 | 2002 |
Expanded CUG repeats trigger aberrant splicing of ClC-1 chloride channel pre-mRNA and hyperexcitability of skeletal muscle in myotonic dystrophy A Mankodi, MP Takahashi, H Jiang, CL Beck, WJ Bowers, RT Moxley, ... Molecular cell 10 (1), 35-44, 2002 | 778 | 2002 |
Regulation of neuronal traits by a novel transcriptional complex N Ballas, E Battaglioli, F Atouf, ME Andres, J Chenoweth, ME Anderson, ... Neuron 31 (3), 353-365, 2001 | 510 | 2001 |
Inhibitors of leucine-rich repeat kinase-2 protect against models of Parkinson's disease BD Lee, JH Shin, J VanKampen, L Petrucelli, AB West, HS Ko, YI Lee, ... Nature medicine 16 (9), 998-1000, 2010 | 425 | 2010 |
Tumor necrosis factor-alpha and the roles it plays in homeostatic and degenerative processes within the central nervous system SL Montgomery, WJ Bowers Journal of neuroimmune pharmacology 7 (1), 42-59, 2012 | 423 | 2012 |
Apoptosis-inducing factor substitutes for caspase executioners in NMDA-triggered excitotoxic neuronal death H Wang, SW Yu, DW Koh, J Lew, C Coombs, W Bowers, HJ Federoff, ... Journal of Neuroscience 24 (48), 10963-10973, 2004 | 388 | 2004 |
Tumor necrosis factor-alpha mediated signaling in neuronal homeostasis and dysfunction KM Park, WJ Bowers Cellular signalling 22 (7), 977-983, 2010 | 358 | 2010 |
Early correlation of microglial activation with enhanced tumor necrosis factor-alpha and monocyte chemoattractant protein-1 expression specifically within the entorhinal cortex … MC Janelsins, MA Mastrangelo, S Oddo, FM LaFerla, HJ Federoff, ... Journal of neuroinflammation 2, 1-12, 2005 | 319 | 2005 |
Modulation of the neuronal glutamate transporter EAAT4 by two interacting proteins M Jackson, W Song, MY Liu, L Jin, M Dykes-Hoberg, CG Lin, WJ Bowers, ... Nature 410 (6824), 89-93, 2001 | 311 | 2001 |
Detailed immunohistochemical characterization of temporal and spatial progression of Alzheimer's disease-related pathologies in male triple-transgenic mice MA Mastrangelo, WJ Bowers BMC neuroscience 9, 1-31, 2008 | 289 | 2008 |
Triple‐transgenic Alzheimer's disease mice exhibit region‐specific abnormalities in brain myelination patterns prior to appearance of amyloid and tau pathology MK Desai, KL Sudol, MC Janelsins, MA Mastrangelo, ME Frazer, ... Glia 57 (1), 54-65, 2009 | 269 | 2009 |
Chronic neuron-specific tumor necrosis factor-alpha expression enhances the local inflammatory environment ultimately leading to neuronal death in 3xTg-AD mice MC Janelsins, MA Mastrangelo, KM Park, KL Sudol, WC Narrow, S Oddo, ... The American journal of pathology 173 (6), 1768-1782, 2008 | 260 | 2008 |
Early oligodendrocyte/myelin pathology in Alzheimer's disease mice constitutes a novel therapeutic target MK Desai, MA Mastrangelo, DA Ryan, KL Sudol, WC Narrow, WJ Bowers The American journal of pathology 177 (3), 1422-1435, 2010 | 233 | 2010 |
GTPase activity plays a key role in the pathobiology of LRRK2 Y Xiong, CE Coombes, A Kilaru, X Li, AD Gitler, WJ Bowers, VL Dawson, ... PLoS genetics 6 (4), e1000902, 2010 | 225 | 2010 |
Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo PM Rappold, M Cui, JC Grima, RZ Fan, KL de Mesy-Bentley, L Chen, ... Nature communications 5 (1), 5244, 2014 | 207 | 2014 |
Brn3b/Brn3c double knockout mice reveal an unsuspected role for Brn3c in retinal ganglion cell axon outgrowth SW Wang, X Mu, WJ Bowers, DS Kim, DJ Plas, MC Crair, HJ Federoff, ... Oxford University Press for The Company of Biologists Limited 129 (2), 467-477, 2002 | 171 | 2002 |
HSV ICP0 recruits USP7 to modulate TLR-mediated innate response S Daubeuf, D Singh, Y Tan, H Liu, HJ Federoff, WJ Bowers, K Tolba Blood, The Journal of the American Society of Hematology 113 (14), 3264-3275, 2009 | 167 | 2009 |
Regeneration of the MPTP-lesioned dopaminergic system after convection-enhanced delivery of AAV2-GDNF AP Kells, J Eberling, X Su, P Pivirotto, J Bringas, P Hadaczek, WC Narrow, ... Journal of Neuroscience 30 (28), 9567-9577, 2010 | 138 | 2010 |
Neurotrophin-3 transduction attenuates cisplatin spiral ganglion neuron ototoxicity in the cochlea WJ Bowers, X Chen, H Guo, DR Frisina, HJ Federoff, RD Frisina Molecular Therapy 6 (1), 12-18, 2002 | 135 | 2002 |
Ablation of TNF-RI/RII expression in Alzheimer's disease mice leads to an unexpected enhancement of pathology: implications for chronic pan-TNF-α suppressive therapeutic … SL Montgomery, MA Mastrangelo, D Habib, WC Narrow, SA Knowlden, ... The American journal of pathology 179 (4), 2053-2070, 2011 | 129 | 2011 |