| Pharmacokinetic aspects of retinal drug delivery EM Del Amo, AK Rimpelä, E Heikkinen, OK Kari, E Ramsay, T Lajunen, ... Progress in retinal and eye research 57, 134-185, 2017 | 584 | 2017 |
| Implications of melanin binding in ocular drug delivery AK Rimpelä, M Reinisalo, L Hellinen, E Grazhdankin, H Kidron, A Urtti, ... Advanced drug delivery reviews 126, 23-43, 2018 | 111 | 2018 |
| Drug distribution to retinal pigment epithelium: studies on melanin binding, cellular kinetics, and single photon emission computed tomography/computed tomography imaging AK Rimpela, M Schmitt, S Latonen, M Hagstrom, M Antopolsky, ... Molecular Pharmaceutics 13 (9), 2977-2986, 2016 | 43 | 2016 |
| Pharmacokinetic simulations of intravitreal biologicals: aspects of drug delivery to the posterior and anterior segments AK Rimpelä, I Kiiski, F Deng, H Kidron, A Urtti Pharmaceutics 11 (1), 9, 2018 | 40 | 2018 |
| Melanin targeting for intracellular drug delivery: Quantification of bound and free drug in retinal pigment epithelial cells AK Rimpelä, M Hagström, H Kidron, A Urtti Journal of Controlled Release 283, 261-268, 2018 | 37 | 2018 |
| Interpretation of ocular melanin drug binding assays. Alternatives to the model of multiple classes of independent sites JA Manzanares, AK Rimpela, A Urtti Molecular pharmaceutics 13 (4), 1251-1257, 2016 | 25 | 2016 |
| Microscale thermophoresis as a screening tool to predict melanin binding of drugs L Hellinen, S Bahrpeyma, AK Rimpelä, M Hagström, M Reinisalo, A Urtti Pharmaceutics 12 (6), 554, 2020 | 24 | 2020 |
| Binding of small molecule drugs to porcine vitreous humor AK Rimpelä, S Reunanen, M Hagström, H Kidron, A Urtti Molecular pharmaceutics 15 (6), 2174-2179, 2018 | 22 | 2018 |
| Characterization and validation of in vitro and in vivo models to investigate TNF-α-induced inflammation in retinal diseases CM Weigelt, N Zippel, H Fuchs, AK Rimpelä, T Schönberger, B Stierstorfer, ... Translational Vision Science & Technology 11 (5), 18-18, 2022 | 11 | 2022 |
| Quantification of drugs in distinctly separated ocular substructures of albino and pigmented rats AK Rimpelä, M Garneau, KS Baum-Kroker, T Schönberger, F Runge, ... Pharmaceutics 12 (12), 1174, 2020 | 10 | 2020 |
| Mechanistic model for the prediction of small-molecule vitreal clearance combining diffusion-limited and permeability-limited clearance AK Rimpela, Y Cui, A Sauer Molecular Pharmaceutics 18 (7), 2703-2713, 2021 | 7 | 2021 |
| Ocular melanin binding of drugs: in vitro binding studies S Bahrpeyma, AK Rimpelä, M Hagström, A Urtti Acta Ophthalmologica 97, 2019 | 3 | 2019 |
| Ocular melanin binding of drugs: in vitro binding studies combined to a pharmacokinetic model AK Rimpelä Master's thesis. Available on the Helda library of the University of Helsinki, 2014 | 2 | 2014 |
| Physiologically-based pharmacokinetic (PBPK) modelling of the rat eye: insights into ocular drug distribution after systemic administration AK Rimpelä, G Ma, M Freiwald, A Sauer Investigative Ophthalmology & Visual Science 65 (7), 3984-3984, 2024 | | 2024 |
| Predicting intravitreal clearance of small-molecule drugs using Caco-2 permeability as a surrogate for ocular tissue permeability AK Rimpelä, Y Cui, A Sauer Investigative Ophthalmology & Visual Science 62 (8), 1188-1188, 2021 | | 2021 |
| A novel method for isolating rat eye substructures for measuring drug concentrations in different ocular target tissues AK Rimpelä, M Garneau, K Baum-Kroker, A Sauer Investigative Ophthalmology & Visual Science 61 (7), 33-33, 2020 | | 2020 |
| Ocular Pharmacokinetic Effects of Drug Binding to Melanin Pigment and the Vitreous Humor AK Rimpelä Helsingin yliopisto, 2018 | | 2018 |
| Ocular pharmacokinetics and pharmacodynamics A Urtti, E Del Amo, L Pelkonen, AK Rimpelä, H Kidron, M Reinisalo Acta Ophthalmologica 95, 2017 | | 2017 |
| Importance of cellular factors in the retention of melanin‐binding drugs in pigmented ocular tissues AK Rimpelä, A Urtti Acta Ophthalmologica 95, 2017 | | 2017 |
| Supplementary Materials: Microscale Thermophoresis as a Screening Tool to Predict Melanin Binding of Drugs L Hellinen, S Bahrpeyma, AK Rimpelä, M Hagström, M Reinisalo, A Urtti | | |
Arto UrttiUniversity of Helsinki在 helsinki.fi 的电子邮件经过验证
Arto UrttiUniversity of Helsinki在 helsinki.fi 的电子邮件经过验证