关注
Robert E Ziegler
Robert E Ziegler
Senior Scientist, AstraZeneca
在 astrazeneca.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
7‐Step Flow Synthesis of the HIV Integrase Inhibitor Dolutegravir
RE Ziegler, BK Desai, JA Jee, BF Gupton, TD Roper, TF Jamison
Angewandte Chemie International Edition 54, 7181-7185, 2018
1002018
Thiourea-catalyzed enantioselective addition of indoles to pyrones: Alkaloid cores with quaternary carbons
CS Yeung, RE Ziegler, JA Porco Jr, EN Jacobsen
Journal of the American Chemical Society 136 (39), 13614-13617, 2014
792014
Development of an alkaloid-pyrone annulation: Synthesis of pleiomaltinine
RE Ziegler, SJ Tan, TS Kam, JA Porco Jr
Angewandte Chemie (International ed. in English) 51 (37), 9348, 2012
342012
Divergent Oxidative Couplings between Indoles and 2, 3-Dihydroxybenzoic Acid Derivatives for the Biomimetic Synthesis of Voacalgine A and Bipleiophylline
N Denizot, D Lachkar, C Kouklovsky, E Poupon, L Evanno, G Vincent
Synthesis 50 (21), 4229-4242, 2018
232018
Highly enantioselective Michael addition of dithiomalonates to nitroolefins catalyzed by new bifunctional chiral thioureas
JN Yuan, HX Liu, QQ Tian, N Ji, K Shen, W He
Synthesis 50 (13), 2577-2586, 2018
122018
AiZynth impact on medicinal chemistry practice at AstraZeneca
JD Shields, R Howells, G Lamont, Y Leilei, A Madin, CE Reimann, ...
RSC Medicinal Chemistry 15 (4), 1085-1095, 2024
82024
Multiomic profiling of breast cancer cells uncovers stress MAPK-associated sensitivity to AKT degradation
EC Erickson, I You, G Perry, A Dugourd, KA Donovan, C Crafter, ...
Science signaling 17 (825), eadf2670, 2024
32024
Development of an enantioselective alkaloid addition to pyrones and studies towards the synthesis of vinylallene natural products
RE Ziegler
Boston University, 2016
12016
Heteroaromatic compounds
SN Mlynarski, JW Johannes, AL Verano, XL Zheng, RE Ziegler, ...
US Patent App. 18/308,009, 2024
2024
Synthesis of Benzothiazinones from Benzoyl Thiocarbamates: Application to Clinical Candidates for Tuberculosis Treatment
W Connors, R DeKorte, SCC Lucas, A Gopalsamy, RE Ziegler
European Journal of Organic Chemistry 2022 (34), e202200684, 2022
2022
Flow synthesis of dolutegravir: Translating batch processes into flow
R Ziegler, B Desai, JA Jee, T Roper, T Jamison
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 2018
2018
Development of an enantioselective alkaloid addition to pyrones and studies towards the total synthesis of vinylallene natural products
R Ziegler
2016
Development of an Alkaloid—Pyrone Annulation: Synthesis of Pleiomaltinine (XIII).
RE Ziegler, SJ Tan, TS Kam, JAJ Porco
ChemInform 44 (8), no-no, 2013
2013
Supporting Information Thiourea-catalyzed Enantioselective Addition of Indoles to Pyrones: Alkaloid Cores with Quaternary Carbons
CS Yeung, RE Ziegler, JA Porco Jr, EN Jacobsen
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