7‐Step Flow Synthesis of the HIV Integrase Inhibitor Dolutegravir RE Ziegler, BK Desai, JA Jee, BF Gupton, TD Roper, TF Jamison Angewandte Chemie International Edition 54, 7181-7185, 2018 | 100 | 2018 |
Thiourea-catalyzed enantioselective addition of indoles to pyrones: Alkaloid cores with quaternary carbons CS Yeung, RE Ziegler, JA Porco Jr, EN Jacobsen Journal of the American Chemical Society 136 (39), 13614-13617, 2014 | 79 | 2014 |
Development of an alkaloid-pyrone annulation: Synthesis of pleiomaltinine RE Ziegler, SJ Tan, TS Kam, JA Porco Jr Angewandte Chemie (International ed. in English) 51 (37), 9348, 2012 | 34 | 2012 |
Divergent Oxidative Couplings between Indoles and 2, 3-Dihydroxybenzoic Acid Derivatives for the Biomimetic Synthesis of Voacalgine A and Bipleiophylline N Denizot, D Lachkar, C Kouklovsky, E Poupon, L Evanno, G Vincent Synthesis 50 (21), 4229-4242, 2018 | 23 | 2018 |
Highly enantioselective Michael addition of dithiomalonates to nitroolefins catalyzed by new bifunctional chiral thioureas JN Yuan, HX Liu, QQ Tian, N Ji, K Shen, W He Synthesis 50 (13), 2577-2586, 2018 | 12 | 2018 |
AiZynth impact on medicinal chemistry practice at AstraZeneca JD Shields, R Howells, G Lamont, Y Leilei, A Madin, CE Reimann, ... RSC Medicinal Chemistry 15 (4), 1085-1095, 2024 | 8 | 2024 |
Multiomic profiling of breast cancer cells uncovers stress MAPK-associated sensitivity to AKT degradation EC Erickson, I You, G Perry, A Dugourd, KA Donovan, C Crafter, ... Science signaling 17 (825), eadf2670, 2024 | 3 | 2024 |
Development of an enantioselective alkaloid addition to pyrones and studies towards the synthesis of vinylallene natural products RE Ziegler Boston University, 2016 | 1 | 2016 |
Heteroaromatic compounds SN Mlynarski, JW Johannes, AL Verano, XL Zheng, RE Ziegler, ... US Patent App. 18/308,009, 2024 | | 2024 |
Synthesis of Benzothiazinones from Benzoyl Thiocarbamates: Application to Clinical Candidates for Tuberculosis Treatment W Connors, R DeKorte, SCC Lucas, A Gopalsamy, RE Ziegler European Journal of Organic Chemistry 2022 (34), e202200684, 2022 | | 2022 |
Flow synthesis of dolutegravir: Translating batch processes into flow R Ziegler, B Desai, JA Jee, T Roper, T Jamison ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 2018 | | 2018 |
Development of an enantioselective alkaloid addition to pyrones and studies towards the total synthesis of vinylallene natural products R Ziegler | | 2016 |
Development of an Alkaloid—Pyrone Annulation: Synthesis of Pleiomaltinine (XIII). RE Ziegler, SJ Tan, TS Kam, JAJ Porco ChemInform 44 (8), no-no, 2013 | | 2013 |
Supporting Information Thiourea-catalyzed Enantioselective Addition of Indoles to Pyrones: Alkaloid Cores with Quaternary Carbons CS Yeung, RE Ziegler, JA Porco Jr, EN Jacobsen | | |