| FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation JJ Hu, X Liu, S Xia, Z Zhang, Y Zhang, J Zhao, J Ruan, X Luo, X Lou, ... Nature immunology 21 (7), 736-745, 2020 | 776 | 2020 |
| Single-cell transcriptome profiling reveals neutrophil heterogeneity in homeostasis and infection X Xie, Q Shi, P Wu, X Zhang, H Kambara, J Su, H Yu, SY Park, R Guo, ... Nature immunology 21 (9), 1119-1133, 2020 | 539 | 2020 |
| Gasdermin D exerts anti-inflammatory effects by promoting neutrophil death H Kambara, F Liu, X Zhang, P Liu, B Bajrami, Y Teng, L Zhao, S Zhou, ... Cell reports 22 (11), 2924-2936, 2018 | 387 | 2018 |
| Constitutive neutrophil apoptosis: mechanisms and regulation HR Luo, F Loison American journal of hematology 83 (4), 288-295, 2008 | 378 | 2008 |
| Small molecule-induced cytosolic activation of protein kinase Akt rescues ischemia-elicited neuronal death H Jo, S Mondal, D Tan, E Nagata, S Takizawa, AK Sharma, Q Hou, ... Proceedings of the National Academy of Sciences 109 (26), 10581-10586, 2012 | 346 | 2012 |
| Akt as a mediator of cell death HR Luo, H Hattori, MA Hossain, L Hester, Y Huang, W Lee-Kwon, ... Proceedings of the National Academy of Sciences 100 (20), 11712-11717, 2003 | 314 | 2003 |
| CVTree: a phylogenetic tree reconstruction tool based on whole genomes J Qi, H Luo, B Hao Nucleic acids research 32 (suppl_2), W45-W47, 2004 | 297 | 2004 |
| The voltage-gated proton channel Hv1 enhances brain damage from ischemic stroke LJ Wu, G Wu, MRA Sharif, A Baker, Y Jia, FH Fahey, HR Luo, EP Feener, ... Nature neuroscience 15 (4), 565-573, 2012 | 258 | 2012 |
| Novel mechanism of PTEN regulation by its phosphatidylinositol 4, 5-bisphosphate binding motif is critical for chemotaxis M Iijima, YE Huang, HR Luo, F Vazquez, PN Devreotes Journal of Biological Chemistry 279 (16), 16606-16613, 2004 | 258 | 2004 |
| Inositol pyrophosphates mediate chemotaxis in Dictyostelium via pleckstrin homology domain-PtdIns (3, 4, 5) P3 interactions HR Luo, YE Huang, JC Chen, A Saiardi, M Iijima, K Ye, Y Huang, ... Cell 114 (5), 559-572, 2003 | 235 | 2003 |
| A synthetic 7, 8-dihydroxyflavone derivative promotes neurogenesis and exhibits potent antidepressant effect X Liu, CB Chan, SW Jang, S Pradoldej, J Huang, K He, LH Phun, ... Journal of medicinal chemistry 53 (23), 8274-8286, 2010 | 232 | 2010 |
| Reactive oxygen species-induced actin glutathionylation controls actin dynamics in neutrophils J Sakai, J Li, KK Subramanian, S Mondal, B Bajrami, H Hattori, Y Jia, ... Immunity 37 (6), 1037-1049, 2012 | 215 | 2012 |
| Leukotriene B4-driven neutrophil recruitment to the skin is essential for allergic skin inflammation MK Oyoshi, R He, Y Li, S Mondal, J Yoon, R Afshar, M Chen, DM Lee, ... Immunity 37 (4), 747-758, 2012 | 212 | 2012 |
| S-nitrosylation of N-ethylmaleimide sensitive factor mediates surface expression of AMPA receptors Y Huang, HY Man, Y Sekine-Aizawa, Y Han, K Juluri, H Luo, J Cheah, ... Neuron 46 (4), 533-540, 2005 | 209 | 2005 |
| PIKE: a nuclear GTPase that enhances PI3kinase activity and is regulated by protein 4.1 N K Ye, KJ Hurt, FY Wu, M Fang, HR Luo, JJ Hong, S Blackshaw, CD Ferris, ... Cell 103 (6), 919-930, 2000 | 192 | 2000 |
| Phospholipase Cγ1 is a physiological guanine nucleotide exchange factor for the nuclear GTPase PIKE K Ye, B Aghdasi, HR Luo, JL Moriarity, FY Wu, JJ Hong, KJ Hurt, SS Bae, ... Nature 415 (6871), 541-544, 2002 | 191 | 2002 |
| Stem cell factor SALL4 represses the transcriptions of PTEN and SALL1 through an epigenetic repressor complex J Lu, H Jeong, N Kong, Y Yang, J Carroll, HR Luo, LE Silberstein, ... PloS one 4 (5), e5577, 2009 | 189 | 2009 |
| Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis H Hattori, KK Subramanian, J Sakai, Y Jia, Y Li, TF Porter, F Loison, ... Proceedings of the National Academy of Sciences 107 (8), 3546-3551, 2010 | 187 | 2010 |
| Identification and characterization of a novel inositol hexakisphosphate kinase A Saiardi, E Nagata, HR Luo, AM Snowman, SH Snyder Journal of Biological Chemistry 276 (42), 39179-39185, 2001 | 175 | 2001 |
| GSDMD is critical for autoinflammatory pathology in a mouse model of Familial Mediterranean Fever A Kanneganti, RKS Malireddi, PHV Saavedra, L Vande Walle, ... Journal of Experimental Medicine 215 (6), 1519-1529, 2018 | 170 | 2018 |
