Regulation of intercellular adhesion molecule‐1 (CD54) gene expression KA Roebuck, A Finnegan Journal of leukocyte biology 66 (6), 876-888, 1999 | 777 | 1999 |
Inhibition of protein tyrosine phosphorylation in T cells by a novel immunosuppressive agent, Leflunomide (∗) X Xu, JW Williams, EG Bremer, A Finnegan, ASF Chong Journal of Biological Chemistry 270 (21), 12398-12403, 1995 | 255 | 1995 |
Antigen-specific B cells are required as APCs and autoantibody-producing cells for induction of severe autoimmune arthritis SK O’Neill, MJ Shlomchik, TT Glant, Y Cao, PD Doodes, A Finnegan The Journal of Immunology 174 (6), 3781-3788, 2005 | 253 | 2005 |
Regulation of b cell function by the immunosuppressive agent Leflunomide1 KF Siemasko, ASF Chong, JW Williams, EG Bremer, A Finnegan Transplantation 61 (4), 635-642, 1996 | 249 | 1996 |
IFN-gamma and IL-2 are protective in the skin but pathologic in the corneas of HSV-1-infected mice. RL Hendricks, TM Tumpey, A Finnegan Journal of immunology (Baltimore, Md.: 1950) 149 (9), 3023-3028, 1992 | 232 | 1992 |
Leflunomide (HWA 486), a novel immunomodulating compound for the treatment of autoimmune disorders and reactions leading to transplantation rejection RR Bartlett, M Dimitrijevic, T Mattar, T Zielinski, T Germann, E Rüde, ... Agents and actions 32, 10-21, 1991 | 221 | 1991 |
The immunosuppressive metabolite of leflunomide, A77 1726, affects murine T cells through two biochemical mechanisms. RT Elder, X Xu, JW Williams, H Gong, A Finnegan, AS Chong Journal of immunology (Baltimore, Md.: 1950) 159 (1), 22-27, 1997 | 211 | 1997 |
Inhibition of JAK3 and STAT6 tyrosine phosphorylation by the immunosuppressive drug leflunomide leads to a block in IgG1 production K Siemasko, ASF Chong, HM Jäck, H Gong, JW Williams, A Finnegan The Journal of Immunology 160 (4), 1581-1588, 1998 | 209 | 1998 |
IL-27 induces a Th1 immune response and susceptibility to experimental arthritis Y Cao, PD Doodes, TT Glant, A Finnegan The Journal of Immunology 180 (2), 922-930, 2008 | 193 | 2008 |
Inhibition of the epidermal growth factor receptor tyrosine kinase activity by leflunomide T Mattar, K Kochhar, R Bartlett, EG Bremer, A Finnegan FEBS letters 334 (2), 161-164, 1993 | 185 | 1993 |
Th1 type lymphocyte reactivity to metals in patients with total hip arthroplasty NJ Hallab, M Caicedo, A Finnegan, JJ Jacobs Journal of orthopaedic surgery and research 3, 1-11, 2008 | 184 | 2008 |
Proteoglycan (aggrecan)-induced arthritis in BALB/c mice is a Th1-type disease regulated by Th2 cytokines A Finnegan, K Mikecz, P Tao, TT Glant The Journal of Immunology 163 (10), 5383-5390, 1999 | 183 | 1999 |
Two activities of the immunosuppressive metabolite of leflunomide, A77 1726: Inhibition of pyrimidine nucleotide synthesis and protein tyrosine phosphorylation X Xu, JW Williams, H Gong, A Finnegan, ASF Chong Biochemical pharmacology 52 (4), 527-534, 1996 | 180 | 1996 |
IL-4 and IL-12 regulate proteoglycan-induced arthritis through Stat-dependent mechanisms A Finnegan, MJ Grusby, CD Kaplan, SK O’Neill, H Eibel, T Koreny, ... The Journal of Immunology 169 (6), 3345-3352, 2002 | 179 | 2002 |
Cutting edge: regulation of T cell activation threshold by CD28 costimulation through targeting Cbl-b for ubiquitination J Zhang, T Bárdos, D Li, I Gál, C Vermes, J Xu, K Mikecz, A Finnegan, ... The Journal of Immunology 169 (5), 2236-2240, 2002 | 177 | 2002 |
Proteoglycan-induced arthritis: immune regulation, cellular mechanisms, and genetics TT Glant, A Finnegan, K Mikecz Critical Reviews™ in Immunology 23 (3), 2003 | 168 | 2003 |
Expression of CD80/86 on B cells is essential for autoreactive T cell activation and the development of arthritis SK O’Neill, Y Cao, KM Hamel, PD Doodes, G Hutas, A Finnegan The Journal of Immunology 179 (8), 5109-5116, 2007 | 160 | 2007 |
Cutting edge: Cbl-b: one of the key molecules tuning CD28-and CTLA-4-mediated T cell costimulation D Li, I Gál, C Vermes, ML Alegre, ASF Chong, L Chen, Q Shao, ... The Journal of Immunology 173 (12), 7135-7139, 2004 | 130 | 2004 |
Critical roles of glycosaminoglycan side chains of cartilage proteoglycan (aggrecan) in antigen recognition and presentation TT Glant, EI Buzás, A Finnegan, G Negroiu, G Cs-Szabó, K Mikecz The Journal of immunology 160 (8), 3812-3819, 1998 | 130 | 1998 |
Collagen-induced arthritis is exacerbated in IL-10-deficient mice A Finnegan, CD Kaplan, Y Cao, H Eibel, TT Glant, J Zhang Arthritis Res Ther 5, 1-7, 2002 | 128 | 2002 |