Fault diagnosis with multivariate statistical models part I: using steady state fault signatures S Yoon, JF MacGregor Journal of process control 11 (4), 387-400, 2001 | 442 | 2001 |
Statistical and causal model‐based approaches to fault detection and isolation S Yoon, JF MacGregor AIChE Journal 46 (9), 1813-1824, 2000 | 183 | 2000 |
N-glycosylation design and control of therapeutic monoclonal antibodies S Sha, C Agarabi, K Brorson, DY Lee, S Yoon Trends in biotechnology 34 (10), 835-846, 2016 | 159 | 2016 |
The current scientific and regulatory landscape in advancing integrated continuous biopharmaceutical manufacturing AC Fisher, MH Kamga, C Agarabi, K Brorson, SL Lee, S Yoon Trends in biotechnology 37 (3), 253-267, 2019 | 148 | 2019 |
Principal‐component analysis of multiscale data for process monitoring and fault diagnosis S Yoon, JF MacGregor AIChE Journal 50 (11), 2891-2903, 2004 | 128 | 2004 |
Kinetic modeling of mammalian cell culture bioprocessing: the quest to advance biomanufacturing S Kyriakopoulos, KS Ang, M Lakshmanan, Z Huang, S Yoon, R Gunawan, ... Biotechnology Journal 13 (3), 1700229, 2018 | 85 | 2018 |
In‐line monitoring of amino acids in mammalian cell cultures using raman spectroscopy and multivariate chemometrics models H Bhatia, H Mehdizadeh, D Drapeau, S Yoon Engineering in Life Sciences 18 (1), 55-61, 2018 | 81 | 2018 |
Consequences of trace metal variability and supplementation on Chinese hamster ovary (CHO) cell culture performance: A review of key mechanisms and considerations RJ Graham, H Bhatia, S Yoon Biotechnology and Bioengineering 116 (12), 3446-3456, 2019 | 77 | 2019 |
Distributed perfusion bioreactor system for continuous culture of biological cells O Berteau, Y Seongkyu, D Sergeant, T Poskin US Patent 10,214,718, 2019 | 75 | 2019 |
Optimization of critical quality attributes in continuous twin-screw wet granulation via design space validated with pilot scale experimental data H Liu, SC Galbraith, B Ricart, C Stanton, B Smith-Goettler, L Verdi, ... International Journal of Pharmaceutics 525 (1), 249-263, 2017 | 67 | 2017 |
Cellular and metabolic engineering of oleaginous yeast Yarrowia lipolytica for bioconversion of hydrophobic substrates into high‐value products YHV Soong, N Liu, S Yoon, C Lawton, D Xie Engineering in Life Sciences 19 (6), 423-443, 2019 | 47 | 2019 |
MicroRNA-146a inhibits epithelial mesenchymal transition in non-small cell lung cancer by targeting insulin receptor substrate 2 DH Park, HS Jeon, SY Lee, YY Choi, HW Lee, S Yoon, JC Lee, YS Yoon, ... International journal of oncology 47 (4), 1545-1553, 2015 | 47 | 2015 |
Mechanistic modeling and applications for CHO cell culture development and production S Sha, Z Huang, Z Wang, S Yoon Current opinion in chemical engineering 22, 54-61, 2018 | 46 | 2018 |
Quantitative intracellular flux modeling and applications in biotherapeutic development and production using CHO cell cultures Z Huang, DY Lee, S Yoon Biotechnology and bioengineering 114 (12), 2717-2728, 2017 | 44 | 2017 |
Estimation of raw material performance in mammalian cell culture using near infrared spectra combined with chemometrics approaches HW Lee, A Christie, JJ Liu, S Yoon Biotechnology progress 28 (3), 824-832, 2012 | 43 | 2012 |
Impact of media and antifoam selection on monoclonal antibody production and quality using a high throughput micro‐bioreactor system SR Velugula‐Yellela, A Williams, N Trunfio, CJ Hsu, B Chavez, S Yoon, ... Biotechnology Progress 34 (1), 262-270, 2018 | 42 | 2018 |
Media formulation optimization: current and future opportunities SC Galbraith, H Bhatia, H Liu, S Yoon Current opinion in chemical engineering 22, 42-47, 2018 | 40 | 2018 |
Quantification of protein mixture in chromatographic separation using multi‐wavelength UV spectra MH Kamga, H Woo Lee, J Liu, S Yoon Biotechnology Progress 29 (3), 664-671, 2013 | 39 | 2013 |
Data fusion‐based assessment of raw materials in mammalian cell culture HW Lee, A Christie, J Xu, S Yoon Biotechnology and bioengineering 109 (11), 2819-2828, 2012 | 39 | 2012 |
An RNA-seq based transcriptomic investigation into the productivity and growth variants with Chinese hamster ovary cells S Sha, H Bhatia, S Yoon Journal of biotechnology 271, 37-46, 2018 | 37 | 2018 |