| Mice devoid of PrP are resistant to scrapie H Büeler, A Aguzzi, A Sailer, RA Greiner, P Autenried, M Aguet, ... Cell 73 (7), 1339-1347, 1993 | 2683 | 1993 |
| Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein H Büeler, M Fischer, Y Lang, H Bluethmann, HP Lipp, SJ DeArmond, ... Nature 356 (6370), 577-582, 1992 | 2163 | 1992 |
| A model for gene therapy of human hereditary lymphedema MJ Karkkainen, A Saaristo, L Jussila, KA Karila, EC Lawrence, K Pajusola, ... Proceedings of the National Academy of Sciences 98 (22), 12677-12682, 2001 | 728 | 2001 |
| No propagation of prions in mice devoid of PrP A Sailer Cell 77 (7), 967-968, 1994 | 405 | 1994 |
| Impaired mitochondrial dynamics and function in the pathogenesis of Parkinson's disease H Büeler Experimental neurology 218 (2), 235-246, 2009 | 398 | 2009 |
| High Prion and PrPSc Levels but Delayed Onset of Disease in Scrapie-Inoculated Mice Heterozygous for a Disrupted PrP Gene H Büeler, A Raeber, A Sailer, M Fischer, A Aguzzi, C Weissmann Molecular Medicine 1, 19-30, 1994 | 340 | 1994 |
| Metabolic stress modulates Alzheimer’s β-secretase gene transcription via SIRT1-PPARγ-PGC-1 in neurons R Wang, JJ Li, S Diao, YD Kwak, L Liu, L Zhi, H Büeler, NR Bhat, ... Cell metabolism 17 (5), 685-694, 2013 | 221 | 2013 |
| Influence of promoter and WHV post-transcriptional regulatory element on AAV-mediated transgene expression in the rat brain JC Paterna, T Moccetti, A Mura, J Feldon, H Büeler Gene therapy 7 (15), 1304-1311, 2000 | 221 | 2000 |
| Comparative analysis of genetically modified dendritic cells and tumor cells as therapeutic cancer vaccines C Klein, H Bueler, RC Mulligan The Journal of experimental medicine 191 (10), 1699, 2000 | 218 | 2000 |
| Adenoviral VEGF‐C overexpression induces blood vessel enlargement, tortuosity, and leakiness but no sprouting angiogenesis in the skin or mucous membranes A Saaristo, T Veikkola, B Enholm, M Hytönen, J Arola, K Pajusola, ... The FASEB journal 16 (9), 1041-1049, 2002 | 215 | 2002 |
| Lymphangiogenic gene therapy with minimal blood vascular side effects A Saaristo, T Veikkola, T Tammela, B Enholm, MJ Karkkainen, K Pajusola, ... The Journal of experimental medicine 196 (6), 719, 2002 | 208 | 2002 |
| Increased mitochondrial calcium sensitivity and abnormal expression of innate immunity genes precede dopaminergic defects in Pink1-deficient mice RS Akundi, Z Huang, J Eason, JD Pandya, L Zhi, WA Cass, PG Sullivan, ... PloS one 6 (1), e16038, 2011 | 207 | 2011 |
| Increased motoneuron survival and improved neuromuscular function in transgenic ALS mice after intraspinal injection of an adeno-associated virus encoding Bcl-2 M Azzouz, A Hottinger, JC Paterna, AD Zurn, P Aebischer, H Büeler Human molecular genetics 9 (5), 803-811, 2000 | 180 | 2000 |
| Hsp70 gene transfer by adeno-associated virus inhibits MPTP-induced nigrostriatal degeneration in the mouse model of Parkinson disease Z Dong, DP Wolfer, HP Lipp, H Büeler Molecular therapy 11 (1), 80-88, 2005 | 172 | 2005 |
| DJ-1 and Parkin modulate dopamine-dependent behavior and inhibit MPTP-induced nigral dopamine neuron loss in mice JC Paterna, A Leng, E Weber, J Feldon, H Büeler Molecular Therapy 15 (4), 698-704, 2007 | 167 | 2007 |
| Gene transfer into neurons from hippocampal slices: comparison of recombinant Semliki Forest Virus, adenovirus, adeno-associated virus, lentivirus, and measles virus MU Ehrengruber, S Hennou, H Büeler, HY Naim, N Déglon, K Lundstrom Molecular and Cellular Neuroscience 17 (5), 855-871, 2001 | 161 | 2001 |
| Cell-type-specific characteristics modulate the transduction efficiency of adeno-associated virus type 2 and restrain infection of endothelial cells K Pajusola, M Gruchala, H Joch, TF Lüscher, S Ylä-Herttuala, ... Journal of virology 76 (22), 11530-11540, 2002 | 158 | 2002 |
| Recombinant AAV vectors containing the foot and mouth disease virus 2A sequence confer efficient bicistronic gene expression in cultured cells and rat substantia nigra neurons S Furler, JC Paterna, M Weibel, H Büeler Gene therapy 8 (11), 864-873, 2001 | 158 | 2001 |
| Adenoviral and adeno-associated viral transfer of genes to the peripheral nervous system M Glatzel, E Flechsig, B Navarro, MA Klein, JC Paterna, H Büeler, ... Proceedings of the National Academy of Sciences 97 (1), 442-447, 2000 | 154 | 2000 |
| Dopamine-dependent neurodegeneration in rats induced by viral vector-mediated overexpression of the parkin target protein, CDCrel-1 Z Dong, B Ferger, JC Paterna, D Vogel, S Furler, M Osinde, J Feldon, ... Proceedings of the National Academy of Sciences 100 (21), 12438-12443, 2003 | 152 | 2003 |
Michel AguetEcole Polytechnique Fédérale de Lausanne (EPFL)在 epfl.ch 的电子邮件经过验证
