Targeting the nucleolus as a therapeutic strategy in human disease A Corman, O Sirozh, V Lafarga, O Fernandez-Capetillo Trends in Biochemical Sciences 48 (3), 274-287, 2023 | 28 | 2023 |
Widespread displacement of DNA‐and RNA‐binding factors underlies toxicity of arginine‐rich cell‐penetrating peptides V Lafarga, O Sirozh, I Díaz‐López, A Galarreta, M Hisaoka, E Zarzuela, ... The EMBO Journal 40 (13), e103311, 2021 | 25 | 2021 |
Activation of the integrated stress response is a vulnerability for multidrug‐resistant FBXW7‐deficient cells L Sanchez‐Burgos, B Navarro‐González, S García‐Martín, O Sirozh, ... EMBO Molecular Medicine 14 (9), e15855, 2022 | 17 | 2022 |
Nucleolar stress caused by arginine-rich peptides triggers a ribosomopathy and accelerates aging in mice O Sirozh, A Saez-Mas, B Jung, L Sanchez-Burgos, E Zarzuela, ... Molecular Cell 84 (8), 1527-1540. e7, 2024 | 3 | 2024 |
Generalized displacement of DNA-and RNA-binding factors mediates the toxicity of arginine-rich cell-penetrating peptides V Lafarga, O Sirozh, I Diaz-Lopez, M Hisaoka, E Zarzuela, J Boskovic, ... Biorxiv, 441808, 2018 | 3 | 2018 |
Basic concepts and emergent disease mechanisms of amyotrophic lateral sclerosis O Sirozh, A Saez-Mas, V Lafarga, O Fernandez-Capetillo Academic Press, 2023 | 2 | 2023 |
New regulators of the tetracycline‐inducible gene expression system identified by chemical and genetic screens V Colicchia, M Häggblad, O Sirozh, B Porebski, M Balan, X Li, ... FEBS Open bio 12 (10), 1896-1908, 2022 | 2 | 2022 |
Hnrnpk Overexpression Drives Nucleolar Aberrancies Causing Ribosomopathies P Aguilar-Garrido, M Velasco-Estevez, MÁ Navarro-Aguadero, ... Blood 142, 5659, 2023 | | 2023 |
S179: HNRNPK OVEREXPRESSION DRIVES NUCLEOLAR ABERRANCIES CAUSING RIBOSOMPATHIES PA Garrido, MV Estevez, MÁN Aguadero, MH Sánchez, P Malaney, ... HemaSphere 7, e8819188, 2023 | | 2023 |
The nucleolar aberrancies that drive ribosome impairment induced by RNA binding proteins are hallmarks of aging P Aguilar-Garrido, M Velasco-Estévez, MÁ Navarro-Aguadero, ... bioRxiv, 2023.03. 07.531270, 2023 | | 2023 |
Chemical and genetic screens identify new regulators of tetracycline-inducible gene expression system in mammalian cells V Colicchia, M Häggblad, O Sirozh, B Porebski, M Balan, L Lidemalm, ... bioRxiv, 2022.03. 16.484587, 2022 | | 2022 |