| Striking antibody evasion manifested by the Omicron variant of SARS-CoV-2 L Liu, S Iketani, Y Guo, JFW Chan, M Wang, L Liu, Y Luo, H Chu, Y Huang, ... Nature 602 (7898), 676-681, 2022 | 1177 | 2022 |
| Comparative tropism, replication kinetics, and cell damage profiling of SARS-CoV-2 and SARS-CoV with implications for clinical manifestations, transmissibility, and laboratory … H Chu, JFW Chan, TTT Yuen, H Shuai, S Yuan, Y Wang, B Hu, CCY Yip, ... The Lancet Microbe 1 (1), e14-e23, 2020 | 862 | 2020 |
| Antibody evasion properties of SARS-CoV-2 Omicron sublineages S Iketani, L Liu, Y Guo, L Liu, JFW Chan, Y Huang, M Wang, Y Luo, J Yu, ... Nature 604 (7906), 553-556, 2022 | 773 | 2022 |
| Comparative replication and immune activation profiles of SARS-CoV-2 and SARS-CoV in human lungs: an ex vivo study with implications for the pathogenesis of COVID-19 H Chu, JFW Chan, Y Wang, TTT Yuen, Y Chai, Y Hou, H Shuai, D Yang, ... Clinical Infectious Diseases 71 (6), 1400-1409, 2020 | 737 | 2020 |
| Attenuated replication and pathogenicity of SARS-CoV-2 B. 1.1. 529 Omicron H Shuai, JFW Chan, B Hu, Y Chai, TTT Yuen, F Yin, X Huang, C Yoon, ... Nature 603 (7902), 693-699, 2022 | 530 | 2022 |
| Attenuated interferon and proinflammatory response in SARS-CoV-2–infected human dendritic cells is associated with viral antagonism of STAT1 phosphorylation D Yang, H Chu, Y Hou, Y Chai, H Shuai, ACY Lee, X Zhang, Y Wang, ... The Journal of infectious diseases 222 (5), 734-745, 2020 | 195 | 2020 |
| Pathogenicity, transmissibility, and fitness of SARS-CoV-2 Omicron in Syrian hamsters S Yuan, ZW Ye, R Liang, K Tang, AJ Zhang, G Lu, CP Ong, VK Man Poon, ... Science 377 (6604), 428-433, 2022 | 137 | 2022 |
| Host and viral determinants for efficient SARS-CoV-2 infection of the human lung H Chu, B Hu, X Huang, Y Chai, D Zhou, Y Wang, H Shuai, D Yang, Y Hou, ... Nature communications 12 (1), 134, 2021 | 131 | 2021 |
| Emerging SARS-CoV-2 variants expand species tropism to murines H Shuai, JFW Chan, TTT Yuen, C Yoon, JC Hu, L Wen, B Hu, D Yang, ... EBioMedicine 73, 2021 | 124 | 2021 |
| An orally available Mpro inhibitor is effective against wild-type SARS-CoV-2 and variants including Omicron BX Quan, H Shuai, AJ Xia, Y Hou, R Zeng, XL Liu, GF Lin, JX Qiao, WP Li, ... Nature Microbiology 7 (5), 716-725, 2022 | 75 | 2022 |
| Spike mutations contributing to the altered entry preference of SARS-CoV-2 omicron BA. 1 and BA. 2 B Hu, JFW Chan, H Liu, Y Liu, Y Chai, J Shi, H Shuai, Y Hou, X Huang, ... Emerging Microbes & Infections 11 (1), 2275-2287, 2022 | 58 | 2022 |
| Coronaviruses exploit a host cysteine-aspartic protease for replication H Chu, Y Hou, D Yang, L Wen, H Shuai, C Yoon, J Shi, Y Chai, TTT Yuen, ... Nature 609 (7928), 785-792, 2022 | 48 | 2022 |
| SARS-CoV-2 induces a more robust innate immune response and replicates less efficiently than SARS-CoV in the human intestines: an ex vivo study with implications on … H Chu, JFW Chan, Y Wang, TTT Yuen, Y Chai, H Shuai, D Yang, B Hu, ... Cellular and molecular gastroenterology and hepatology 11 (3), 771-781, 2021 | 48 | 2021 |
| Berbamine inhibits SARS-CoV-2 infection by compromising TRPMLs-mediated endolysosomal trafficking of ACE2 L Huang, TTT Yuen, Z Ye, S Liu, G Zhang, H Chu, J Yue Signal Transduction and Targeted Therapy 6 (1), 168, 2021 | 38 | 2021 |
| Bacillus Calmette-Guérin–induced trained immunity protects against SARS-CoV-2 challenge in K18-hACE2 mice BZ Zhang, H Shuai, HR Gong, JC Hu, B Yan, TTT Yuen, YF Hu, C Yoon, ... JCI insight 7 (11), 2022 | 34 | 2022 |
| SARS-CoV-2 infection induces inflammatory bone loss in golden Syrian hamsters W Qiao, HE Lau, H Xie, VKM Poon, CCS Chan, H Chu, S Yuan, TTT Yuen, ... Nature communications 13 (1), 2539, 2022 | 34 | 2022 |
| Virological features and pathogenicity of SARS-CoV-2 Omicron BA. 2 JFW Chan, B Hu, Y Chai, H Shuai, H Liu, J Shi, Y Liu, C Yoon, J Zhang, ... Cell Reports Medicine 3 (9), 2022 | 27 | 2022 |
| A molecularly engineered, broad-spectrum anti-coronavirus lectin inhibits SARS-CoV-2 and MERS-CoV infection in vivo JFW Chan, YJ Oh, S Yuan, H Chu, ML Yeung, D Canena, CCS Chan, ... Cell Reports Medicine 3 (10), 2022 | 26 | 2022 |
| The SARS-CoV-2 Omicron (B. 1.1. 529) variant exhibits altered pathogenicity, transmissibility, and fitness in the golden Syrian hamster model S Yuan, ZW Ye, R Liang, K Tang, AJ Zhang, G Lu, CP Ong, VKM Poon, ... BioRxiv, 2022.01. 12.476031, 2022 | 22 | 2022 |
| Targeting SUMO modification of the non-structural protein 5 of Zika virus as a host-targeting antiviral strategy Z Zhu, H Chu, L Wen, S Yuan, KKH Chik, TTT Yuen, CCY Yip, D Wang, ... International journal of molecular sciences 20 (2), 392, 2019 | 21 | 2019 |
