The development of RAPTA compounds for the treatment of tumors BS Murray, MV Babak, CG Hartinger, PJ Dyson Coordination Chemistry Reviews 306, 86-114, 2016 | 460 | 2016 |
Development of anticancer agents: wizardry with osmium M Hanif, MV Babak, CG Hartinger Drug Discovery Today 19 (10), 1640-1648, 2014 | 183 | 2014 |
Target profiling of an antimetastatic RAPTA agent by chemical proteomics: relevance to the mode of action MV Babak, SM Meier, KVM Huber, J Reynisson, AA Legin, MA Jakupec, ... Chemical science 6 (4), 2449-2456, 2015 | 155 | 2015 |
Modulation of intracellular copper levels as the mechanism of action of anticancer copper complexes: Clinical relevance MV Babak, D Ahn Biomedicines 9 (8), 852, 2021 | 122 | 2021 |
Copper (II) thiosemicarbazone complexes induce marked ROS accumulation and promote nrf2-mediated antioxidant response in highly resistant breast cancer cells A Sîrbu, O Palamarciuc, MV Babak, JM Lim, K Ohui, EA Enyedy, S Shova, ... Dalton Transactions 46 (12), 3833-3847, 2017 | 105 | 2017 |
New water-soluble copper (II) complexes with morpholine–thiosemicarbazone hybrids: Insights into the anticancer and antibacterial mode of action K Ohui, E Afanasenko, F Bacher, RLX Ting, A Zafar, N Blanco-Cabra, ... Journal of medicinal chemistry 62 (2), 512-530, 2018 | 104 | 2018 |
PlatinER: A highly potent anticancer platinum (II) complex that induces endoplasmic reticulum stress driven immunogenic cell death MJR Tham, MV Babak, WH Ang Angewandte Chemie International Edition 59 (43), 19070-19078, 2020 | 85 | 2020 |
Dual‐targeting dual‐action platinum (IV) platform for enhanced anticancer activity and reduced nephrotoxicity MV Babak, Y Zhi, B Czarny, TB Toh, L Hooi, EKH Chow, WH Ang, ... Angewandte Chemie International Edition 58 (24), 8109-8114, 2019 | 85 | 2019 |
Half‐Sandwich Ruthenium (II) Biotin Conjugates as Biological Vectors to Cancer Cells MV Babak, D Plażuk, SM Meier, HJ Arabshahi, J Reynisson, B Rychlik, ... Chemistry–A European Journal 21 (13), 5110-5117, 2015 | 76 | 2015 |
From Catalysis to Cancer: Toward Structure–Activity Relationships for Benzimidazol-2-ylidene-Derived N-Heterocyclic-Carbene Complexes as Anticancer Agents NYS Lam, D Truong, H Burmeister, MV Babak, HU Holtkamp, ... Inorganic chemistry 57 (22), 14427-14434, 2018 | 68 | 2018 |
Structural determinants of p53-independence in anticancer ruthenium-arene schiff-base complexes MJ Chow, MV Babak, DYQ Wong, G Pastorin, C Gaiddon, WH Ang Molecular Pharmaceutics 13 (7), 2543-2554, 2016 | 58 | 2016 |
PIPAC-OX: a phase I study of oxaliplatin-based pressurized intraperitoneal aerosol chemotherapy in patients with peritoneal metastases G Kim, HL Tan, R Sundar, B Lieske, CE Chee, J Ho, A Shabbir, MV Babak, ... Clinical Cancer Research 27 (7), 1875-1881, 2021 | 56 | 2021 |
Rollover cyclometalated bipyridine platinum complexes as potent anticancer agents: impact of the ancillary ligands on the mode of action MV Babak, M Pfaffeneder-Kmen, SM Meier-Menches, MS Legina, ... Inorganic chemistry 57 (5), 2851-2864, 2018 | 56 | 2018 |
Interfering with Metabolic Profile of Triple‐Negative Breast Cancers Using Rationally Designed Metformin Prodrugs MV Babak, KR Chong, P Rapta, M Zannikou, HM Tang, L Reichert, ... Angewandte Chemie International Edition 60 (24), 13405-13413, 2021 | 43 | 2021 |
NO Releasing and Anticancer Properties of Octahedral Ruthenium–Nitrosyl Complexes with Equatorial 1H-Indazole Ligands E Orlowska, MV Babak, O Domotor, EA Enyedy, P Rapta, M Zalibera, ... Inorganic Chemistry 57 (17), 10702-10717, 2018 | 42 | 2018 |
Development of an efficient dual‐action GST‐inhibiting anticancer platinum (IV) prodrug KGZ Lee, MV Babak, A Weiss, PJ Dyson, P Nowak‐Sliwinska, ... ChemMedChem 13 (12), 1210-1217, 2018 | 42 | 2018 |
RutheniumII(η6-arene) Complexes of Thiourea Derivatives: Synthesis, Characterization and Urease Inhibition M Hanif, MAH Nawaz, MV Babak, J Iqbal, A Roller, BK Keppler, ... Molecules 19 (6), 8080-8092, 2014 | 41 | 2014 |
Am (m) ines make the difference: organoruthenium am (m) ine complexes and their chemistry in anticancer drug development MV Babak, SM Meier, AA Legin, MS Adib Razavi, A Roller, MA Jakupec, ... Chemistry–A European Journal 19 (13), 4308-4318, 2013 | 41 | 2013 |
Induction of the endoplasmic reticulum stress pathway by highly cytotoxic organoruthenium Schiff-base complexes MJ Chow, MV Babak, KW Tan, MC Cheong, G Pastorin, C Gaiddon, ... Molecular pharmaceutics 15 (8), 3020-3031, 2018 | 33 | 2018 |
Heteroleptic Pd (II) and Pt (II) Complexes with Redox-Active Ligands: Synthesis, Structure, and Multimodal Anticancer Mechanism NF Romashev, PA Abramov, IV Bakaev, IS Fomenko, DG Samsonenko, ... Inorganic Chemistry 61 (4), 2105-2118, 2022 | 32 | 2022 |