Multiscaled exploration of coupled folding and binding of an intrinsically disordered molecular recognition element in measles virus nucleoprotein Y Wang, X Chu, S Longhi, P Roche, W Han, E Wang, J Wang Proceedings of the National Academy of Sciences 110 (40), E3743-E3752, 2013 | 115 | 2013 |
Structure of a functional amyloid protein subunit computed using sequence variation P Tian, W Boomsma, Y Wang, DE Otzen, MH Jensen, K Lindorff-Larsen Journal of the American Chemical Society 137 (1), 22-25, 2015 | 107 | 2015 |
Structural basis of membrane protein chaperoning through the mitochondrial intermembrane space K Weinhäupl, C Lindau, A Hessel, Y Wang, C Schütze, T Jores, ... Cell 175 (5), 1365-1379. e25, 2018 | 101 | 2018 |
Importance of electrostatic interactions in the association of intrinsically disordered histone chaperone Chz1 and histone H2A. Z-H2B X Chu, Y Wang, L Gan, Y Bai, W Han, E Wang, J Wang PLoS computational biology 8 (7), e1002608, 2012 | 88 | 2012 |
Combining molecular dynamics simulations with small-angle X-ray and neutron scattering data to study multi-domain proteins in solution AH Larsen, Y Wang, S Bottaro, S Grudinin, L Arleth, K Lindorff-Larsen PLoS computational biology 16 (4), e1007870, 2020 | 85 | 2020 |
Multi-scaled explorations of binding-induced folding of intrinsically disordered protein inhibitor IA3 to its target enzyme J Wang, Y Wang, X Chu, SJ Hagen, W Han, E Wang PLoS computational biology 7 (4), e1001118, 2011 | 82 | 2011 |
Exploring the dynamic functional landscape of adenylate kinase modulated by substrates Y Wang, L Gan, E Wang, J Wang Journal of chemical theory and computation 9 (1), 84-95, 2013 | 76 | 2013 |
Mapping transiently formed and sparsely populated conformations on a complex energy landscape Y Wang, E Papaleo, K Lindorff-Larsen eLife 5 (2050-084X), e17505, 2016 | 68 | 2016 |
Frequency adaptive metadynamics for the calculation of rare-event kinetics Y Wang, O Valsson, P Tiwary, M Parrinello, K Lindorff-Larsen J Chem Phys 149 (7), 072309, 2018 | 66 | 2018 |
Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System DV Pedersen, TA Gadeberg, C Thomas, Y Wang, N Joram, RK Jensen, ... Frontiers in Immunology, 2019 | 58 | 2019 |
Dynamic conformational change regulates the protein-DNA recognition: an investigation on binding of a Y-family polymerase to its target DNA X Chu, F Liu, BA Maxwell, Y Wang, Z Suo, H Wang, W Han, J Wang PLoS computational biology 10 (9), e1003804, 2014 | 55 | 2014 |
Exploration of multi-state conformational dynamics and underlying global functional landscape of maltose binding protein Y Wang, C Tang, E Wang, J Wang PLoS computational biology 8 (4), e1002471, 2012 | 55 | 2012 |
Biomolecular Conformational Changes and Ligand Binding: From Kinetics to Thermodynamics Y Wang, J Martins, K Lindorff-Larsen Chemical Science, 2017 | 53 | 2017 |
Substrate-induced conformational dynamics of the dopamine transporter AK Nielsen, IR Möller, Y Wang, SGF Rasmussen, K Lindorff-Larsen, ... Nature Communications 10 (1), 2714, 2019 | 51 | 2019 |
DEER-PREdict: Software for Efficient Calculation of Spin-Labeling EPR and NMR Data from Conformational Ensembles G Tesei, JM Martins, MBA Kunze, Y Wang, R Crehuet, K Lindorff-Larsen PLoS computational biology, 2021 | 43 | 2021 |
PolyUbiquitin chain linkage topology selects the functions from the underlying binding landscape Y Wang, C Tang, E Wang, J Wang PLoS computational biology 10 (7), e1003691, 2014 | 43 | 2014 |
Multidomain protein solves the folding problem by multifunnel combined landscape: Theoretical investigation of a Y-family DNA polymerase Y Wang, X Chu, Z Suo, E Wang, J Wang Journal of the American Chemical Society 134 (33), 13755-13764, 2012 | 43 | 2012 |
O-GlcNAcylation promotes pancreatic tumor growth by regulating malate dehydrogenase 1 Q Zhu, H Zhou, L Wu, Z Lai, D Geng, W Yang, J Zhang, Z Fan, W Qin, ... Nature Chemical Biology, 1-28, 2022 | 39 | 2022 |
Role of protein dynamics in transmembrane receptor signalling Y Wang, K Bugge, BB Kragelund, K Lindorff-Larsen Current Opinion in Structural Biology 48, 74-82, 2018 | 32 | 2018 |
Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding K Wang, R Dagil, T Lavstsen, S Misra, C Spliid, Y Wang, T Gustavsson, ... Nature Communications 12, 2956, 2021 | 29 | 2021 |