An hPer2 Phosphorylation Site Mutation in Familial Advanced Sleep Phase Syndrome KL Toh, CR Jones, Y He, EJ Eide, WA Hinz, DM Virshup, LJ Ptácek, ... Science 291 (5506), 1040-1043, 2001 | 1844 | 2001 |
Post-translational modifications regulate the ticking of the circadian clock M Gallego, DM Virshup Nature reviews Molecular cell biology 8 (2), 139-148, 2007 | 1013 | 2007 |
From promiscuity to precision: protein phosphatases get a makeover DM Virshup, S Shenolikar Molecular cell 33 (5), 537-545, 2009 | 744 | 2009 |
Control of mammalian circadian rhythm by CKIε-regulated proteasome-mediated PER2 degradation EJ Eide, MF Woolf, H Kang, P Woolf, W Hurst, F Camacho, EL Vielhaber, ... Molecular and cellular biology 25 (7), 2795-2807, 2005 | 627 | 2005 |
Regulation of β-catenin signaling by the B56 subunit of protein phosphatase 2A JM Seeling, JR Miller, R Gil, RT Moon, R White, DM Virshup Science 283 (5410), 2089-2091, 1999 | 593 | 1999 |
The B56 family of protein phosphatase 2A (PP2A) regulatory subunits encodes differentiation-induced phosphoproteins that target PP2A to both nucleus and cytoplasm B McCright, AM Rivers, S Audlin, DM Virshup Journal of Biological Chemistry 271 (36), 22081-22089, 1996 | 495 | 1996 |
Setting clock speed in mammals: the CK1ɛ tau mutation in mice accelerates circadian pacemakers by selectively destabilizing PERIOD proteins QJ Meng, L Logunova, ES Maywood, M Gallego, J Lebiecki, TM Brown, ... Neuron 58 (1), 78-88, 2008 | 444 | 2008 |
Nuclear entry of the circadian regulator mPER1 is controlled by mammalian casein kinase I ɛ E Vielhaber, E Eide, A Rivers, ZH Gao, DM Virshup Molecular and cellular biology 20 (13), 4888-4899, 2000 | 442 | 2000 |
The circadian regulatory proteins BMAL1 and cryptochromes are substrates of casein kinase Iε EJ Eide, EL Vielhaber, WA Hinz, DM Virshup Journal of Biological Chemistry 277 (19), 17248-17254, 2002 | 429 | 2002 |
Protein phosphatase 2A: a panoply of enzymes DM Virshup Current opinion in cell biology 12 (2), 180-185, 2000 | 426 | 2000 |
Pharmacological inhibition of the Wnt acyltransferase PORCN prevents growth of WNT-driven mammary cancer KD Proffitt, B Madan, Z Ke, V Pendharkar, L Ding, MA Lee, RN Hannoush, ... Cancer research 73 (2), 502-507, 2013 | 399 | 2013 |
Stroma provides an intestinal stem cell niche in the absence of epithelial Wnts Z Kabiri, G Greicius, B Madan, S Biechele, Z Zhong, H Zaribafzadeh, ... Development 141 (11), 2206-2215, 2014 | 352 | 2014 |
Wnt addiction of genetically defined cancers reversed by PORCN inhibition B Madan, Z Ke, N Harmston, SY Ho, AO Frois, J Alam, DA Jeyaraj, ... Oncogene 35 (17), 2197-2207, 2016 | 328 | 2016 |
Identification of cellular proteins required for simian virus 40 DNA replication MS Wold, DH Weinberg, DM Virshup, JJ Li, TJ Kelly Journal of Biological Chemistry 264 (5), 2801-2809, 1989 | 312 | 1989 |
Casein kinase I phosphorylates and destabilizes the β-catenin degradation complex ZH Gao, JM Seeling, V Hill, A Yochum, DM Virshup Proceedings of the National Academy of Sciences 99 (3), 1182-1187, 2002 | 309 | 2002 |
Identification of a new family of protein phosphatase 2A regulatory subunits (∗) B McCright, DM Virshup Journal of Biological Chemistry 270 (44), 26123-26128, 1995 | 305 | 1995 |
PDGFRα+ pericryptal stromal cells are the critical source of Wnts and RSPO3 for murine intestinal stem cells in vivo G Greicius, Z Kabiri, K Sigmundsson, C Liang, R Bunte, MK Singh, ... Proceedings of the National Academy of Sciences 115 (14), E3173-E3181, 2018 | 284 | 2018 |
Casein kinase 1: Complexity in the family JK Cheong, DM Virshup The international journal of biochemistry & cell biology 43 (4), 465-469, 2011 | 276 | 2011 |
A conserved docking motif for CK1 binding controls the nuclear localization of NFAT1 H Okamura, C Garcia-Rodriguez, H Martinson, J Qin, DM Virshup, A Rao Molecular and cellular biology 24 (10), 4184-4195, 2004 | 266 | 2004 |
Role for the PP2A/B56δ phosphatase in regulating 14-3-3 release from Cdc25 to control mitosis SS Margolis, JA Perry, CM Forester, LK Nutt, Y Guo, MJ Jardim, ... Cell 127 (4), 759-773, 2006 | 259 | 2006 |