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Jason Paul Lynch, PhD
Jason Paul Lynch, PhD
Postdoctoral Fellow, Massachusetts General Hospital and Harvard Medical School
在 mgh.harvard.edu 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
The receptor for complement component C3a mediates protection from intestinal ischemia-reperfusion injuries by inhibiting neutrophil mobilization
MCL Wu, FH Brennan, JPL Lynch, S Mantovani, S Phipps, RA Wetsel, ...
Proceedings of the National Academy of Sciences 110 (23), 9439-9444, 2013
1702013
Respiratory syncytial virus infection promotes necroptosis and HMGB1 release by airway epithelial cells
J Simpson, Z Loh, MA Ullah, JP Lynch, RB Werder, N Collinson, V Zhang, ...
American journal of respiratory and critical care medicine 201 (11), 1358-1371, 2020
1062020
Aeroallergen-induced IL-33 predisposes to respiratory virus–induced asthma by dampening antiviral immunity
JP Lynch, RB Werder, J Simpson, Z Loh, V Zhang, A Haque, K Spann, ...
Journal of Allergy and Clinical Immunology 138 (5), 1326-1337, 2016
922016
Toll-like receptor 7 gene deficiency and early-life Pneumovirus infection interact to predispose toward the development of asthma-like pathology in mice
GE Kaiko, Z Loh, K Spann, JP Lynch, A Lalwani, Z Zheng, S Davidson, ...
Journal of allergy and clinical immunology 131 (5), 1331-1339. e10, 2013
822013
Plasmacytoid dendritic cells protect from viral bronchiolitis and asthma through semaphorin 4a–mediated T reg expansion
JP Lynch, RB Werder, Z Loh, MAA Sikder, B Curren, V Zhang, MJ Rogers, ...
The Journal of experimental medicine 215 (2), 537, 2018
762018
Chronic IL-33 expression predisposes to virus-induced asthma exacerbations by increasing type 2 inflammation and dampening antiviral immunity
RB Werder, V Zhang, JP Lynch, N Snape, JW Upham, K Spann, S Phipps
Journal of Allergy and Clinical Immunology 141 (5), 1607-1619. e9, 2018
722018
The plasmacytoid dendritic cell: at the cross-roads in asthma
JP Lynch, SB Mazzone, MJ Rogers, JJ Arikkatt, Z Loh, AL Pritchard, ...
European Respiratory Journal 43 (1), 264-275, 2014
702014
Emerging strategies for engineering Escherichia coli Nissle 1917-based therapeutics
JP Lynch, L Goers, CF Lesser
Trends in pharmacological sciences 43 (9), 772-786, 2022
672022
PGD2/DP2 receptor activation promotes severe viral bronchiolitis by suppressing IFN-λ production
RB Werder, JP Lynch, JC Simpson, V Zhang, NH Hodge, M Poh, ...
Science translational medicine 10 (440), eaao0052, 2018
592018
The influence of the microbiome on early-life severe viral lower respiratory infections and asthma—food for thought?
JP Lynch, MAA Sikder, BF Curren, RB Werder, J Simpson, PÓ Cuív, ...
Frontiers in immunology 8, 156, 2017
462017
Regulatory T cells prevent inducible BALT formation by dampening neutrophilic inflammation
SY Foo, V Zhang, A Lalwani, JP Lynch, A Zhuang, CE Lam, PS Foster, ...
The Journal of Immunology 194 (9), 4567-4576, 2015
452015
Maternal diet modulates the infant microbiome and intestinal Flt3L necessary for dendritic cell development and immunity to respiratory infection
MAA Sikder, RB Rashid, T Ahmed, I Sebina, DR Howard, MA Ullah, ...
Immunity 56 (5), 1098-1114. e10, 2023
442023
Targeting the P2Y13 Receptor Suppresses IL-33 and HMGB1 Release and Ameliorates Experimental Asthma
RB Werder, MA Ullah, MM Rahman, J Simpson, JP Lynch, N Collinson, ...
American Journal of Respiratory and Critical Care Medicine 205 (3), 300-312, 2022
412022
HMGB1 amplifies ILC2-induced type-2 inflammation and airway smooth muscle remodelling
Z Loh, J Simpson, A Ullah, V Zhang, WJ Gan, JP Lynch, RB Werder, ...
PLoS pathogens 16 (7), e1008651, 2020
392020
Immunomodulation of Airway Epithelium Cell Activation by Mesenchymal Stromal Cells Ameliorates House Dust Mite–Induced Airway Inflammation in Mice
KM Duong, J Arikkatt, MA Ullah, JP Lynch, V Zhang, K Atkinson, PD Sly, ...
American journal of respiratory cell and molecular biology 53 (5), 615-624, 2015
352015
Engineered Escherichia coli for the in situ secretion of therapeutic nanobodies in the gut
JP Lynch, C González-Prieto, AZ Reeves, S Bae, U Powale, NP Godbole, ...
Cell host & microbe 31 (4), 634-649. e8, 2023
292023
IRF-3, IRF-7, and IPS-1 promote host defense against acute human metapneumovirus infection in neonatal mice
KM Spann, Z Loh, JP Lynch, A Ullah, V Zhang, E Baturcam, RB Werder, ...
The American journal of pathology 184 (6), 1795-1806, 2014
262014
Critical role of plasmacytoid dendritic cells in regulating gene expression and innate immune responses to human rhinovirus-16
Y Xi, NM Troy, D Anderson, OM Pena, JP Lynch, S Phipps, A Bosco, ...
Frontiers in Immunology 8, 1351, 2017
182017
Th2/Th17 reciprocal regulation: twists and turns in the complexity of asthma phenotypes
JP Lynch, MA Ferreira, S Phipps
Annals of Translational Medicine 4 (Suppl 1), 2016
182016
The absence of Interferon-β promotor stimulator-1 (IPS-1) predisposes to bronchiolitis and asthma-like pathology in response to pneumoviral infection in mice
J Simpson, JP Lynch, Z Loh, V Zhang, RB Werder, K Spann, S Phipps
Scientific Reports 7 (1), 2353, 2017
162017
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