Problems, challenges and promises: perspectives on precision medicine DJ Duffy Briefings in bioinformatics 17 (3), 494-504, 2016 | 145 | 2016 |
Integrative genome-scale analysis identifies epigenetic mechanisms of transcriptional deregulation in unfavorable neuroblastomas KO Henrich, S Bender, M Saadati, D Dreidax, M Gartlgruber, C Shao, ... Cancer research 76 (18), 5523-5537, 2016 | 111 | 2016 |
Wnt signaling promotes oral but suppresses aboral structures in Hydractinia metamorphosis and regeneration DJ Duffy, G Plickert, T Kuenzel, W Tilmann, U Frank Development 137 (18), 3057-3066, 2010 | 98 | 2010 |
GSK3 Inhibitors Regulate MYCN mRNA Levels and Reduce Neuroblastoma Cell Viability through Multiple Mechanisms, Including p53 and Wnt Signaling DJ Duffy, A Krstic, T Schwarzl, DG Higgins, W Kolch Molecular cancer therapeutics 13 (2), 454-467, 2014 | 91 | 2014 |
Induced stem cell neoplasia in a cnidarian by ectopic expression of a POU domain transcription factor RC Millane, J Kanska, DJ Duffy, C Seoighe, S Cunningham, G Plickert, ... Development 138 (12), 2429-2439, 2011 | 89 | 2011 |
Sea turtle fibropapilloma tumors share genomic drivers and therapeutic vulnerabilities with human cancers DJ Duffy, C Schnitzler, L Karpinski, R Thomas, J Whilde, C Eastman, ... Communications biology 1 (1), 63, 2018 | 49 | 2018 |
Plastic ingestion in post-hatchling sea turtles: assessing a major threat in Florida near shore waters CB Eastman, JA Farrell, L Whitmore, DR Rollinson Ramia, RS Thomas, ... Frontiers in Marine Science 7, 693, 2020 | 46 | 2020 |
A brain-derived neurotrophic factor mimetic is sufficient to restore cone photoreceptor visual function in an inherited blindness model C Daly, L Shine, T Heffernan, S Deeti, AL Reynolds, JJ O’Connor, ... Scientific reports 7 (1), 11320, 2017 | 43 | 2017 |
Retinoic acid and TGF-β signalling cooperate to overcome MYCN-induced retinoid resistance DJ Duffy, A Krstic, M Halasz, T Schwarzl, A Konietzny, K Iljin, DG Higgins, ... Genome medicine 9, 1-22, 2017 | 42 | 2017 |
Precision wildlife medicine: applications of the human‐centred precision medicine revolution to species conservation J Whilde, MQ Martindale, DJ Duffy Global Change Biology 23 (5), 1792-1805, 2017 | 42 | 2017 |
The promise and pitfalls of environmental DNA and RNA approaches for the monitoring of human and animal pathogens from aquatic sources JA Farrell, L Whitmore, DJ Duffy Bioscience 71 (6), 609-625, 2021 | 39 | 2021 |
Integrative omics reveals MYCN as a global suppressor of cellular signalling and enables network-based therapeutic target discovery in neuroblastoma DJ Duffy, A Krstic, M Halasz, T Schwarzl, D Fey, K Iljin, JP Mehta, K Killick, ... Oncotarget 6 (41), 43182, 2015 | 36 | 2015 |
Wnt signalling is a bi-directional vulnerability of cancer cells DJ Duffy, A Krstic, T Schwarzl, M Halasz, K Iljin, D Fey, B Haley, J Whilde, ... Oncotarget 7 (37), 60310, 2016 | 32 | 2016 |
A heat shock protein and Wnt signaling crosstalk during axial patterning and stem cell proliferation DJ Duffy, RC Millane, U Frank Developmental biology 362 (2), 271-281, 2012 | 32 | 2012 |
Molecular characterization of a marine turtle tumor epizootic, profiling external, internal and postsurgical regrowth tumors K Yetsko, JA Farrell, NB Blackburn, L Whitmore, MR Stammnitz, J Whilde, ... Communications biology 4 (1), 152, 2021 | 30 | 2021 |
Advances in dynamic modeling of colorectal cancer signaling-network regions, a path toward targeted therapies L Tortolina, DJ Duffy, M Maffei, N Castagnino, AM Carmody, W Kolch, ... Oncotarget 6 (7), 5041, 2015 | 29 | 2015 |
p19-INK4d inhibits neuroblastoma cell growth, induces differentiation and is hypermethylated and downregulated in MYCN-amplified neuroblastomas D Dreidax, S Bannert, KO Henrich, C Schröder, S Bender, CC Oakes, ... Human molecular genetics 23 (25), 6826-6837, 2014 | 29 | 2014 |
Detection and population genomics of sea turtle species via noninvasive environmental DNA analysis of nesting beach sand tracks and oceanic water JA Farrell, L Whitmore, N Mashkour, DR Rollinson Ramia, RS Thomas, ... Molecular Ecology Resources 22 (7), 2471-2493, 2022 | 24 | 2022 |
Inadvertent human genomic bycatch and intentional capture raise beneficial applications and ethical concerns with environmental DNA L Whitmore, M McCauley, JA Farrell, MR Stammnitz, SA Koda, ... Nature Ecology & Evolution 7 (6), 873-888, 2023 | 22 | 2023 |
Environmental DNA monitoring of oncogenic viral shedding and genomic profiling of sea turtle fibropapillomatosis reveals unusual viral dynamics JA Farrell, K Yetsko, L Whitmore, J Whilde, CB Eastman, DR Ramia, ... Communications biology 4 (1), 565, 2021 | 22 | 2021 |