| A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation CK Kaufman, C Mosimann, ZP Fan, S Yang, AJ Thomas, J Ablain, JL Tan, ... Science 351 (6272), aad2197, 2016 | 387 | 2016 |
| Genetic analysis of von Hippel‐Lindau disease M Nordstrom‐O'Brien, RB van der Luijt, E van Rooijen, ... Human mutation 31 (5), 521-537, 2010 | 357 | 2010 |
| Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma Y Yu, K Schleich, B Yue, S Ji, P Lohneis, K Kemper, MS Silvis, N Qutob, ... Cancer Cell, 2018 | 151 | 2018 |
| Zebrafish mutants in the von Hippel-Lindau tumor suppressor display a hypoxic response and recapitulate key aspects of Chuvash polycythemia E van Rooijen, EE Voest, I Logister, J Korving, T Schwerte, ... Blood, The Journal of the American Society of Hematology 113 (25), 6449-6460, 2009 | 148 | 2009 |
| A quantitative system for studying metastasis using transparent zebrafish S Heilmann, K Ratnakumar, EM Langdon, ER Kansler, IS Kim, ... Cancer research 75 (20), 4272-4282, 2015 | 136 | 2015 |
| von Hippel-Lindau tumor suppressor mutants faithfully model pathological hypoxia-driven angiogenesis and vascular retinopathies in zebrafish E van Rooijen, EE Voest, I Logister, J Bussmann, J Korving, FJ van Eeden, ... Disease models & mechanisms 3 (5-6), 343-353, 2010 | 119 | 2010 |
| LRRC50, a conserved ciliary protein implicated in polycystic kidney disease E van Rooijen, RH Giles, EE Voest, C van Rooijen, S Schulte-Merker, ... Journal of the American Society of Nephrology 19 (6), 1128-1138, 2008 | 99 | 2008 |
| A zebrafish model to study and therapeutically manipulate hypoxia signaling in tumorigenesis K Santhakumar, EC Judson, PM Elks, S McKee, S Elworthy, ... Cancer research 72 (16), 4017-4027, 2012 | 96 | 2012 |
| The Zebrafish Mutants dre, uki, and lep Encode Negative Regulators of the Hedgehog Signaling Pathway MJ Koudijs, MJ Den Broeder, A Keijser, E Wienholds, S Houwing, ... PLoS genetics 1 (2), e19, 2005 | 90 | 2005 |
| EXTL3 mutations cause skeletal dysplasia, immune deficiency, and developmental delay S Volpi, Y Yamazaki, PM Brauer, E van Rooijen, A Hayashida, ... Journal of Experimental Medicine, 2017 | 83 | 2017 |
| Stress from nucleotide depletion activates the transcriptional regulator HEXIM1 to suppress melanoma JL Tan, RD Fogley, RA Flynn, J Ablain, S Yang, V Saint-André, ZP Fan, ... Molecular cell 62 (1), 34-46, 2016 | 80 | 2016 |
| Cross-species analysis of enhancer logic using deep learning L Minnoye, II Taskiran, D Mauduit, M Fazio, L Van Aerschot, ... Genome research 30 (12), 1815-1834, 2020 | 77 | 2020 |
| The serine-threonine kinase LKB1 is essential for survival under energetic stress in zebrafish YU van der Velden, L Wang, J Zevenhoven, E van Rooijen, ... Proceedings of the National Academy of Sciences 108 (11), 4358-4363, 2011 | 69 | 2011 |
| From fish bowl to bedside: The power of zebrafish to unravel melanoma pathogenesis and discover new therapeutics E van Rooijen, M Fazio, L Zon Pigment Cell & Melanoma Research, 2017 | 59 | 2017 |
| Gain-of-function genetic alterations of G9a drive oncogenesis S Kato, QY Weng, ML Insco, KY Chen, S Muralidhar, J Pozniak, JMS Diaz, ... Cancer discovery 10 (7), 980-997, 2020 | 56 | 2020 |
| Mutations in LRRC50 Predispose Zebrafish and Humans to Seminomas SG Basten, EE Davis, AJM Gillis, E van Rooijen, H Stoop, N Babala, ... PLoS genetics 9 (4), e1003384, 2013 | 55 | 2013 |
| Zebrafish as an innovative model for neuroendocrine tumors G Vitale, G Gaudenzi, A Dicitore, F Cotelli, D Ferone, L Persani Endocrine-Related Cancer 21 (1), R67-R83, 2014 | 52 | 2014 |
| Pharmacological HIF2α inhibition improves VHL disease–associated phenotypes in zebrafish model AM Metelo, HR Noonan, X Li, Y Jin, R Baker, L Kamentsky, Y Zhang, ... The Journal of Clinical Investigation 125 (5), 1987-1997, 2015 | 50 | 2015 |
| Balancing the optimal and the feasible: a practical guide for setting up patient registries for the collection of real-world data for health care decision making based on Dutch … S de Groot, N van der Linden, MG Franken, HM Blommestein, ... Value in Health 20 (4), 627-636, 2017 | 46 | 2017 |
| A zebrafish model for VHL and hypoxia signaling E van Rooijen, K Santhakumar, I Logister, E Voest, S Schulte-Merker, ... Methods in cell biology 105, 163-190, 2011 | 36 | 2011 |
