Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis C Lock, G Hermans, R Pedotti, A Brendolan, E Schadt, H Garren, ... Nature medicine 8 (5), 500-508, 2002 | 2075 | 2002 |
The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease D Chabas, SE Baranzini, D Mitchell, CCA Bernard, SR Rittling, ... Science 294 (5547), 1731-1735, 2001 | 1083 | 2001 |
Inhibitory role for GABA in autoimmune inflammation R Bhat, R Axtell, A Mitra, M Miranda, C Lock, RW Tsien, L Steinman Proceedings of the National Academy of Sciences 107 (6), 2580-2585, 2010 | 530 | 2010 |
Clonally expanded B cells in multiple sclerosis bind EBV EBNA1 and GlialCAM TV Lanz, RC Brewer, PP Ho, JS Moon, KM Jude, D Fernandez, ... Nature 603 (7900), 321-327, 2022 | 512 | 2022 |
Gene microarray identification of redox and mitochondrial elements that control resistance or sensitivity to apoptosis DW Voehringer, DL Hirschberg, J Xiao, Q Lu, M Roederer, CB Lock, ... Proceedings of the National Academy of Sciences 97 (6), 2680-2685, 2000 | 336 | 2000 |
Janus-like opposing roles of CD47 in autoimmune brain inflammation in humans and mice MH Han, DH Lundgren, S Jaiswal, M Chao, KL Graham, CS Garris, ... Journal of Experimental Medicine 209 (7), 1325-1334, 2012 | 141 | 2012 |
Expression of HLA-DR4 and human CD4 transgenes in mice determines the variable region beta-chain T-cell repertoire and mediates an HLA-DR-restricted immune response. L Fugger, SA Michie, I Rulifson, CB Lock, GS McDevitt Proceedings of the National Academy of Sciences 91 (13), 6151-6155, 1994 | 116 | 1994 |
Minimum structural requirements for peptide presentation by major histocompatibility complex class II molecules: implications in induction of autoimmunity. AM Gautam, CB Lock, DE Smilek, CI Pearson, L Steinman, HO McDevitt Proceedings of the National Academy of Sciences 91 (2), 767-771, 1994 | 87 | 1994 |
MHC class II sequences of an HLA-DR2 narcoleptic CB Lock, AKL So, KI Welsh, JD Parkes, J Trowsdale Immunogenetics 27, 449-455, 1988 | 78 | 1988 |
Immune factors in narcolepsy N Langdon, C Lock, K Lock, D Lock, R Lock, H Lock, D Lock, JD Jones Sleep 9 (1), 143-148, 1986 | 76 | 1986 |
Analysis of HLA-DR glycoproteins by DNA-mediated gene transfer. Definition of DR2 beta gene products and antigen presentation to T cell clones from leprosy patients. D Wilkinson, RR De Vries, JA Madrigal, CB Lock, JP Morgenstern, ... The Journal of experimental medicine 167 (4), 1442-1458, 1988 | 69 | 1988 |
Selegiline in narcolepsy SE Roselaar, N Langdon, CB Lock, P Jenner, JD Parkes Sleep 10 (5), 491-495, 1986 | 59 | 1986 |
The role of TNFα and lymphotoxin in demyelinating disease C Lock, J Oksenberg, L Steinman Annals of the rheumatic diseases 58 (suppl 1), I121-I128, 1999 | 56 | 1999 |
Antigen Recognition and Peptide‐Mediated Immunotherapy in Autoimmune Disease DE Smilek, CB Lock, HO Mcdevitt Immunological reviews 118 (1), 37-71, 1990 | 49 | 1990 |
Narcolepsy and immunity. JD Parkes, N Langdon, C Lock British Medical Journal (Clinical research ed.) 292 (6517), 359, 1986 | 44 | 1986 |
Prevention of insulin-dependent diabetes mellitus in nonobese diabetic mice by immunogenic but not by tolerated peptides. M Vaysburd, C Lock, H McDevitt The Journal of experimental medicine 182 (3), 897-902, 1995 | 37 | 1995 |
Gene microarray analysis of multiple sclerosis lesions CB Lock, RA Heller Trends in molecular medicine 9 (12), 535-541, 2003 | 34 | 2003 |
The specificity of the antibody response in multiple sclerosis H Garren, L Steinman, C Lock Annals of neurology 43 (1), 4-6, 1998 | 33 | 1998 |
Differential effects of anti-CD20 therapy on CD4 and CD8 T cells and implication of CD20-expressing CD8 T cells in MS disease activity K Shinoda, R Li, A Rezk, I Mexhitaj, KR Patterson, M Kakara, L Zuroff, ... Proceedings of the National Academy of Sciences 120 (3), e2207291120, 2023 | 23 | 2023 |
Ocrelizumab treatment reduced levels of neurofilament light chain and numbers of B cells in the cerebrospinal fluid of patients with relapsing multiple sclerosis in the OBOE … A Cross, J Bennett, HC von Büdingen, R Carruthers, K Edwards, R Fallis, ... Neurology 92 (15_supplement), S56. 008, 2019 | 19 | 2019 |