| Reprogramming human T cell function and specificity with non-viral genome targeting TL Roth, C Puig-Saus, R Yu, E Shifrut, J Carnevale, PJ Li, J Hiatt, J Saco, ... Nature 559 (7714), 405-409, 2018 | 788 | 2018 |
| Diagnostics for SARS-CoV-2 infections BD Kevadiya, J Machhi, J Herskovitz, MD Oleynikov, WR Blomberg, ... Nature materials 20 (5), 593-605, 2021 | 775 | 2021 |
| Easi-CRISPR: a robust method for one-step generation of mice carrying conditional and insertion alleles using long ssDNA donors and CRISPR ribonucleoproteins RM Quadros, H Miura, DW Harms, H Akatsuka, T Sato, T Aida, R Redder, ... Genome biology 18, 1-15, 2017 | 464 | 2017 |
| Easi-CRISPR for creating knock-in and conditional knockout mouse models using long ssDNA donors H Miura, RM Quadros, CB Gurumurthy, M Ohtsuka Nature protocols 13 (1), 195-215, 2018 | 280 | 2018 |
| Mouse genome editing using the CRISPR/Cas system DW Harms, RM Quadros, D Seruggia, M Ohtsuka, G Takahashi, ... Current protocols in human genetics 83 (1), 15.7. 1-15.7. 27, 2014 | 179 | 2014 |
| Arid1b haploinsufficiency disrupts cortical interneuron development and mouse behavior EM Jung, JJ Moffat, J Liu, SM Dravid, CB Gurumurthy, WY Kim Nature neuroscience 20 (12), 1694-1707, 2017 | 166 | 2017 |
| i-GONAD: a robust method for in situ germline genome engineering using CRISPR nucleases M Ohtsuka, M Sato, H Miura, S Takabayashi, M Matsuyama, T Koyano, ... Genome biology 19, 1-15, 2018 | 162 | 2018 |
| Simplified CRISPR tools for efficient genome editing and streamlined protocols for their delivery into mammalian cells and mouse zygotes AM Jacobi, GR Rettig, R Turk, MA Collingwood, SA Zeiner, RM Quadros, ... Methods 121, 16-28, 2017 | 158 | 2017 |
| CRISPR/Cas9-based generation of knockdown mice by intronic insertion of artificial microRNA using longer single-stranded DNA H Miura, CB Gurumurthy, T Sato, M Sato, M Ohtsuka Scientific reports 5 (1), 12799, 2015 | 152 | 2015 |
| Generating mouse models for biomedical research: technological advances CB Gurumurthy, KCK Lloyd Disease models & mechanisms 12 (1), dmm029462, 2019 | 149 | 2019 |
| Cleavage by caspase 8 and mitochondrial membrane association activate the BH3-only protein Bid during TRAIL-induced apoptosis K Huang, J Zhang, KL O’Neill, CB Gurumurthy, RM Quadros, Y Tu, X Luo Journal of Biological Chemistry 291 (22), 11843-11851, 2016 | 147 | 2016 |
| GONAD: Genome-editing via Oviductal Nucleic Acids Delivery system: a novel microinjection independent genome engineering method in mice G Takahashi, CB Gurumurthy, K Wada, H Miura, M Sato, M Ohtsuka Scientific reports 5 (1), 11406, 2015 | 142 | 2015 |
| Human genome-edited hematopoietic stem cells phenotypically correct Mucopolysaccharidosis type I N Gomez-Ospina, SG Scharenberg, N Mostrel, RO Bak, S Mantri, ... Nature communications 10 (1), 4045, 2019 | 113 | 2019 |
| Creation of CRISPR-based germline-genome-engineered mice without ex vivo handling of zygotes by i-GONAD CB Gurumurthy, M Sato, A Nakamura, M Inui, N Kawano, MA Islam, ... Nature protocols 14 (8), 2452-2482, 2019 | 112 | 2019 |
| The notch regulator MAML1 interacts with p53 and functions as a coactivator Y Zhao, RB Katzman, LM Delmolino, I Bhat, Y Zhang, CB Gurumurthy, ... Journal of Biological Chemistry 282 (16), 11969-11981, 2007 | 98 | 2007 |
| Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation CB Gurumurthy, AR O’brien, RM Quadros, J Adams, P Alcaide, S Ayabe, ... Genome biology 20 (1), 1-14, 2019 | 87 | 2019 |
| Mice deficient in Muc4 are resistant to experimental colitis and colitis-associated colorectal cancer S Das, S Rachagani, Y Sheinin, LM Smith, CB Gurumurthy, HK Roy, ... Oncogene 35 (20), 2645-2654, 2016 | 82 | 2016 |
| Distinct subtypes of proprioceptive dorsal root ganglion neurons regulate adaptive proprioception in mice H Wu, C Petitpré, P Fontanet, A Sharma, C Bellardita, RM Quadros, ... Nature communications 12 (1), 1026, 2021 | 72 | 2021 |
| CD4+ effector T cells accelerate Alzheimer’s disease in mice J Machhi, P Yeapuri, Y Lu, E Foster, R Chikhale, J Herskovitz, ... Journal of neuroinflammation 18, 1-23, 2021 | 68 | 2021 |
| CRISPR: a versatile tool for both forward and reverse genetics research CB Gurumurthy, M Grati, M Ohtsuka, SLP Schilit, RM Quadros, XZ Liu Human genetics 135, 971-976, 2016 | 65 | 2016 |
