Direct pharmacological targeting of a mitochondrial ion channel selectively kills tumor cells in vivo L Leanza, M Romio, KA Becker, M Azzolini, L Trentin, A Manago, ... Cancer cell 31 (4), 516-531. e10, 2017 | 154 | 2017 |
Cross-talk between chronic lymphocytic leukemia (CLL) tumor B cells and mesenchymal stromal cells (MSCs): implications for neoplastic cell survival V Trimarco, E Ave, M Facco, G Chiodin, F Frezzato, V Martini, C Gattazzo, ... Oncotarget 6 (39), 42130, 2015 | 53 | 2015 |
In chronic lymphocytic leukemia the JAK2/STAT3 pathway is constitutively activated and its inhibition leads to CLL cell death unaffected by the protective bone marrow … F Severin, F Frezzato, A Visentin, V Martini, V Trimarco, S Carraro, ... Cancers 11 (12), 1939, 2019 | 48 | 2019 |
HSP70/HSF1 axis, regulated via a PI3K/AKT pathway, is a druggable target in chronic lymphocytic leukemia F Frezzato, F Raggi, V Martini, F Severin, V Trimarco, A Visentin, ... International journal of cancer 145 (11), 3089-3100, 2019 | 42 | 2019 |
Cortactin, a Lyn substrate, is a checkpoint molecule at the intersection of BCR and CXCR4 signalling pathway in chronic lymphocytic leukaemia cells V Martini, C Gattazzo, F Frezzato, V Trimarco, M Pizzi, G Chiodin, ... British journal of haematology 178 (1), 81-93, 2017 | 39 | 2017 |
Integrated CLL scoring system, a new and simple index to predict time to treatment and overall survival in patients with chronic lymphocytic leukemia A Visentin, M Facco, F Frezzato, M Castelli, V Trimarco, V Martini, ... Clinical Lymphoma Myeloma and Leukemia 15 (10), 612-620. e5, 2015 | 37 | 2015 |
Prognostic and predictive effect of IGHV mutational status and load in chronic lymphocytic leukemia: focus on FCR and BR treatments A Visentin, M Facco, C Gurrieri, E Pagnin, V Martini, S Imbergamo, ... Clinical Lymphoma Myeloma and Leukemia 19 (10), 678-685. e4, 2019 | 33 | 2019 |
Major infections, secondary cancers and autoimmune diseases occur in different clinical subsets of chronic lymphocytic leukaemia patients A Visentin, S Imbergamo, C Gurrieri, F Frezzato, V Trimarco, V Martini, ... European Journal of Cancer 72, 103-111, 2017 | 31 | 2017 |
Lights and shade of next-generation Pi3k inhibitors in chronic lymphocytic leukemia A Visentin, F Frezzato, F Severin, S Imbergamo, S Pravato, ... OncoTargets and therapy, 9679-9688, 2020 | 21 | 2020 |
Profiling B cell chronic lymphocytic leukemia by reverse phase protein array: Focus on apoptotic proteins F Frezzato, B Accordi, V Trimarco, C Gattazzo, V Martini, G Milani, ... Journal of Leucocyte Biology 100 (5), 1061-1070, 2016 | 20 | 2016 |
Pharmacological modulation of Kv1. 3 potassium channel selectively triggers pathological B lymphocyte apoptosis in vivo in a genetic CLL model F Severin, A Urbani, T Varanita, M Bachmann, M Azzolini, V Martini, ... Journal of Experimental & Clinical Cancer Research 41 (1), 64, 2022 | 18 | 2022 |
Abnormal regulation of BCR signalling by c-Cbl in chronic lymphocytic leukaemia V Martini, F Frezzato, F Severin, F Raggi, V Trimarco, L Martinello, ... Oncotarget 9 (63), 32219, 2018 | 9 | 2018 |
Targeting of HSP70/HSF1 axis abrogates in vitro ibrutinib-resistance in chronic lymphocytic leukemia F Frezzato, A Visentin, F Severin, S Pizzo, E Ruggeri, N Mouawad, ... Cancers 13 (21), 5453, 2021 | 8 | 2021 |
Is It Still Possible to Think about HSP70 as a Therapeutic Target in Onco-Hematological Diseases? N Mouawad, G Capasso, E Ruggeri, L Martinello, F Severin, A Visentin, ... Biomolecules 13 (4), 604, 2023 | 7 | 2023 |
Targeting Brutons Tyrosine Kinase in Chronic Lymphocytic Leukemia at the Crossroad between Intrinsic and Extrinsic Pro-survival Signals F Frezzato, V Trimarco, A Visentin, V Martini, F Severin, M Facco, ... JOURNAL OF LEUKEMIA 4 (01), 207-215, 2016 | 5 | 2016 |
Protective role immunoglobulin replacement therapy in chronic lymphocytic leukemia: FOCUS on subcutaneous immunoglobulin formulations A Visentin, FR Mauro, S Rosati, S Imbergamo, E Scomazzon, S Pravato, ... Blood 132, 4954, 2018 | 4 | 2018 |
Transglutaminase Type 2-MITF axis regulates phenotype switching in skin cutaneous melanoma S Muccioli, V Brillo, T Varanita, F Rossin, E Zaltron, A Velle, G Alessio, ... Cell Death & Disease 14 (10), 704, 2023 | 3 | 2023 |
Focal adhesion kinase activation by calcium‐dependent calpain is involved in chronic lymphocytic leukaemia cell aggressiveness F Severin, N Mouawad, E Ruggeri, A Visentin, L Martinello, E Pagnin, ... British Journal of Haematology 203 (2), 224-236, 2023 | 2 | 2023 |
Biology and Microenvironment A Visentin, F Frezzato, F Severin, M Pizzi, V Martini, F Raggi, ... | 2 | 2018 |
Evaluation of Integrated CLL Scoring System (ICSS) in 420 Patients with Chronic Lymphocytic Leukemia A Visentin, F Frezzato, S Imbergamo, V Trimarco, V Martini, F Severin, ... Blood 128 (22), 5563, 2016 | 2 | 2016 |