Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase NK Kolas, JR Chapman, S Nakada, J Ylanko, R Chahwan, FD Sweeney, ... Science 318 (5856), 1637-1640, 2007 | 1060 | 2007 |
Involvement of mammalian Mus81 in genome integrity and tumor suppression JP McPherson, B Lemmers, R Chahwan, A Pamidi, E Migon, ... Science 304 (5678), 1822-1826, 2004 | 222 | 2004 |
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches JA Welsh, DCI Goberdhan, L O'Driscoll, EI Buzas, C Blenkiron, ... Journal of extracellular vesicles 13 (2), e12404, 2024 | 208 | 2024 |
Eme1 is involved in DNA damage processing and maintenance of genomic stability in mammalian cells J Abraham, B Lemmers, MP Hande, ME Moynahan, C Chahwan, A Ciccia, ... The EMBO journal 22 (22), 6137-6147, 2003 | 157 | 2003 |
The RNF8/RNF168 ubiquitin ligase cascade facilitates class switch recombination S Ramachandran, R Chahwan, RM Nepal, D Frieder, S Panier, S Roa, ... Proceedings of the National Academy of Sciences 107 (2), 809-814, 2010 | 88 | 2010 |
Mammalian Exo1 encodes both structural and catalytic functions that play distinct roles in essential biological processes S Schaetzlein, R Chahwan, E Avdievich, S Roa, K Wei, RL Eoff, ... Proceedings of the National Academy of Sciences 110 (27), E2470-E2479, 2013 | 81 | 2013 |
Overlapping hotspots in CDRs are critical sites for V region diversification L Wei, R Chahwan, S Wang, X Wang, PT Pham, MF Goodman, ... Proceedings of the National Academy of Sciences 112 (7), E728-E737, 2015 | 80 | 2015 |
AIDing antibody diversity by error-prone mismatch repair R Chahwan, W Edelmann, MD Scharff, S Roa Seminars in immunology 24 (4), 293-300, 2012 | 72 | 2012 |
Encyclopedia of immunobiology MJH Ratcliffe Academic Press, 2016 | 61 | 2016 |
The MutSβ complex is a modulator of p53-driven tumorigenesis through its functions in both DNA double-strand break repair and mismatch repair JMM van Oers, Y Edwards, R Chahwan, W Zhang, C Smith, X Pechuan, ... Oncogene 33 (30), 3939-3946, 2014 | 59 | 2014 |
Aicardi–Goutieres syndrome: from patients to genes and beyond C Chahwan, R Chahwan Clinical genetics 81 (5), 413-420, 2012 | 52 | 2012 |
Crosstalk between genetic and epigenetic information through cytosine deamination R Chahwan, SN Wontakal, S Roa Trends in genetics 26 (10), 443-448, 2010 | 52 | 2010 |
The multidimensional nature of epigenetic information and its role in disease R Chahwan, SN Wontakal, S Roa Discovery medicine 11 (58), 233-243, 2011 | 50 | 2011 |
A source of the single-stranded DNA substrate for activation-induced deaminase during somatic hypermutation X Wang, M Fan, S Kalis, L Wei, MD Scharff Nature communications 5 (1), 4137, 2014 | 41 | 2014 |
APOBECs orchestrate genomic and epigenomic editing across health and disease K Cervantes-Gracia, A Gramalla-Schmitz, J Weischedel, R Chahwan Trends in Genetics 37 (11), 1028-1043, 2021 | 34 | 2021 |
The ATPase activity of MLH1 is required to orchestrate DNA double-strand breaks and end processing during class switch recombination R Chahwan, JMM van Oers, E Avdievich, C Zhao, W Edelmann, ... Journal of Experimental Medicine 209 (4), 671-678, 2012 | 34 | 2012 |
Mismatch-mediated error prone repair at the immunoglobulin genes R Chahwan, W Edelmann, MD Scharff, S Roa Biomedicine & Pharmacotherapy 65 (8), 529-536, 2011 | 34 | 2011 |
Epigenomic modifications mediating antibody maturation EC Sheppard, RB Morrish, MJ Dillon, R Leyland, R Chahwan Frontiers in immunology 9, 333430, 2018 | 30 | 2018 |
Somatic hypermutation: the molecular mechanisms underlying the production of effective high-affinity antibodies A Martin, R Chahwan, JY Parsa, MD Scharff Molecular Biology of B Cells, 363-388, 2015 | 30 | 2015 |
Modelling liver cancer microenvironment using a novel 3D culture system A Al Hrout, K Cervantes-Gracia, A Amin*, R Chahwan* Scientific Reports 12 (8003), 1-14, 2022 | 29 | 2022 |