| A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication K Ratia, S Pegan, J Takayama, K Sleeman, M Coughlin, S Baliji, ... Proceedings of the National Academy of Sciences 105 (42), 16119-16124, 2008 | 495 | 2008 |
| Hit identification and optimization in virtual screening: Practical recommendations based on a critical literature analysis: Miniperspective T Zhu, S Cao, PC Su, R Patel, D Shah, HB Chokshi, R Szukala, ... Journal of medicinal chemistry 56 (17), 6560-6572, 2013 | 310 | 2013 |
| Multiple Novel Inhibitors of the NorA Multidrug Transporter of Staphylococcus aureus PN Markham, E Westhaus, K Klyachko, ME Johnson, AA Neyfakh Antimicrobial agents and chemotherapy 43 (10), 2404-2408, 1999 | 301 | 1999 |
| Severe acute respiratory syndrome coronavirus papain-like novel protease inhibitors: design, synthesis, protein− ligand X-ray structure and biological evaluation AK Ghosh, J Takayama, KV Rao, K Ratia, R Chaudhuri, DC Mulhearn, ... Journal of medicinal chemistry 53 (13), 4968-4979, 2010 | 165 | 2010 |
| Design and synthesis of peptidomimetic severe acute respiratory syndrome chymotrypsin-like protease inhibitors AK Ghosh, K Xi, K Ratia, BD Santarsiero, W Fu, BH Harcourt, PA Rota, ... Journal of medicinal chemistry 48 (22), 6767-6771, 2005 | 160 | 2005 |
| Identification of novel small molecule inhibitors against NS2B/NS3 serine protease from Zika virus H Lee, J Ren, S Nocadello, AJ Rice, I Ojeda, S Light, G Minasov, J Vargas, ... Antiviral research 139, 49-58, 2017 | 139 | 2017 |
| Structure-based design, synthesis, and biological evaluation of a series of novel and reversible inhibitors for the severe acute respiratory syndrome− coronavirus papain-like … AK Ghosh, J Takayama, Y Aubin, K Ratia, R Chaudhuri, Y Baez, ... Journal of medicinal chemistry 52 (16), 5228-5240, 2009 | 139 | 2009 |
| Design, synthesis and antiviral efficacy of a series of potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitors AK Ghosh, G Gong, V Grum-Tokars, DC Mulhearn, SC Baker, M Coughlin, ... Bioorganic & medicinal chemistry letters 18 (20), 5684-5688, 2008 | 138 | 2008 |
| Inhibitor recognition specificity of MERS-CoV papain-like protease may differ from that of SARS-CoV H Lee, H Lei, BD Santarsiero, JL Gatuz, S Cao, AJ Rice, K Patel, ... ACS chemical biology 10 (6), 1456-1465, 2015 | 134 | 2015 |
| Ligand efficiency indices for an effective mapping of chemico-biological space: the concept of an atlas-like representation C Abad-Zapatero, O Perišić, J Wass, AP Bento, J Overington, ... Drug discovery today 15 (19-20), 804-811, 2010 | 121 | 2010 |
| Design and synthesis of a CD4 beta-turn mimetic that inhibits human immunodeficiency virus envelope glycoprotein gp120 binding and infection of human lymphocytes. S Chen, RA Chrusciel, H Nakanishi, A Raktabutr, ME Johnson, A Sato, ... Proceedings of the National Academy of Sciences 89 (13), 5872-5876, 1992 | 116 | 1992 |
| Cytotoxic and antimalarial bisbenzylisoquinoline alkaloids from Cyclea barbata LZ Lin, HL Shieh, CK Angerhofer, JM Pezzuto, GA Cordell, L Xue, ... Journal of natural products 56 (1), 22-29, 1993 | 115 | 1993 |
| Comparison of radii sets, entropy, QM methods, and sampling on MM‐PBSA, MM‐GBSA, and QM/MM‐GBSA ligand binding energies of F. tularensis enoyl‐ACP … PC Su, CC Tsai, S Mehboob, KE Hevener, ME Johnson Journal of computational chemistry 36 (25), 1859-1873, 2015 | 114 | 2015 |
| Structure-based design, synthesis, and biological evaluation of peptidomimetic SARS-CoV 3CLpro inhibitors AK Ghosh, K Xi, V Grum-Tokars, X Xu, K Ratia, W Fu, KV Houser, ... Bioorganic & medicinal chemistry letters 17 (21), 5876-5880, 2007 | 113 | 2007 |
| Polyoxypregnanes from Marsdenia tenacissima. SQ Luo, LZ Lin, GA Cordell, L Xue, ME Johnson | 111 | 1993 |
| [D-TRP32] neuropeptide Y: a competitive antagonist of NPY in rat hypothalamus A Balasubramaniam, S Sheriff, ME Johnson, M Prabhakaran, Y Huang, ... Journal of medicinal chemistry 37 (6), 811-815, 1994 | 108 | 1994 |
| Inhibition of MptpB phosphatase from Mycobacterium tuberculosis impairs mycobacterial survival in macrophages NJ Beresford, D Mulhearn, B Szczepankiewicz, G Liu, ME Johnson, ... Journal of antimicrobial chemotherapy 63 (5), 928-936, 2009 | 100 | 2009 |
| Effects of ligands and organic phosphates on functional properties of human adult hemoglobin ME Johnson, C Ho Biochemistry 13 (18), 3653-3661, 1974 | 79 | 1974 |
| Discovery of a novel and potent class of F. tularensis enoyl-reductase (FabI) inhibitors by molecular shape and electrostatic matching KE Hevener, S Mehboob, PC Su, K Truong, T Boci, J Deng, M Ghassemi, ... Journal of medicinal chemistry 55 (1), 268-279, 2012 | 75 | 2012 |
| Identification of novel drug scaffolds for inhibition of SARS-CoV 3-Chymotrypsin-like protease using virtual and high-throughput screenings H Lee, A Mittal, K Patel, JL Gatuz, L Truong, J Torres, DC Mulhearn, ... Bioorganic & medicinal chemistry 22 (1), 167-177, 2014 | 68 | 2014 |
Shahila MehboobUniversity of Illinois at Chicago在 uic.edu 的电子邮件经过验证
