关注
Sofya Lushchekina
Sofya Lushchekina
Emanuel Institute of Biochemical Physics, RAS; Chemical Department, Lomonosov Moscow State
在 deom.chph.ras.ru 的电子邮件经过验证
标题
引用次数
引用次数
年份
Conjugates of γ-Carbolines and Phenothiazine as new selective inhibitors of butyrylcholinesterase and blockers of NMDA receptors for Alzheimer Disease
GF Makhaeva, SV Lushchekina, NP Boltneva, VB Sokolov, VV Grigoriev, ...
Scientific reports 5 (1), 13164, 2015
1052015
New evidence for dual binding site inhibitors of acetylcholinesterase as improved drugs for treatment of Alzheimer's disease
I Zueva, J Dias, S Lushchekina, V Semenov, M Mukhamedyarov, ...
Neuropharmacology 155, 131-141, 2019
802019
Novel conjugates of aminoadamantanes with carbazole derivatives as potential multitarget agents for AD treatment
SO Bachurin, EF Shevtsova, GF Makhaeva, VV Grigoriev, NP Boltneva, ...
Scientific Reports 7 (1), 45627, 2017
792017
Synthesis, molecular docking and biological evaluation of N, N-disubstituted 2-aminothiazolines as a new class of butyrylcholinesterase and carboxylesterase inhibitors
GF Makhaeva, NP Boltneva, SV Lushchekina, OG Serebryakova, ...
Bioorganic & Medicinal Chemistry 24 (5), 1050-1062, 2016
752016
Effects of viscosity and osmotic stress on the reaction of human butyrylcholinesterase with cresyl saligenin phosphate, a toxicant related to aerotoxic syndrome: kinetic and …
P Masson, S Lushchekina, LM Schopfer, O Lockridge
Biochemical Journal 454 (3), 387-399, 2013
682013
Characterization of a complete cycle of acetylcholinesterase catalysis by ab initio QM/MM modeling
AV Nemukhin, SV Lushchekina, AV Bochenkova, AA Golubeva, ...
Journal of Molecular Modeling 14, 409-416, 2008
682008
The SOL docking package for computer-aided drug design
AN Romanov, FV Grigor'ev, AV Sulimov, SV Lushchekina, YB Martynov, ...
Numerical methods and programming 9 (3), 213-233, 2008
58*2008
Conjugates of tacrine and 1, 2, 4-thiadiazole derivatives as new potential multifunctional agents for Alzheimer’s disease treatment: Synthesis, quantum-chemical …
GF Makhaeva, NV Kovaleva, NP Boltneva, SV Lushchekina, ...
Bioorganic Chemistry 94, 103387, 2020
572020
9-Substituted acridine derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors possessing antioxidant activity for Alzheimer's disease treatment
GF Makhaeva, SV Lushchekina, NP Boltneva, OG Serebryakova, ...
Bioorganic & medicinal chemistry 25 (21), 5981-5994, 2017
552017
Emergence of catalytic bioscavengers against organophosphorus agents
P Masson, SV Lushchekina
Chemico-biological interactions 259, 319-326, 2016
512016
Mixed implicit/explicit solvation models in quantum mechanical calculations of binding enthalpy for protein–ligand complexes
E Nikitina, V Sulimov, F Grigoriev, O Kondakova, S Luschekina
International journal of quantum chemistry 106 (8), 1943-1963, 2006
502006
Optimization of cholinesterase-based catalytic bioscavengers against organophosphorus agents
SV Lushchekina, LM Schopfer, BL Grigorenko, AV Nemukhin, ...
Frontiers in pharmacology 9, 211, 2018
492018
Slow-binding inhibition of acetylcholinesterase by an alkylammonium derivative of 6-methyluracil: mechanism and possible advantages for myasthenia gravis treatment
AD Kharlamova, SV Lushchekina, KA Petrov, ED Kots, F Nachon, ...
Biochemical Journal 473 (9), 1225-1236, 2016
492016
Cholinesterase and carboxylesterase inhibitors as pharmacological agents
GF Makhaeva, EV Rudakova, NV Kovaleva, SV Lushchekina, ...
Russian Chemical Bulletin 68, 967-984, 2019
482019
Quantum chemical modelling in the research of molecular mechanisms of enzymatic catalysis
AV Nemukhin, BL Grigorenko, SV Lushchekina, SD Varfolomeev
Russian Chemical Reviews 81 (11), 1011, 2012
46*2012
Molecular modeling of mesoscopic composite systems. Structure and micromechanical properties
YG Yanovsky, EA Nikitina, YN Karnet, KK Valiev, SV Luschekina
PHYSICAL MESOMECHANICS 8 (5/6), 55, 2005
46*2005
Esterase profiles of organophosphorus compounds in vitro predict their behavior in vivo
GF Makhaeva, EV Rudakova, OG Serebryakova, AY Aksinenko, ...
Chemico-Biological Interactions 259, 332-342, 2016
432016
6‐Methyluracil Derivatives as Bifunctional Acetylcholinesterase Inhibitors for the Treatment of Alzheimer's Disease
VE Semenov, IV Zueva, MA Mukhamedyarov, SV Lushchekina, ...
ChemMedChem 10 (11), 1863-1874, 2015
432015
Overview of novel multifunctional agents based on conjugates of γ-carbolines, carbazoles, tetrahydrocarbazoles, phenothiazines, and aminoadamantanes for treatment of Alzheimer …
GF Makhaeva, EF Shevtsova, NP Boltneva, SV Lushchekina, ...
Chemico-Biological Interactions 308, 224-234, 2019
402019
Focused design of polypharmacophoric neuroprotective compounds: Conjugates of γ-carbolines with carbazole derivatives and tetrahydrocarbazole
GF Makhaeva, VB Sokolov, EF Shevtsova, NV Kovaleva, SV Lushchekina, ...
Pure and Applied Chemistry 89 (8), 1167-1184, 2017
402017
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