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Matthias Hochgürtel
Matthias Hochgürtel
TH Köln
在 th-koeln.de 的电子邮件经过验证 - 首页
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引用次数
引用次数
年份
A new class of potent matrix metalloproteinase 13 inhibitors for potential treatment of osteoarthritis: Evidence of histologic and clinical efficacy without musculoskeletal …
VM Baragi, G Becher, AM Bendele, R Biesinger, H Bluhm, J Boer, H Deng, ...
Arthritis & Rheumatism: Official Journal of the American College of …, 2009
2252009
Fragment-based approaches in drug discovery
DA Erlanson, W Jahnke
Wiley-VCH, 2006
1982006
Target-induced formation of neuraminidase inhibitors from in vitro virtual combinatorial libraries
M Hochgürtel, H Kroth, D Piecha, MW Hofmann, C Nicolau, S Krause, ...
Proceedings of the National Academy of Sciences 99 (6), 3382-3387, 2002
1852002
Structure–activity relationship of inhibition of fish feeding by sponge-derived and synthetic pyrrole–imidazole alkaloids
T Lindel, H Hoffmann, M Hochgürtel, JR Pawlik
Journal of Chemical Ecology 26, 1477-1496, 2000
1282000
Ketones as building blocks for dynamic combinatorial libraries: highly active neuraminidase inhibitors generated via selection pressure of the biological target
M Hochgürtel, R Biesinger, H Kroth, D Piecha, MW Hofmann, S Krause, ...
Journal of medicinal chemistry 46 (3), 356-358, 2003
1252003
Synthesis of the Marine Natural Product Oroidin and Its Z-Isomer
T Lindel, M Hochgürtel
The Journal of Organic Chemistry 65 (9), 2806-2809, 2000
862000
Fragment-based approaches in drug discovery
VM Krishnamurthy, LA Estroff, GM Whitesides
Multivalency in Ligand Design, Wiley-VCH, 2006
71*2006
Synthesis of the Marine Natural Product Nα-(4-Bromopyrrolyl-2-carbonyl)-l-homoarginine, a Putative Biogenetic Precursor of the Pyrrole−Imidazole Alkaloids
T Lindel, M Hochgürtel, M Assmann, M Köck
Journal of natural products 63 (11), 1566-1569, 2000
622000
Decomposition of oroidin in DMSO/TFA
T Lindel, G Breckle, M Hochgürtel, C Volk, A Grube, M Köck
Tetrahedron letters 45 (44), 8149-8152, 2004
422004
The alkyne pathway to keramadine from the marine sponge Agelas sp.
T Lindel, M Hochgürtel
Tetrahedron letters 39 (17), 2541-2544, 1998
351998
Heterobicyclic metalloprotease inhibitors
C Steeneck, C Gege, F Richter, H Kroth, M Hochguertel, M Essers, ...
US Patent App. 11/602,140, 2007
332007
Multicyclic bis-amide MMP inhibitors
T Powers, C Steeneck, R Biesinger, H Bluhm, H Deng, R Dodd, ...
US Patent App. 11/324,037, 2006
302006
Metalloprotease inhibitors containing a heterocyclic moiety
C Gege, H Bluhm, M Hochgurtel, M Schneider, C Chevrier, A Taveras
US Patent App. 12/074,917, 2008
272008
Total Synthesis of (+)‐Erogorgiaene and the Pseudopterosin A− F Aglycone via Enantioselective Cobalt‐Catalyzed Hydrovinylation
S Movahhed, J Westphal, A Kempa, CE Schumacher, J Sperlich, ...
Chemistry–A European Journal 27 (45), 11574-11579, 2021
122021
Heterobicyclic metalloprotease inhibitors
B Gallagher, J Van Veldhuizen, X Wu, H Deng, I Sucholeiki, ...
US Patent App. 11/602,116, 2007
112007
Glycosylation of caffeic acid and structural analogues catalyzed by novel glucansucrases from Leuconostoc and Weissella species
J Nolte, A Kempa, A Schlockermann, M Hochgürtel, U Schörken
Biocatalysis and Agricultural Biotechnology 19, 101114, 2019
102019
Fragment-based approaches in drug discovery
M Hochgürtel, JM Lehn
Wiley-VCH, Weinheim.(c) Ramström O, Lehn JM (2007) Comprehensive medicinal …, 2006
92006
Dipeptidyl peptidase-iv inhibitors
H Kroth, T Feuerstein, F Richter, J Boer, M Essers, B Nolte, M Schneider, ...
US Patent App. 12/492,254, 2010
62010
Dynamic combinatorial diversity in drug discovery
M Hochgürtel, JM Lehn
Fragment-based Approaches in Drug Discovery 34, 341-364, 2006
62006
Heterobicyclic metalloprotease inhibitors
H Bluhm, M Hochgurtel, H Kroth, M Essers, C Gege, F Richter, A Taveras
US Patent App. 11/986,586, 2008
52008
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