A five-repeat micro-dystrophin gene ameliorated dystrophic phenotype in the severe DBA/2J-mdx model of Duchenne muscular dystrophy CH Hakim, NB Wasala, X Pan, K Kodippili, Y Yue, K Zhang, G Yao, ... Molecular Therapy-Methods & Clinical Development 6, 216-230, 2017 | 111 | 2017 |
Cas9-specific immune responses compromise local and systemic AAV CRISPR therapy in multiple dystrophic canine models CH Hakim, SRP Kumar, DO Pérez-López, NB Wasala, D Zhang, Y Yue, ... Nature communications 12 (1), 6769, 2021 | 98 | 2021 |
AAV CRISPR editing rescues cardiac and muscle function for 18 months in dystrophic mice CH Hakim, NB Wasala, CE Nelson, LP Wasala, Y Yue, JA Louderman, ... JCI insight 3 (23), 2018 | 95 | 2018 |
Evaluation of muscle function of the extensor digitorum longus muscle ex vivo and tibialis anterior muscle in situ in mice CH Hakim, NB Wasala, D Duan JoVE (Journal of Visualized Experiments), e50183, 2013 | 91 | 2013 |
AAV micro-dystrophin gene therapy alleviates stress-induced cardiac death but not myocardial fibrosis in> 21-m-old mdx mice, an end-stage model of Duchenne muscular dystrophy … B Bostick, JH Shin, Y Yue, NB Wasala, Y Lai, D Duan Journal of molecular and cellular cardiology 53 (2), 217-222, 2012 | 79 | 2012 |
The evolution of heart gene delivery vectors NB Wasala, JH Shin, D Duan The journal of gene medicine 13 (10), 557-565, 2011 | 68 | 2011 |
AAV9 edits muscle stem cells in normal and dystrophic adult mice ME Nance, R Shi, CH Hakim, NB Wasala, Y Yue, X Pan, T Zhang, ... Molecular Therapy 27 (9), 1568-1585, 2019 | 59 | 2019 |
Exclusive skeletal muscle correction does not modulate dystrophic heart disease in the aged mdx model of Duchenne cardiomyopathy NB Wasala, B Bostick, Y Yue, D Duan Human Molecular Genetics 22 (13), 2634-2641, 2013 | 46 | 2013 |
Pyrosequencing and characterization of immune response genes from the American dog tick, Dermacentor variabilis (L.) DC Jaworski, Z Zou, CJ Bowen, NB Wasala, R Madden, Y Wang, ... Insect molecular biology 19 (5), 617-630, 2010 | 45 | 2010 |
Single SERCA2a therapy ameliorated dilated cardiomyopathy for 18 months in a mouse model of Duchenne muscular dystrophy NB Wasala, Y Yue, W Lostal, LP Wasala, N Niranjan, RJ Hajjar, GJ Babu, ... Molecular therapy 28 (3), 845-854, 2020 | 41 | 2020 |
Histology validation of mapping depth-resolved cardiac fiber orientation in fresh mouse heart using optical polarization tractography Y Wang, K Zhang, NB Wasala, X Yao, D Duan, G Yao Biomedical optics express 5 (8), 2843-2855, 2014 | 40 | 2014 |
Partial restoration of cardiac function with ΔPDZ nNOS in aged mdx model of Duchenne cardiomyopathy Y Lai, J Zhao, Y Yue, NB Wasala, D Duan Human Molecular Genetics 23 (12), 3189-3199, 2014 | 39 | 2014 |
Macrophage migration inhibitory factor expression and protein localization in Amblyomma americanum (Ixodidae) CJ Bowen, DC Jaworski, NB Wasala, LB Coons Experimental and Applied Acarology 50, 343-352, 2010 | 28 | 2010 |
Duchenne muscular dystrophy animal models for high-throughput drug discovery and precision medicine NB Wasala, SJ Chen, D Duan Expert opinion on drug discovery 15 (4), 443-456, 2020 | 27 | 2020 |
Optical polarization tractography revealed significant fiber disarray in skeletal muscles of a mouse model for Duchenne muscular dystrophy Y Wang, K Zhang, NB Wasala, D Duan, G Yao Biomedical Optics Express 6 (2), 347-352, 2015 | 22 | 2015 |
Uniform low-level dystrophin expression in the heart partially preserved cardiac function in an aged mouse model of Duchenne cardiomyopathy NB Wasala, Y Yue, J Vance, D Duan Journal of molecular and cellular cardiology 102, 45-52, 2017 | 20 | 2017 |
Cardiac-specific expression of ΔH2-R15 mini-dystrophin normalized all electrocardiogram abnormalities and the end-diastolic volume in a 23-month-old mouse model of Duchenne … NB Wasala, JH Shin, Y Lai, Y Yue, F Montanaro, D Duan Human gene therapy 29 (7), 737-748, 2018 | 19 | 2018 |
Genomic removal of a therapeutic mini-dystrophin gene from adult mice elicits a Duchenne muscular dystrophy-like phenotype NB Wasala, Y Lai, JH Shin, J Zhao, Y Yue, D Duan Human Molecular Genetics 25 (13), 2633-2644, 2016 | 19 | 2016 |
Identification and expression of macrophage migration inhibitory factor in Sarcoptes scabiei NM Cote, DC Jaworski, NB Wasala, MS Morgan, LG Arlian Experimental parasitology 135 (1), 175-181, 2013 | 17 | 2013 |
Proteomic analysis identifies key differences in the cardiac interactomes of dystrophin and micro-dystrophin H Wang, E Marrosu, D Brayson, NB Wasala, EK Johnson, CS Scott, Y Yue, ... Human Molecular Genetics 30 (14), 1321-1336, 2021 | 16 | 2021 |