Dissociation of pentameric to monomeric C-reactive protein on activated platelets localizes inflammation to atherosclerotic plaques SU Eisenhardt, J Habersberger, A Murphy, YC Chen, KJ Woollard, ... Circulation research 105 (2), 128-137, 2009 | 314 | 2009 |
Conformation-specific blockade of the integrin GPIIb/IIIa: a novel antiplatelet strategy that selectively targets activated platelets M Schwarz, G Meade, P Stoll, J Ylanne, N Bassler, YC Chen, ... Circulation research 99 (1), 25-33, 2006 | 237 | 2006 |
Studies of χ (2)/χ (3) tensors in submicron-scaled bio-tissues by polarization harmonics optical microscopy SW Chu, SY Chen, GW Chern, TH Tsai, YC Chen, BL Lin, CK Sun Biophysical journal 86 (6), 3914-3922, 2004 | 237 | 2004 |
A novel mouse model of atherosclerotic plaque instability for drug testing and mechanistic/therapeutic discoveries using gene and microRNA expression profiling YC Chen, AV Bui, J Diesch, R Manasseh, C Hausding, J Rivera, I Haviv, ... Circulation research 113 (3), 252-265, 2013 | 204 | 2013 |
Near-infrared autofluorescence induced by intraplaque hemorrhage and heme degradation as marker for high-risk atherosclerotic plaques NM Htun, YC Chen, B Lim, T Schiller, GJ Maghzal, AL Huang, KD Elgass, ... Nature communications 8 (1), 75, 2017 | 130 | 2017 |
Thrombus-targeted theranostic microbubbles: a new technology towards concurrent rapid ultrasound diagnosis and bleeding-free fibrinolytic treatment of thrombosis X Wang, Y Gkanatsas, J Palasubramaniam, JD Hohmann, YC Chen, ... Theranostics 6 (5), 726, 2016 | 129 | 2016 |
Myeloperoxidase is a potential molecular imaging and therapeutic target for the identification and stabilization of high-risk atherosclerotic plaque I Rashid, GJ Maghzal, YC Chen, D Cheng, J Talib, D Newington, M Ren, ... European heart journal 39 (35), 3301-3310, 2018 | 120 | 2018 |
Atherosclerotic plaque rupture: identifying the straw that breaks the camel’s back YC Chen, AL Huang, TS Kyaw, A Bobik, K Peter Arteriosclerosis, thrombosis, and vascular biology 36 (8), e63-e72, 2016 | 100 | 2016 |
Targeting ligand-induced binding sites on GPIIb/IIIa via single-chain antibody allows effective anticoagulation without bleeding time prolongation P Stoll, N Bassler, CE Hagemeyer, SU Eisenhardt, YC Chen, R Schmidt, ... Arteriosclerosis, thrombosis, and vascular biology 27 (5), 1206-1212, 2007 | 99 | 2007 |
Plasma levels of trimethylamine-N-oxide can be increased with ‘healthy’and ‘unhealthy’diets and do not correlate with the extent of atherosclerosis but with plaque instability YC Koay, YC Chen, JA Wali, AWS Luk, M Li, H Doma, R Reimark, ... Cardiovascular research 117 (2), 435-449, 2021 | 96 | 2021 |
Thrombin-induced MCP-1 expression involves activation of the p22phox-containing NADPH oxidase in human vascular smooth muscle cells RP Brandes, C Viedt, K Nguyen, S Beer, J Kreuzer, R Busse, A Görlach Thrombosis and haemostasis 85 (06), 1104-1110, 2001 | 93 | 2001 |
Amyloid plaques dissociate pentameric to monomeric C‐reactive protein: a novel pathomechanism driving cortical inflammation in Alzheimer's disease? F Strang, A Scheichl, YC Chen, X Wang, NM Htun, N Bassler, ... Brain Pathology 22 (3), 337-346, 2012 | 92 | 2012 |
Multiharmonic-generation biopsy of skin SCK Chen CC, Chu SW, Tsai TH, Chen YC, Lin BL. Opt Lett. 28, 2488-2490, 2003 | 91 | 2003 |
Transcatheter aortic valve implantation represents an anti-inflammatory therapy via reduction of shear stress–induced, piezo-1–mediated monocyte activation S Baratchi, MTK Zaldivia, M Wallert, J Loseff-Silver, S Al-Aryahi, J Zamani, ... Circulation 142 (11), 1092-1105, 2020 | 87 | 2020 |
A randomized controlled trial to isolate the effects of fasting and energy restriction on weight loss and metabolic health in lean adults I Templeman, HA Smith, E Chowdhury, YC Chen, H Carroll, ... Science translational medicine 13 (598), eabd8034, 2021 | 82 | 2021 |
Protective role for toll-like receptor-9 in the development of atherosclerosis in apolipoprotein E–deficient mice C Koulis, YC Chen, C Hausding, I Ahrens, TS Kyaw, C Tay, T Allen, ... Arteriosclerosis, thrombosis, and vascular biology 34 (3), 516-525, 2014 | 80 | 2014 |
HMGB1 binds to activated platelets via the receptor for advanced glycation end products and is present in platelet rich human coronary artery thrombi I Ahrens, YC Chen, D Topcic, M Bode, D Haenel, CE Hagemeyer, ... Thrombosis and haemostasis 114 (11), 994-1003, 2015 | 63 | 2015 |
Coinhibitory suppression of T cell activation by CD40 protects against obesity and adipose tissue inflammation in mice D Wolf, F Jehle, NA Michel, EN Bukosza, J Rivera, YC Chen, N Hoppe, ... Circulation 129 (23), 2414-2425, 2014 | 62 | 2014 |
Urine proteome analysis reflects atherosclerotic disease in an ApoE−/− mouse model and allows the discovery of new candidate biomarkers in mouse and human atherosclerosis C Von Zur Muhlen, E Schiffer, C Sackmann, P Zürbig, I Neudorfer, A Zirlik, ... Molecular & Cellular Proteomics 11 (7), M111. 013847-1-M111. 013847-13, 2012 | 62 | 2012 |
GPVI and GPIbα mediate staphylococcal superantigen-like protein 5 (SSL5) induced platelet activation and direct toward glycans as potential inhibitors H Hu, PCJ Armstrong, E Khalil, YC Chen, A Straub, M Li, J Soosairajah, ... PloS one 6 (4), e19190, 2011 | 58 | 2011 |