A proteome-scale map of the human interactome network T Rolland, M Taşan, B Charloteaux, SJ Pevzner, Q Zhong, N Sahni, S Yi, ... Cell 159 (5), 1212-1226, 2014 | 1461 | 2014 |
A reference map of the human binary protein interactome K Luck, DK Kim, L Lambourne, K Spirohn, BE Begg, W Bian, R Brignall, ... Nature, 1-7, 2020 | 958 | 2020 |
Annotation transfer between genomes: protein–protein interologs and protein–DNA regulogs H Yu, NM Luscombe, HX Lu, X Zhu, Y Xia, JDJ Han, N Bertin, S Chung, ... Genome research 14 (6), 1107-1118, 2004 | 686 | 2004 |
Diverse cellular functions of the Hsp90 molecular chaperone uncovered using systems approaches AJ McClellan, Y Xia, AM Deutschbauer, RW Davis, M Gerstein, J Frydman Cell 131 (1), 121-135, 2007 | 582 | 2007 |
Widespread Macromolecular Interaction Perturbations in Human Genetic Disorders N Sahni, S Yi, M Taipale, JIF Bass, J Coulombe-Huntington, F Yang, ... Cell 161 (3), 647-660, 2015 | 570 | 2015 |
Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing X Yang, J Coulombe-Huntington, S Kang, GM Sheynkman, T Hao, ... Cell 164 (4), 805-817, 2016 | 555 | 2016 |
Relating three-dimensional structures to protein networks provides evolutionary insights PM Kim, LJ Lu, Y Xia, MB Gerstein Science 314 (5807), 1938, 2006 | 555 | 2006 |
Defining the TRiC/CCT interactome links chaperonin function to stabilization of newly made proteins with complex topologies AY Yam, Y Xia, HTJ Lin, A Burlingame, M Gerstein, J Frydman Nature structural & molecular biology 15 (12), 1255-1262, 2008 | 436 | 2008 |
Assessing the limits of genomic data integration for predicting protein networks LJ Lu, Y Xia, A Paccanaro, H Yu, M Gerstein Genome research 15 (7), 945-953, 2005 | 266 | 2005 |
Genome-wide prioritization of disease genes and identification of disease-disease associations from an integrated human functional linkage network B Linghu, ES Snitkin, Z Hu, Y Xia, C DeLisi Genome Biol 10 (9), R91, 2009 | 264 | 2009 |
The role of disorder in interaction networks: a structural analysis PM Kim, A Sboner, Y Xia, M Gerstein Molecular Systems Biology 4 (1), 179, 2008 | 264 | 2008 |
Ab initio construction of protein tertiary structures using a hierarchical approach Y Xia, ES Huang, M Levitt, R Samudrala Journal of molecular biology 300 (1), 171-185, 2000 | 218 | 2000 |
Structural determinants of protein evolution are context-sensitive at the residue level EA Franzosa, Y Xia Molecular biology and evolution 26 (10), 2387-2395, 2009 | 196 | 2009 |
Analyzing cellular biochemistry in terms of molecular networks Y Xia, H Yu, R Jansen, M Seringhaus, S Baxter, D Greenbaum, H Zhao, ... Annual review of biochemistry 73 (1), 1051-1087, 2004 | 173 | 2004 |
Use of thioredoxin as a reporter to identify a subset of Escherichia coli signal sequences that promote signal recognition particle-dependent translocation D Huber, D Boyd, Y Xia, MH Olma, M Gerstein, J Beckwith Journal of bacteriology 187 (9), 2983-2991, 2005 | 171 | 2005 |
Ab initio protein structure prediction using a combined hierarchical approach R Samudrala, Y Xia, E Huang, M Levitt Proteins: Structure, Function, and Bioinformatics 37 (S3), 194-198, 1999 | 149 | 1999 |
Structural principles within the human-virus protein-protein interaction network EA Franzosa, Y Xia Proceedings of the National Academy of Sciences 108 (26), 10538-10543, 2011 | 146 | 2011 |
A proteome-wide fission yeast interactome reveals network evolution principles from yeasts to human TV Vo, J Das, MJ Meyer, NA Cordero, N Akturk, X Wei, BJ Fair, ... Cell 164 (1), 310-323, 2016 | 118 | 2016 |
Simulating protein evolution in sequence and structure space Y Xia, M Levitt Current opinion in structural biology 14 (2), 202-207, 2004 | 113 | 2004 |
A High-Resolution Genome-Wide CRISPR/Cas9 Viability Screen Reveals Structural Features and Contextual Diversity of the Human Cell-Essential Proteome T Bertomeu, J Coulombe-Huntington, A Chatr-aryamontri, KG Bourdages, ... Molecular and cellular biology 38 (1), e00302-17, 2018 | 96 | 2018 |