A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease M Björkqvist, EJ Wild, J Thiele, A Silvestroni, R Andre, N Lahiri, E Raibon, ... The Journal of experimental medicine 205 (8), 1869, 2008 | 730 | 2008 |
Stem-cell-based, tissue engineered tracheal replacement in a child: a 2-year follow-up study MJ Elliott, P De Coppi, S Speggiorin, D Roebuck, CR Butler, E Samuel, ... The Lancet 380 (9846), 994-1000, 2012 | 554 | 2012 |
Human mesenchymal stem cells induce T cell anergy and downregulate T cell allo-responses via the TH2 pathway: relevance to tissue engineering human heart valves P Batten, P Sarathchandra, JW Antoniw, SS Tay, MW Lowdell, PM Taylor, ... Tissue engineering 12 (8), 2263-2273, 2006 | 286 | 2006 |
Directly selected cytomegalovirus-reactive donor T cells confer rapid and safe systemic reconstitution of virus-specific immunity following stem cell transplantation KS Peggs, K Thomson, E Samuel, G Dyer, J Armoogum, R Chakraverty, ... Clinical infectious diseases 52 (1), 49-57, 2011 | 280 | 2011 |
Polyol synthesis, functionalisation, and biocompatibility studies of superparamagnetic iron oxide nanoparticles as potential MRI contrast agents R Hachani, M Lowdell, M Birchall, A Hervault, D Mertz, S Begin-Colin, ... Nanoscale 8 (6), 3278-3287, 2016 | 235 | 2016 |
The role of Vδ2-negative γδ T cells during cytomegalovirus reactivation in recipients of allogeneic stem cell transplantation A Knight, AJ Madrigal, S Grace, J Sivakumaran, P Kottaridis, S Mackinnon, ... Blood, The Journal of the American Society of Hematology 116 (12), 2164-2172, 2010 | 228 | 2010 |
Immunomodulatory effect of a decellularized skeletal muscle scaffold in a discordant xenotransplantation model JM Fishman, MW Lowdell, L Urbani, T Ansari, AJ Burns, M Turmaine, ... Proceedings of the National Academy of Sciences 110 (35), 14360-14365, 2013 | 223 | 2013 |
Tissue‐engineered tracheal replacement in a child: A 4‐year follow‐up study NJ Hamilton, M Kanani, DJ Roebuck, RJ Hewitt, R Cetto, ... American journal of transplantation 15 (10), 2750-2757, 2015 | 212 | 2015 |
HTT-lowering reverses Huntington’s disease immune dysfunction caused by NFκB pathway dysregulation U Träger, R Andre, N Lahiri, A Magnusson-Lind, A Weiss, S Grueninger, ... Brain 137 (3), 819-833, 2014 | 182 | 2014 |
Loss of CD28 expression on CD8+ T cells is induced by IL-2 receptor γ chain signalling cytokines and type I IFN, and increases susceptibility to activation-induced … NJ Borthwick, M Lowdell, M Salmon, AN Akbar International immunology 12 (7), 1005-1013, 2000 | 180 | 2000 |
Dimethyl sulfoxide: a central player since the dawn of cryobiology, is efficacy balanced by toxicity? M Awan, I Buriak, R Fleck, B Fuller, A Goltsev, J Kerby, M Lowdell, ... Regenerative medicine 15 (3), 1463-1491, 2020 | 176 | 2020 |
Inhibition of human immunodeficiency virus and growth of infected T cells by the immunosuppressive drugs cyclosporin A and FK 506. A Karpas, M Lowdell, SK Jacobson, F Hill Proceedings of the National Academy of Sciences 89 (17), 8351-8355, 1992 | 172 | 1992 |
Evidence that continued remission in patients treated for acute leukaemia is dependent upon autologous natural killer cells MW Lowdell, R Craston, D Samuel, ME Wood, E O'Neill, V Saha, ... British journal of haematology 117 (4), 821-827, 2002 | 160 | 2002 |
Biochemical changes caused by decellularization may compromise mechanical integrity of tracheal scaffolds L Partington, NJ Mordan, C Mason, JC Knowles, HW Kim, MW Lowdell, ... Acta biomaterialia 9 (2), 5251-5261, 2013 | 156 | 2013 |
Temporal dynamics of CD69 expression on lymphoid cells R Craston, M Koh, A Mc Dermott, N Ray, HG Prentice, MW Lowdell Journal of immunological methods 209 (1), 37-45, 1997 | 153 | 1997 |
Analysis of apoptosis in relation to tissue destruction associated with Hashimoto's autoimmune thyroiditis LJ Hammond, MW Lowdell, PG Cerrano, AW Goode, GF Bottazzo, ... The Journal of Pathology: A Journal of the Pathological Society of Great …, 1997 | 145 | 1997 |
Adoptive cellular therapy for cytomegalovirus infection following allogeneic stem cell transplantation using virus-specific T cells S Mackinnon, K Thomson, S Verfuerth, K Peggs, M Lowdell Blood Cells, Molecules, and Diseases 40 (1), 63-67, 2008 | 139 | 2008 |
Ligation of CD8α on human natural killer cells prevents activation‐induced apoptosis and enhances cytolytic activity EG Addison, J North, I Bakhsh, C Marden, S Haq, S Al‐Sarraj, R Malayeri, ... Immunology 116 (3), 354-361, 2005 | 139 | 2005 |
Manufacturing chimeric antigen receptor T cells: issues and challenges C Roddie, M O'Reilly, JDA Pinto, K Vispute, M Lowdell Cytotherapy 21 (3), 327-340, 2019 | 136 | 2019 |
The flow cytometric analysis of telomere length in antigen-specific CD8+ T cells during acute Epstein-Barr virus infection FJ Plunkett, MVD Soares, N Annels, A Hislop, K Ivory, M Lowdell, ... Blood, The Journal of the American Society of Hematology 97 (3), 700-707, 2001 | 127 | 2001 |